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AAEB_MUSP7
ID   AAEB_MUSP7              Reviewed;         651 AA.
AC   C6C4L7;
DT   16-NOV-2011, integrated into UniProtKB/Swiss-Prot.
DT   01-SEP-2009, sequence version 1.
DT   03-AUG-2022, entry version 63.
DE   RecName: Full=p-hydroxybenzoic acid efflux pump subunit AaeB {ECO:0000255|HAMAP-Rule:MF_01545};
DE            Short=pHBA efflux pump protein B {ECO:0000255|HAMAP-Rule:MF_01545};
GN   Name=aaeB {ECO:0000255|HAMAP-Rule:MF_01545}; OrderedLocusNames=Dd703_3667;
OS   Musicola paradisiaca (strain Ech703) (Dickeya paradisiaca) (Dickeya
OS   dadantii).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Pectobacteriaceae; Musicola.
OX   NCBI_TaxID=579405;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ech703;
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C.,
RA   Han C., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N.,
RA   Balakrishnan V., Glasner J., Perna N.T.;
RT   "Complete sequence of Dickeya dadantii Ech703.";
RL   Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Forms an efflux pump with AaeA. Could function as a metabolic
CC       relief valve, allowing to eliminate certain compounds when they
CC       accumulate to high levels in the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01545}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01545}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01545}.
CC   -!- SIMILARITY: Belongs to the aromatic acid exporter ArAE (TC 2.A.85)
CC       family. {ECO:0000255|HAMAP-Rule:MF_01545}.
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DR   EMBL; CP001654; ACS87424.1; -; Genomic_DNA.
DR   RefSeq; WP_015855321.1; NC_012880.1.
DR   AlphaFoldDB; C6C4L7; -.
DR   SMR; C6C4L7; -.
DR   STRING; 579405.Dd703_3667; -.
DR   EnsemblBacteria; ACS87424; ACS87424; Dd703_3667.
DR   KEGG; dda:Dd703_3667; -.
DR   eggNOG; COG1289; Bacteria.
DR   HOGENOM; CLU_027647_0_0_6; -.
DR   OMA; MITQACE; -.
DR   Proteomes; UP000002734; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0046942; P:carboxylic acid transport; IEA:InterPro.
DR   HAMAP; MF_01545; AaeB; 1.
DR   InterPro; IPR006726; PHBA_efflux_AaeB/fusaric-R.
DR   InterPro; IPR023706; PHBA_efflux_pump_AaeB.
DR   PANTHER; PTHR30509:SF10; PTHR30509:SF10; 1.
DR   Pfam; PF04632; FUSC; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..651
FT                   /note="p-hydroxybenzoic acid efflux pump subunit AaeB"
FT                   /id="PRO_0000413999"
FT   TRANSMEM        11..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        41..61
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        65..85
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        91..111
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        117..137
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        150..170
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        367..387
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        404..424
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        428..448
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        454..474
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        480..500
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
SQ   SEQUENCE   651 AA;  71369 MW;  39F728A42552FFD9 CRC64;
     MNSSVFPRLR FACKLSLAVV LSLVLGFWFE METPRWAALT AAIVAAGPAF VAGGDPFSGA
     IRHRGLLRIL GTFIGCFGAL VIIMTTVRAP VVMLMLCCLW AGVCVWISSL VKTENSYVFA
     LAGYTALIII ITSQSSPRAI PQFAIERCSE IILGIVCVIL ADLVFSPRSV KQDVDRAIDD
     LLLGQYQLLQ RCVGRAATDD VDSCWHGLLR KTQAIGGMRN ILLMESSHWQ PAWRRMKTLL
     SQSWMMMTLA GEIGLMRRDG DCVVKGGLLM LLEQPVTTPG DLRRQLRQLR HLAASHSSRL
     PAPLVGWLAA SSRYQLLAAG IRTNARISQR ETEILEAETP VRASSAETHH ALINGLRTGV
     ATAVGCLFWL LTGWTSGSVC MVMLGVVTAL VMRLPNPLMA AKDFLIGTLI ALPLGAVMFM
     LVLPATQQSL LLLGLCIGVM TFVIGIEIQK RRLGSLGALA STINILVLDN PMTFNLSQFL
     DNAIGQIIGC VLALAVIMLI RDNSRARTGR TLLNRLVHGA IDGLSTRPAR CRENHLPALY
     QHLFLLINLF PGDMAKYRLA LSLIIVHQRL RQLDIPLSDT LAECHRQMRA TAARVAGAAG
     DTQRSRYFSQ LLTQMEEYRQ HLGEHQVADD IVAAVARLTA LLQRHQHALC D
 
 
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