ID   QSEB_SALTY              Reviewed;         219 AA.
AC   P66795; Q8XEQ3;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 100.
DE   RecName: Full=Transcriptional regulatory protein QseB;
GN   Name=qseB; OrderedLocusNames=STM3177;
OS   Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=99287;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX   PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA   Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL   Nature 413:852-856(2001).
CC   -!- FUNCTION: Member of a two-component regulatory system QseB/QseC.
CC       Activates the flagella regulon by activating transcription of flhDC (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- PTM: Phosphorylated by QseC. {ECO:0000305}.
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DR   EMBL; AE006468; AAL22051.1; -; Genomic_DNA.
DR   RefSeq; NP_462092.1; NC_003197.2.
DR   RefSeq; WP_001221574.1; NC_003197.2.
DR   AlphaFoldDB; P66795; -.
DR   SMR; P66795; -.
DR   STRING; 99287.STM3177; -.
DR   PaxDb; P66795; -.
DR   EnsemblBacteria; AAL22051; AAL22051; STM3177.
DR   GeneID; 1254700; -.
DR   KEGG; stm:STM3177; -.
DR   PATRIC; fig|99287.12.peg.3368; -.
DR   HOGENOM; CLU_000445_30_1_6; -.
DR   OMA; SYPRRVW; -.
DR   PhylomeDB; P66795; -.
DR   BioCyc; SENT99287:STM3177-MON; -.
DR   Proteomes; UP000001014; Chromosome.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0032993; C:protein-DNA complex; IBA:GO_Central.
DR   GO; GO:0001216; F:DNA-binding transcription activator activity; IBA:GO_Central.
DR   GO; GO:0000156; F:phosphorelay response regulator activity; IBA:GO_Central.
DR   GO; GO:0000976; F:transcription cis-regulatory region binding; IBA:GO_Central.
DR   CDD; cd00383; trans_reg_C; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR011006; CheY-like_superfamily.
DR   InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR   InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR   InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR   InterPro; IPR039420; WalR-like.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR48111; PTHR48111; 1.
DR   Pfam; PF00072; Response_reg; 1.
DR   Pfam; PF00486; Trans_reg_C; 1.
DR   SMART; SM00448; REC; 1.
DR   SMART; SM00862; Trans_reg_C; 1.
DR   SUPFAM; SSF46894; SSF46894; 1.
DR   SUPFAM; SSF52172; SSF52172; 1.
DR   PROSITE; PS51755; OMPR_PHOB; 1.
DR   PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE   3: Inferred from homology;
KW   Activator; Cytoplasm; DNA-binding; Phosphoprotein; Reference proteome;
KW   Transcription; Transcription regulation; Two-component regulatory system.
FT   CHAIN           1..219
FT                   /note="Transcriptional regulatory protein QseB"
FT                   /id="PRO_0000081028"
FT   DOMAIN          2..116
FT                   /note="Response regulatory"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT   DNA_BIND        124..218
FT                   /note="OmpR/PhoB-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01091"
FT   MOD_RES         51
FT                   /note="4-aspartylphosphate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
SQ   SEQUENCE   219 AA;  24274 MW;  F23F90CA123EB2FA CRC64;
     MRILLVEDDT LIGDGIKAGL SKMGFSVDWF TEGRPGKEAL YSAPYDAVIL DLTLPGMDGR
     DILREWREKG KQEPVLILTA RDALAERVEG LRLGADDYLC KPFALIEVAA RLEALVRRAS
     GQASSELRHG QVTLNPGNLV ATLAGEPLAL KPKEFALLEL LLRNKGRVLP RKLIEEKLYN
     WDDDVSSNAV EVHVHHLRRK LGSEFIRTVH GIGYTLGDA