ID   AAEB_ERWBE              Reviewed;         652 AA.
AC   D8MXN7;
DT   16-NOV-2011, integrated into UniProtKB/Swiss-Prot.
DT   05-OCT-2010, sequence version 1.
DT   03-AUG-2022, entry version 61.
DE   RecName: Full=p-hydroxybenzoic acid efflux pump subunit AaeB {ECO:0000255|HAMAP-Rule:MF_01545};
DE            Short=pHBA efflux pump protein B {ECO:0000255|HAMAP-Rule:MF_01545};
GN   Name=aaeB {ECO:0000255|HAMAP-Rule:MF_01545}; OrderedLocusNames=EbC_40630;
OS   Erwinia billingiae (strain Eb661).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Erwiniaceae; Erwinia.
OX   NCBI_TaxID=634500;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Eb661;
RX   PubMed=20565991; DOI=10.1186/1471-2164-11-393;
RA   Kube M., Migdoll A.M., Gehring I., Heitmann K., Mayer Y., Kuhl H.,
RA   Knaust F., Geider K., Reinhardt R.;
RT   "Genome comparison of the epiphytic bacteria Erwinia billingiae and E.
RT   tasmaniensis with the pear pathogen E. pyrifoliae.";
RL   BMC Genomics 11:393-393(2010).
CC   -!- FUNCTION: Forms an efflux pump with AaeA. Could function as a metabolic
CC       relief valve, allowing to eliminate certain compounds when they
CC       accumulate to high levels in the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01545}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01545}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01545}.
CC   -!- SIMILARITY: Belongs to the aromatic acid exporter ArAE (TC 2.A.85)
CC       family. {ECO:0000255|HAMAP-Rule:MF_01545}.
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DR   EMBL; FP236843; CAX61594.1; -; Genomic_DNA.
DR   RefSeq; WP_013204077.1; NC_014306.1.
DR   AlphaFoldDB; D8MXN7; -.
DR   SMR; D8MXN7; -.
DR   STRING; 634500.EbC_40630; -.
DR   EnsemblBacteria; CAX61594; CAX61594; EbC_40630.
DR   KEGG; ebi:EbC_40630; -.
DR   eggNOG; COG1289; Bacteria.
DR   HOGENOM; CLU_027647_0_0_6; -.
DR   OMA; MITQACE; -.
DR   OrthoDB; 1320135at2; -.
DR   Proteomes; UP000008793; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0046942; P:carboxylic acid transport; IEA:InterPro.
DR   HAMAP; MF_01545; AaeB; 1.
DR   InterPro; IPR006726; PHBA_efflux_AaeB/fusaric-R.
DR   InterPro; IPR023706; PHBA_efflux_pump_AaeB.
DR   PANTHER; PTHR30509:SF10; PTHR30509:SF10; 1.
DR   Pfam; PF04632; FUSC; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..652
FT                   /note="p-hydroxybenzoic acid efflux pump subunit AaeB"
FT                   /id="PRO_0000414003"
FT   TRANSMEM        8..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        34..54
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        64..84
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        88..108
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        118..138
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        149..169
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        367..387
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        404..424
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        429..449
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        453..473
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        480..500
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
SQ   SEQUENCE   652 AA;  72897 MW;  7FA513565F342FEC CRC64;
     MQWHRLRFPI KLTFAIVLSL LIGFHFNLET PRWAVMTACI VAGGTAFAAG GDPFSGALRH
     RGMLRIIGTF LGCIAALTIM IATIRAPALM MLLCCMWAGL CVWLSSLIKI ENSYALGLAG
     YTALIIVVSV DANGSVLLAP QFAVERCSEI IIGIVCAILA DMLFSPRSVK QDIDREIDAL
     LVDQYKLMQL CVAHGDKEEV DRLWTNLVRR TTALNGMRGN LMMESSRWQK IDERMRALNT
     LSLALITQAA ETYLIQDSRK EYVPPQFHIF FDKSVENIGD IHKRMKIMRR VITTSGSKNT
     PVTLQNWVVA ATRYLLLLKG IHTNSSISRI EREVLKDEPV VKMRSAESRH AMINGIRTFV
     ATAVGSLFWL WTGWASGSGA MVMLAVITAL AMRMPNPLMM AKDFLYGMIV AIPLGSLYYM
     VIMPSTQQSM LLLCISLGVM AFIGGILIQR RQIGTLGGLV GTINIITLDN PMTFNVTAFL
     DNALGQAIGC FLALLVILLI RDTSKARTGR ILLNRFMYAA VAAMSTNQAR RRENHLPALY
     HQLFMLLNIF PGDIDKFRIA LTLIIGHQRL RDADIPVNED LSAYHKQLRH TADQVIAART
     DAKRHRYFEQ LLAELDTYQG KLVHYDAPLN VTEPVKRLAN TLKKYQNTLI QI