QKIL3_ARATH
ID QKIL3_ARATH Reviewed; 286 AA.
AC Q9ZVI3;
DT 16-DEC-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 25-MAY-2022, entry version 124.
DE RecName: Full=KH domain-containing protein At2g38610;
DE AltName: Full=Quaking-like protein 3;
GN OrderedLocusNames=At2g38610; ORFNames=T6A23.19;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP GENE FAMILY.
RX PubMed=11809873; DOI=10.1093/nar/30.3.623;
RA Lorkovic Z.J., Barta A.;
RT "Genome analysis: RNA recognition motif (RRM) and K homology (KH) domain
RT RNA-binding proteins from the flowering plant Arabidopsis thaliana.";
RL Nucleic Acids Res. 30:623-635(2002).
RN [5]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-263 AND SER-273, AND
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=19376835; DOI=10.1104/pp.109.138677;
RA Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,
RA Grossmann J., Gruissem W., Baginsky S.;
RT "Large-scale Arabidopsis phosphoproteome profiling reveals novel
RT chloroplast kinase substrates and phosphorylation networks.";
RL Plant Physiol. 150:889-903(2009).
RN [6]
RP ACETYLATION [LARGE SCALE ANALYSIS] AT SER-2, CLEAVAGE OF INITIATOR
RP METHIONINE [LARGE SCALE ANALYSIS], AND IDENTIFICATION BY MASS SPECTROMETRY
RP [LARGE SCALE ANALYSIS].
RX PubMed=22223895; DOI=10.1074/mcp.m111.015131;
RA Bienvenut W.V., Sumpton D., Martinez A., Lilla S., Espagne C., Meinnel T.,
RA Giglione C.;
RT "Comparative large-scale characterisation of plant vs. mammal proteins
RT reveals similar and idiosyncratic N-alpha acetylation features.";
RL Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012).
CC -!- INTERACTION:
CC Q9ZVI3; Q9SHZ6: UBA1A; NbExp=3; IntAct=EBI-4440478, EBI-346271;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
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DR EMBL; AC005499; AAC67357.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC09555.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC09556.1; -; Genomic_DNA.
DR EMBL; AY042804; AAK68744.1; -; mRNA.
DR EMBL; AY064682; AAL47387.1; -; mRNA.
DR EMBL; AY065112; AAL38288.1; -; mRNA.
DR EMBL; BT000084; AAN15403.1; -; mRNA.
DR PIR; B84807; B84807.
DR RefSeq; NP_181395.1; NM_129418.3.
DR RefSeq; NP_850296.1; NM_179965.4.
DR AlphaFoldDB; Q9ZVI3; -.
DR SMR; Q9ZVI3; -.
DR BioGRID; 3785; 4.
DR IntAct; Q9ZVI3; 4.
DR STRING; 3702.AT2G38610.1; -.
DR iPTMnet; Q9ZVI3; -.
DR PaxDb; Q9ZVI3; -.
DR PRIDE; Q9ZVI3; -.
DR ProteomicsDB; 225935; -.
DR EnsemblPlants; AT2G38610.1; AT2G38610.1; AT2G38610.
DR EnsemblPlants; AT2G38610.2; AT2G38610.2; AT2G38610.
DR GeneID; 818443; -.
DR Gramene; AT2G38610.1; AT2G38610.1; AT2G38610.
DR Gramene; AT2G38610.2; AT2G38610.2; AT2G38610.
DR KEGG; ath:AT2G38610; -.
DR Araport; AT2G38610; -.
DR TAIR; locus:2064097; AT2G38610.
DR eggNOG; KOG1588; Eukaryota.
DR HOGENOM; CLU_065679_0_1_1; -.
DR InParanoid; Q9ZVI3; -.
DR OMA; AEHQKFG; -.
DR OrthoDB; 1565749at2759; -.
DR PhylomeDB; Q9ZVI3; -.
DR PRO; PR:Q9ZVI3; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9ZVI3; baseline and differential.
DR Genevisible; Q9ZVI3; AT.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003729; F:mRNA binding; IDA:TAIR.
DR GO; GO:0048024; P:regulation of mRNA splicing, via spliceosome; IBA:GO_Central.
DR Gene3D; 3.30.1370.10; -; 1.
DR InterPro; IPR045071; BBP-like.
DR InterPro; IPR004087; KH_dom.
DR InterPro; IPR004088; KH_dom_type_1.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR InterPro; IPR032377; STAR_dimer.
DR PANTHER; PTHR11208; PTHR11208; 1.
DR Pfam; PF00013; KH_1; 1.
DR Pfam; PF16544; STAR_dimer; 1.
DR SMART; SM00322; KH; 1.
DR SUPFAM; SSF54791; SSF54791; 1.
PE 1: Evidence at protein level;
KW Acetylation; Nucleus; Phosphoprotein; Reference proteome; RNA-binding.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0007744|PubMed:22223895"
FT CHAIN 2..286
FT /note="KH domain-containing protein At2g38610"
FT /id="PRO_0000357030"
FT DOMAIN 141..208
FT /note="KH"
FT REGION 256..286
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 2
FT /note="N-acetylserine"
FT /evidence="ECO:0007744|PubMed:22223895"
FT MOD_RES 263
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:19376835"
FT MOD_RES 273
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:19376835"
SQ SEQUENCE 286 AA; 31721 MW; 12ABFC0228E6877E CRC64;
MSGLYNNSSY FSPARAASPQ IRSTPEIDSS QYLTELLAEH QKLTPFMQVL PICSRLLNQE
MFRVSGMMSN QGFGDFDRLR HRSPSPMASS NLMSNVSNTG LGGWNGLSQE RLSGTPGMTM
DWQGAPGSPS SYTVKRILRL EIPVDNYPNF NFVGRLLGPR GNSLKRVEAT TGCRVFIRGK
GSIKDPEKED KLRGRPGYEH LNEQLHILIE ADLPASIVEI RLRQAQEIIE ELLKPVDESQ
DFIKRQQLRE LALLNSNNLR EESPGPSGGG SVSPFNSSGK RPKTGC
