ID   QOX2_ACEAC              Reviewed;         307 AA.
AC   P50653;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   25-MAY-2022, entry version 102.
DE   RecName: Full=Ubiquinol oxidase subunit 2;
DE            EC=1.10.3.-;
DE   AltName: Full=Cytochrome A1 subunit 2;
DE   AltName: Full=Oxidase BA(3) subunit 2;
DE   AltName: Full=Ubiquinol oxidase polypeptide II;
DE   Flags: Precursor;
GN   Name=cyaB;
OS   Acetobacter aceti.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodospirillales;
OC   Acetobacteraceae; Acetobacter; Acetobacter subgen. Acetobacter.
OX   NCBI_TaxID=435;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=1023;
RX   PubMed=8392509; DOI=10.1128/jb.175.14.4307-4314.1993;
RA   Fukaya M., Tayama K., Tamaki T., Ebisuya H., Okumura H., Kawamura Y.,
RA   Horinouchi S., Beppu T.;
RT   "Characterization of a cytochrome a1 that functions as a ubiquinol oxidase
RT   in Acetobacter aceti.";
RL   J. Bacteriol. 175:4307-4314(1993).
CC   -!- SUBUNIT: Heterotetramer of the subunits 1, 2, 3 and 4.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the cytochrome c oxidase subunit 2 family.
CC       {ECO:0000305}.
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DR   EMBL; D13185; BAA02480.1; -; Genomic_DNA.
DR   PIR; A36885; A36885.
DR   AlphaFoldDB; P50653; -.
DR   SMR; P50653; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0070469; C:respirasome; IEA:UniProtKB-KW.
DR   GO; GO:0005507; F:copper ion binding; IEA:InterPro.
DR   GO; GO:0009486; F:cytochrome bo3 ubiquinol oxidase activity; IEA:InterPro.
DR   GO; GO:0004129; F:cytochrome-c oxidase activity; IEA:InterPro.
DR   GO; GO:0016682; F:oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor; IEA:InterPro.
DR   CDD; cd04212; CuRO_UO_II; 1.
DR   Gene3D; 1.10.287.90; -; 1.
DR   Gene3D; 2.60.40.420; -; 1.
DR   InterPro; IPR045187; CcO_II.
DR   InterPro; IPR002429; CcO_II-like_C.
DR   InterPro; IPR010514; COX_ARM.
DR   InterPro; IPR008972; Cupredoxin.
DR   InterPro; IPR034227; CuRO_UO_II.
DR   InterPro; IPR011759; Cyt_c_oxidase_su2_TM_dom.
DR   InterPro; IPR036257; Cyt_c_oxidase_su2_TM_sf.
DR   InterPro; IPR006333; Cyt_o_ubiquinol_oxidase_su2.
DR   PANTHER; PTHR22888; PTHR22888; 1.
DR   Pfam; PF00116; COX2; 1.
DR   Pfam; PF06481; COX_ARM; 1.
DR   PIRSF; PIRSF000292; Ubi_od_II; 1.
DR   SUPFAM; SSF49503; SSF49503; 1.
DR   SUPFAM; SSF81464; SSF81464; 1.
DR   TIGRFAMs; TIGR01433; CyoA; 1.
DR   PROSITE; PS50857; COX2_CUA; 1.
DR   PROSITE; PS50999; COX2_TM; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Electron transport; Lipoprotein; Membrane; Oxidoreductase;
KW   Palmitate; Respiratory chain; Signal; Transmembrane; Transmembrane helix;
KW   Transport.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           24..307
FT                   /note="Ubiquinol oxidase subunit 2"
FT                   /id="PRO_0000006070"
FT   TRANSMEM        46..66
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        87..107
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   LIPID           24
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           24
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ   SEQUENCE   307 AA;  33921 MW;  E66734B84410996D CRC64;
     MKNKLLARVA RLGGLSSALL LAGCELDVLD PKGPVGEGVK TLIATSTVAM LIVVIPTILE
     TLLFAWQYRQ SNTSAEYLPK WCHSNKIEVT IWGVPSLIIL FLAVITYQTC HSLDPYKPLE
     AEANTKPLHV EVVALDWKWL FIYPEQGIAT VNQLAIPVNT PIDFNITSDS VMNSFFIPRL
     GSMIYAMAGM QTQLHLLASE PGDYLGESAN YSGRGFSDMK FHTLAVSGDE FNAWVEKVKS
     SSEQLDSQTY PKLAAPSENP VEYFAHVEPG MFNTIVAKYN NGMVMDKSTG KMIQVQQSAM
     SDMNMKE