ID   AAEB_EDWI9              Reviewed;         648 AA.
AC   C5BC09;
DT   16-NOV-2011, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=p-hydroxybenzoic acid efflux pump subunit AaeB {ECO:0000255|HAMAP-Rule:MF_01545};
DE            Short=pHBA efflux pump protein B {ECO:0000255|HAMAP-Rule:MF_01545};
GN   Name=aaeB {ECO:0000255|HAMAP-Rule:MF_01545}; OrderedLocusNames=NT01EI_3480;
OS   Edwardsiella ictaluri (strain 93-146).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Hafniaceae; Edwardsiella.
OX   NCBI_TaxID=634503;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=93-146;
RA   Williams M.L., Gillaspy A.F., Dyer D.W., Thune R.L., Waldbieser G.C.,
RA   Schuster S.C., Gipson J., Zaitshik J., Landry C., Lawrence M.L.;
RT   "Complete genome sequence of Edwardsiella ictaluri 93-146.";
RL   Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Forms an efflux pump with AaeA. Could function as a metabolic
CC       relief valve, allowing to eliminate certain compounds when they
CC       accumulate to high levels in the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01545}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01545}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01545}.
CC   -!- SIMILARITY: Belongs to the aromatic acid exporter ArAE (TC 2.A.85)
CC       family. {ECO:0000255|HAMAP-Rule:MF_01545}.
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DR   EMBL; CP001600; ACR70616.1; -; Genomic_DNA.
DR   RefSeq; WP_015872688.1; NC_012779.2.
DR   AlphaFoldDB; C5BC09; -.
DR   EnsemblBacteria; ACR70616; ACR70616; NT01EI_3480.
DR   GeneID; 7962478; -.
DR   KEGG; eic:NT01EI_3480; -.
DR   PATRIC; fig|634503.3.peg.3098; -.
DR   HOGENOM; CLU_027647_0_0_6; -.
DR   OMA; MITQACE; -.
DR   OrthoDB; 1320135at2; -.
DR   Proteomes; UP000001485; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0046942; P:carboxylic acid transport; IEA:InterPro.
DR   HAMAP; MF_01545; AaeB; 1.
DR   InterPro; IPR006726; PHBA_efflux_AaeB/fusaric-R.
DR   InterPro; IPR023706; PHBA_efflux_pump_AaeB.
DR   PANTHER; PTHR30509:SF10; PTHR30509:SF10; 1.
DR   Pfam; PF04632; FUSC; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..648
FT                   /note="p-hydroxybenzoic acid efflux pump subunit AaeB"
FT                   /id="PRO_0000414000"
FT   TRANSMEM        11..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        41..61
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        65..87
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        91..110
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        125..145
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        150..170
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        369..389
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        406..426
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        430..450
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        458..478
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        481..501
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
SQ   SEQUENCE   648 AA;  70170 MW;  EFBBA8FBD4B0543F CRC64;
     MLYPRAIRLR FACKLTLASV LSLLLGFYFG LPMPRWSALT AALVAAAPAF AAGGEPFSGA
     IRYRGWLRII GTVLGSLCAL LLMMLLIRAP LLMILLCCLW AGVCTWLSSL VRMENSYALG
     LSGYTALIIV VSCLGEPQFI LQLALERCGE IVLGIVCAVL VDTLLAPRSV KGEVDRVVGG
     MLLGQLRLLQ CCVDGRDGDA IDRSWHRLIR ESHTLEEMRA SLALESSRWP RACRRLTALH
     TLSLTLITRA CEIFLTQCQT PMALPAPFLA LIAAPVDTPE EAYQRLKQLR RLLVAHGEHQ
     LPPALIGWIG GASRLQLLVK GVASNVRIGR YEAATLAHDT APRPLYSVQG HHALINGLRT
     WLATSLGALF WLWSGWSAGS GCMIMIAVVT SLAVRTPNPR MAAIDFLMGS LVALPVGALY
     YTLILPATQQ SLVLLCLSLG ALTFICGMAV QKRRLGSMGT LASTLNILAL SNPMGFPIER
     FVDSAIGQMV GCLLALVVLL VVHDRSRART GRALMRHLAF GAVAALRREG TRGNLLPALY
     RQLLLLLTLF PDDIGRYRLA LTLIVLQQRL AHSALPCDAG RLRAIDAAAT RLLSGGGSAR
     CSGALLQLTT ELGDYADCLA RQGIASAVLQ PLHQLADVLY RYRSVLLD