ID   QORL2_RAT               Reviewed;         350 AA.
AC   B0BNC9;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   26-FEB-2008, sequence version 1.
DT   03-AUG-2022, entry version 76.
DE   RecName: Full=Quinone oxidoreductase-like protein 2;
DE            EC=1.-.-.-;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Lung;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC       family. Quinone oxidoreductase subfamily. {ECO:0000305}.
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DR   EMBL; BC158771; AAI58772.1; -; mRNA.
DR   RefSeq; XP_006250102.1; XM_006250040.3.
DR   AlphaFoldDB; B0BNC9; -.
DR   SMR; B0BNC9; -.
DR   STRING; 10116.ENSRNOP00000006924; -.
DR   PhosphoSitePlus; B0BNC9; -.
DR   PaxDb; B0BNC9; -.
DR   PeptideAtlas; B0BNC9; -.
DR   PRIDE; B0BNC9; -.
DR   Ensembl; ENSRNOT00000006924; ENSRNOP00000006924; ENSRNOG00000005177.
DR   GeneID; 289138; -.
DR   UCSC; RGD:1304982; rat.
DR   CTD; 226527; -.
DR   RGD; 1304982; RGD1304982.
DR   eggNOG; KOG1198; Eukaryota.
DR   GeneTree; ENSGT00940000162916; -.
DR   HOGENOM; CLU_026673_3_1_1; -.
DR   InParanoid; B0BNC9; -.
DR   OMA; FWGEFAR; -.
DR   OrthoDB; 929126at2759; -.
DR   PhylomeDB; B0BNC9; -.
DR   TreeFam; TF314255; -.
DR   PRO; PR:B0BNC9; -.
DR   Proteomes; UP000002494; Chromosome 13.
DR   Bgee; ENSRNOG00000005177; Expressed in adult mammalian kidney and 18 other tissues.
DR   ExpressionAtlas; B0BNC9; baseline and differential.
DR   Genevisible; B0BNC9; RN.
DR   GO; GO:0070402; F:NADPH binding; ISO:RGD.
DR   GO; GO:0003960; F:NADPH:quinone reductase activity; ISO:RGD.
DR   GO; GO:0016491; F:oxidoreductase activity; IBA:GO_Central.
DR   GO; GO:0042803; F:protein homodimerization activity; ISO:RGD.
DR   GO; GO:0048038; F:quinone binding; ISO:RGD.
DR   GO; GO:0006739; P:NADP metabolic process; ISO:RGD.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR013154; ADH_N.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; SSF50129; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
PE   2: Evidence at transcript level;
KW   Acetylation; Oxidoreductase; Reference proteome.
FT   CHAIN           1..350
FT                   /note="Quinone oxidoreductase-like protein 2"
FT                   /id="PRO_0000341240"
FT   MOD_RES         36
FT                   /note="N6-acetyllysine"
FT                   /evidence="ECO:0000250|UniProtKB:Q3UNZ8"
FT   MOD_RES         201
FT                   /note="N6-succinyllysine"
FT                   /evidence="ECO:0000250|UniProtKB:Q3UNZ8"
FT   MOD_RES         302
FT                   /note="N6-acetyllysine"
FT                   /evidence="ECO:0000250|UniProtKB:Q3UNZ8"
FT   MOD_RES         328
FT                   /note="N6-acetyllysine"
FT                   /evidence="ECO:0000250|UniProtKB:Q3UNZ8"
SQ   SEQUENCE   350 AA;  37548 MW;  4EE9C8C05A90D4A2 CRC64;
     MAARLCARCL PPAWLCRQAG QGQSRHYRAA VCTELKQPLT IQEVAPRPIG PQEVRVDVHF
     CGINFADNLV CRGQYQEKPP LPFTPGMEFS GVVLEAGADV STVKKGDRVI GVSNFHSMAE
     QCITDQKTLW RIPENVSLQD AAVLPVSYGT AILAVDHRAR IQPGETVLVT AAAGATGLAV
     IDVATNVFCA KVIAAAGSDE KCKLAMQRGA QSGVNYSQGS LKDAVKKLVG SSGVNVAIDM
     VGGDVFLDSL RSLAWEGRIV VLGFAGGNIA SVPSNLLLLK NISAMGLYWG RYQHQDFAVF
     SKSMSTALQY CQQGLIHPHT GAVFKLEKVN DAFLHVMQRK STGKVLLSLK