ID   QIN_AVIS3               Reviewed;         387 AA.
AC   P56260;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   15-JUL-1998, sequence version 1.
DT   02-JUN-2021, entry version 77.
DE   RecName: Full=Transforming protein Qin;
DE   AltName: Full=Oncogene Qin;
GN   Name=V-QIN;
OS   Avian sarcoma virus (strain 31) (ASV31).
OC   Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes;
OC   Ortervirales; Retroviridae; Orthoretrovirinae; Alpharetrovirus;
OC   unclassified Alpharetrovirus.
OX   NCBI_TaxID=35270;
OH   NCBI_TaxID=8976; Galliformes.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=8099441; DOI=10.1073/pnas.90.10.4490;
RA   Li J., Vogt P.K.;
RT   "The retroviral oncogene qin belongs to the transcription factor family
RT   that includes the homeotic gene fork head.";
RL   Proc. Natl. Acad. Sci. U.S.A. 90:4490-4494(1993).
CC   -!- SUBCELLULAR LOCATION: Host nucleus.
CC   -!- MISCELLANEOUS: This protein is synthesized as a Gag-Qin polyprotein.
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DR   EMBL; L10719; -; NOT_ANNOTATED_CDS; mRNA.
DR   BMRB; P56260; -.
DR   SMR; P56260; -.
DR   PRIDE; P56260; -.
DR   GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   CDD; cd00059; FH; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR001766; Fork_head_dom.
DR   InterPro; IPR018122; TF_fork_head_CS_1.
DR   InterPro; IPR030456; TF_fork_head_CS_2.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00250; Forkhead; 1.
DR   PRINTS; PR00053; FORKHEAD.
DR   SMART; SM00339; FH; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS00657; FORK_HEAD_1; 1.
DR   PROSITE; PS00658; FORK_HEAD_2; 1.
DR   PROSITE; PS50039; FORK_HEAD_3; 1.
PE   2: Evidence at transcript level;
KW   DNA-binding; Host nucleus; Oncogene.
FT   CHAIN           1..387
FT                   /note="Transforming protein Qin"
FT                   /id="PRO_0000091840"
FT   DNA_BIND        142..233
FT                   /note="Fork-head"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00089"
FT   REGION          28..80
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          101..143
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        38..57
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        104..142
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   387 AA;  42283 MW;  FEA902F50FFE42F9 CRC64;
     MLDMGDRKEV KMLPKSSFSI NNLVPEAVQS DNHSGHSHHN SHHPHHHHHH HHHHPPPPQQ
     PQRAAAAEEE DEEKAPLLLP PPAAGALEAA KAEALAGKGE AGAAAAELEE KEKAAEEKKG
     AAEGGKDGES GKEGEKKNGK YEKPPFSYNA LIMMAIRQSP EKRLTLNGIY EFIMKNFPYY
     RENKQGWQNS IRHNLSLNKC FVKVPRHYDD PGKGNYWMLD PSSDDVFIGG TTDKLRRRST
     TSRAKLAFKR GARLTSTGLT FMDRAGSLYW PMSPFLSLHH PRASSTLSYN GTASAYPSHP
     MPYSSVLTQN SLGNNHSFST SNGLSVDRLV NGEIPYATHH LTAAALAASV PCGLSVPCSG
     TYSLNPCSVN LLAGQTSYFS PTSLTPQ