QSPP_SCHPO
ID QSPP_SCHPO Reviewed; 346 AA.
AC Q9HDZ9;
DT 08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 25-MAY-2022, entry version 84.
DE RecName: Full=Queuosine salvage protein {ECO:0000303|PubMed:24911101};
GN ORFNames=SPAC589.05c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP FUNCTION, AND DISRUPTION PHENOTYPE.
RX PubMed=24911101; DOI=10.1021/cb500278k;
RA Zallot R., Brochier-Armanet C., Gaston K.W., Forouhar F., Limbach P.A.,
RA Hunt J.F., de Crecy-Lagard V.;
RT "Plant, animal, and fungal micronutrient queuosine is salvaged by members
RT of the DUF2419 protein family.";
RL ACS Chem. Biol. 9:1812-1825(2014).
CC -!- FUNCTION: Involved in salvaging queuosine.
CC {ECO:0000269|PubMed:24911101}.
CC -!- DISRUPTION PHENOTYPE: Lacks queuosine in tRNA(Asp).
CC {ECO:0000269|PubMed:24911101}.
CC -!- SIMILARITY: Belongs to the queuosine salvage protein family.
CC {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CU329670; CAC19762.1; -; Genomic_DNA.
DR RefSeq; NP_594053.1; NM_001019477.2.
DR AlphaFoldDB; Q9HDZ9; -.
DR BioGRID; 279035; 1.
DR STRING; 4896.SPAC589.05c.1; -.
DR MaxQB; Q9HDZ9; -.
DR PaxDb; Q9HDZ9; -.
DR PRIDE; Q9HDZ9; -.
DR EnsemblFungi; SPAC589.05c.1; SPAC589.05c.1:pep; SPAC589.05c.
DR GeneID; 2542579; -.
DR KEGG; spo:SPAC589.05c; -.
DR PomBase; SPAC589.05c; -.
DR VEuPathDB; FungiDB:SPAC589.05c; -.
DR eggNOG; KOG2524; Eukaryota.
DR HOGENOM; CLU_036001_2_1_1; -.
DR InParanoid; Q9HDZ9; -.
DR OMA; LEHIPFH; -.
DR PhylomeDB; Q9HDZ9; -.
DR PRO; PR:Q9HDZ9; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0005829; C:cytosol; HDA:PomBase.
DR GO; GO:0008477; F:purine nucleosidase activity; TAS:PomBase.
DR GO; GO:0006400; P:tRNA modification; IBA:GO_Central.
DR GO; GO:0101030; P:tRNA-guanine transglycosylation; IMP:PomBase.
DR InterPro; IPR019438; Q_salvage.
DR PANTHER; PTHR21314; PTHR21314; 1.
DR Pfam; PF10343; Q_salvage; 1.
PE 3: Inferred from homology;
KW Reference proteome.
FT CHAIN 1..346
FT /note="Queuosine salvage protein"
FT /id="PRO_0000327925"
SQ SEQUENCE 346 AA; 39792 MW; 23501C1CE7E43119 CRC64;
MSRVLQDAEF ISLNSNDVKV NKGGCAAVAT WIKEKLDSLG PQFAEWQNHE LHPKTRDVST
LDWIFLVDIL NFSFWSDVDV EDSGKHSKRF SIEYKGKLYT GYWSLCAAIN KALDAGIPIT
SPAFYADEKQ CPDTLIASVF DSATVEKIPL LEERIRIMRA SGRVLVDSYH GSYCGLLKKC
HNQAQRLIKL LLADFPDFRD VSVYKGRECY MLKRAQILVA ETWACFQGQN YGRFDDIDSI
TMFADYRVPQ ILWQLGCLSY SSDFKKRLLK NELIAHNDPM EIEMRGCSIW AVEKILQNIN
RKDVNAITID FFLWDLAKEW QAKGYKPSTQ VDEVTIPCIR VRSIYY