ID   AAEB_EDWTF              Reviewed;         648 AA.
AC   E0T8U0;
DT   16-NOV-2011, integrated into UniProtKB/Swiss-Prot.
DT   02-NOV-2010, sequence version 1.
DT   03-AUG-2022, entry version 55.
DE   RecName: Full=p-hydroxybenzoic acid efflux pump subunit AaeB;
DE            Short=pHBA efflux pump protein B;
GN   Name=aaeB; OrderedLocusNames=ETAF_2821;
OS   Edwardsiella tarda (strain FL6-60).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Hafniaceae; Edwardsiella.
OX   NCBI_TaxID=718251;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FL6-60;
RA   van Soest J.J., Henkel C.V., Jansen H.J., van den Hondel C.A.M.J.J.,
RA   Bloemberg G.V., Meijer A.H., Spaink H.P.;
RT   "Genome comparisons of Edwardsiella bacteria analysed using deep sequencing
RT   technology.";
RL   Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Forms an efflux pump with AaeA. Could function as a metabolic
CC       relief valve, allowing to eliminate certain compounds when they
CC       accumulate to high levels in the cell (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the aromatic acid exporter ArAE (TC 2.A.85)
CC       family. {ECO:0000305}.
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DR   EMBL; CP002154; ADM42923.1; -; Genomic_DNA.
DR   RefSeq; WP_012849938.1; NC_017309.1.
DR   AlphaFoldDB; E0T8U0; -.
DR   EnsemblBacteria; ADM42923; ADM42923; ETAF_2821.
DR   KEGG; etd:ETAF_2821; -.
DR   PATRIC; fig|718251.5.peg.2940; -.
DR   HOGENOM; CLU_027647_0_0_6; -.
DR   OMA; MITQACE; -.
DR   Proteomes; UP000002230; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0046942; P:carboxylic acid transport; IEA:InterPro.
DR   InterPro; IPR006726; PHBA_efflux_AaeB/fusaric-R.
DR   InterPro; IPR023706; PHBA_efflux_pump_AaeB.
DR   PANTHER; PTHR30509:SF10; PTHR30509:SF10; 1.
DR   Pfam; PF04632; FUSC; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..648
FT                   /note="p-hydroxybenzoic acid efflux pump subunit AaeB"
FT                   /id="PRO_0000414001"
FT   TRANSMEM        11..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        41..61
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        65..87
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        91..110
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        125..145
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        150..170
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        369..389
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        406..426
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        430..450
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        455..474
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        481..501
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   648 AA;  69879 MW;  0DDE4A171A202F47 CRC64;
     MLHPRVIRLR FACKLTLAIV LSLLLGFYFG LQTPRWSALT AALVAAGPAF AAGGEPFAGA
     IRYRGWLRII GTVLGSLCAL LLMMLLIRAP LLMILLCCLW AGVCTWLSSL VRMENAYALG
     LSGYTALIIV VSCLGEPQFI LQLALERCGE IVLGIACAVL ADTLLAPRSV KGEVDRVVGG
     MLLGQLCLLQ RCVDGRDSDA VDRSWHGLIR ESHTLEGMRA SLALESSRWP RACRRLAALH
     TLSLTLITRA CEIFLTQRQT PTALPAPFLT LIAAPVKTPA EAYQRLKQLR RLLAAHGGHQ
     LPPALIGWID GASQLQLLAK GVASNVRIGR HEAAILAHDA APRQIYSAQG HHALINGLRT
     WLATSLGALF WLWSGWNAGS GCMIMIAVVT SLAVRTPNPR MAAIDFLMGS LVALPVGALY
     YTVILPATQQ SLVLLCLSLG ALTFICGMEV QKRRLGSLGT LASTLNILVL SNPMRFPIES
     FVDSAIGQVI GCLLALVVLL AVRDRSRART GRTLMRRLAF GAVAALRGEG TRGNLLPALY
     RQLFLLLTLF PDDIGRYRLA LTLIVLQQRL AHSALPCDAE RLRAIDAAAT RLLTGRGAAR
     RRGALLQLTT GLSDYADALV RQGAAGAALQ PLHQLADVLH RYRGVLLG