QPTR_BACSU
ID QPTR_BACSU Reviewed; 229 AA.
AC P54163;
DT 01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1996, sequence version 1.
DT 03-AUG-2022, entry version 120.
DE RecName: Full=Probable queuosine precursor transporter {ECO:0000255|HAMAP-Rule:MF_02088};
DE Short=Q precursor transporter {ECO:0000255|HAMAP-Rule:MF_02088};
GN Name=ypdP; OrderedLocusNames=BSU21980;
OS Bacillus subtilis (strain 168).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=224308;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=168 / Marburg / ATCC 6051 / DSM 10 / JCM 1465 / NBRC 13719 / NCIMB
RC 3610 / NRRL NRS-744 / VKM B-501;
RX PubMed=8969496; DOI=10.1099/13500872-142-11-3005;
RA Capuano V., Galleron N., Pujic P., Sorokin A., Ehrlich S.D.;
RT "Organization of the Bacillus subtilis 168 chromosome between kdg and the
RT attachment site of the SP beta prophage: use of long accurate PCR and yeast
RT artificial chromosomes for sequencing.";
RL Microbiology 142:3005-3015(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=168;
RX PubMed=9384377; DOI=10.1038/36786;
RA Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA Yoshikawa H., Danchin A.;
RT "The complete genome sequence of the Gram-positive bacterium Bacillus
RT subtilis.";
RL Nature 390:249-256(1997).
CC -!- FUNCTION: Involved in the import of queuosine (Q) precursors, required
CC for Q precursor salvage. {ECO:0000255|HAMAP-Rule:MF_02088}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_02088,
CC ECO:0000305}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_02088}.
CC -!- SIMILARITY: Belongs to the vitamin uptake transporter (VUT/ECF) (TC
CC 2.A.88) family. Q precursor transporter subfamily. {ECO:0000255|HAMAP-
CC Rule:MF_02088, ECO:0000305}.
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DR EMBL; L77246; AAA96619.1; -; Genomic_DNA.
DR EMBL; AL009126; CAB14116.1; -; Genomic_DNA.
DR PIR; C69934; C69934.
DR RefSeq; NP_390081.1; NC_000964.3.
DR RefSeq; WP_003230767.1; NZ_JNCM01000036.1.
DR AlphaFoldDB; P54163; -.
DR STRING; 224308.BSU21980; -.
DR TCDB; 2.A.88.8.2; the vitamin uptake transporter (vut) family.
DR PaxDb; P54163; -.
DR EnsemblBacteria; CAB14116; CAB14116; BSU_21980.
DR GeneID; 939075; -.
DR KEGG; bsu:BSU21980; -.
DR PATRIC; fig|224308.179.peg.2400; -.
DR eggNOG; COG1738; Bacteria.
DR InParanoid; P54163; -.
DR OMA; IFQKFFY; -.
DR PhylomeDB; P54163; -.
DR BioCyc; BSUB:BSU21980-MON; -.
DR Proteomes; UP000001570; Chromosome.
DR GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:1990397; P:queuosine salvage; IEA:UniProtKB-UniRule.
DR HAMAP; MF_02088; Q_prec_transport; 1.
DR InterPro; IPR003744; YhhQ.
DR PANTHER; PTHR34300; PTHR34300; 1.
DR Pfam; PF02592; Vut_1; 1.
DR TIGRFAMs; TIGR00697; TIGR00697; 1.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..229
FT /note="Probable queuosine precursor transporter"
FT /id="PRO_0000049687"
FT TRANSMEM 6..26
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_02088"
FT TRANSMEM 28..48
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_02088"
FT TRANSMEM 49..69
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_02088"
FT TRANSMEM 86..106
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_02088"
FT TRANSMEM 118..138
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_02088"
FT TRANSMEM 160..182
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_02088"
FT TRANSMEM 192..214
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_02088"
SQ SEQUENCE 229 AA; 25671 MW; 14CFE0A9377005CB CRC64;
MFNNSFWIFF AIIHFIIVLL FYKGFGKMGL FVWIGFATVC ANLQVVKTVE LFGLTATLGN
VMYGTIFFAT DVLNEKYGPA EARKAVWLGF STLLTLTFVM QGVLLFEPAS SDISQTALET
IFGFLPRVAL GSLLAFIFSQ TLDVYVYSAI RRIFPSDRLL WLRNGGSTAV SQLFDTFIFT
AVAFLGIYPA DVWLHIFIST YLIKFAVSLI SLPYAYAAKK MIPNDERSS
