AAEB_MUSP7
ID AAEB_MUSP7 Reviewed; 651 AA.
AC C6C4L7;
DT 16-NOV-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-SEP-2009, sequence version 1.
DT 03-AUG-2022, entry version 63.
DE RecName: Full=p-hydroxybenzoic acid efflux pump subunit AaeB {ECO:0000255|HAMAP-Rule:MF_01545};
DE Short=pHBA efflux pump protein B {ECO:0000255|HAMAP-Rule:MF_01545};
GN Name=aaeB {ECO:0000255|HAMAP-Rule:MF_01545}; OrderedLocusNames=Dd703_3667;
OS Musicola paradisiaca (strain Ech703) (Dickeya paradisiaca) (Dickeya
OS dadantii).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Pectobacteriaceae; Musicola.
OX NCBI_TaxID=579405;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ech703;
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C.,
RA Han C., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N.,
RA Balakrishnan V., Glasner J., Perna N.T.;
RT "Complete sequence of Dickeya dadantii Ech703.";
RL Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Forms an efflux pump with AaeA. Could function as a metabolic
CC relief valve, allowing to eliminate certain compounds when they
CC accumulate to high levels in the cell. {ECO:0000255|HAMAP-
CC Rule:MF_01545}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_01545}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_01545}.
CC -!- SIMILARITY: Belongs to the aromatic acid exporter ArAE (TC 2.A.85)
CC family. {ECO:0000255|HAMAP-Rule:MF_01545}.
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DR EMBL; CP001654; ACS87424.1; -; Genomic_DNA.
DR RefSeq; WP_015855321.1; NC_012880.1.
DR AlphaFoldDB; C6C4L7; -.
DR SMR; C6C4L7; -.
DR STRING; 579405.Dd703_3667; -.
DR EnsemblBacteria; ACS87424; ACS87424; Dd703_3667.
DR KEGG; dda:Dd703_3667; -.
DR eggNOG; COG1289; Bacteria.
DR HOGENOM; CLU_027647_0_0_6; -.
DR OMA; MITQACE; -.
DR Proteomes; UP000002734; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:0046942; P:carboxylic acid transport; IEA:InterPro.
DR HAMAP; MF_01545; AaeB; 1.
DR InterPro; IPR006726; PHBA_efflux_AaeB/fusaric-R.
DR InterPro; IPR023706; PHBA_efflux_pump_AaeB.
DR PANTHER; PTHR30509:SF10; PTHR30509:SF10; 1.
DR Pfam; PF04632; FUSC; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..651
FT /note="p-hydroxybenzoic acid efflux pump subunit AaeB"
FT /id="PRO_0000413999"
FT TRANSMEM 11..31
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT TRANSMEM 41..61
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT TRANSMEM 65..85
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT TRANSMEM 91..111
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT TRANSMEM 117..137
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT TRANSMEM 150..170
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT TRANSMEM 367..387
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT TRANSMEM 404..424
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT TRANSMEM 428..448
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT TRANSMEM 454..474
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT TRANSMEM 480..500
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
SQ SEQUENCE 651 AA; 71369 MW; 39F728A42552FFD9 CRC64;
MNSSVFPRLR FACKLSLAVV LSLVLGFWFE METPRWAALT AAIVAAGPAF VAGGDPFSGA
IRHRGLLRIL GTFIGCFGAL VIIMTTVRAP VVMLMLCCLW AGVCVWISSL VKTENSYVFA
LAGYTALIII ITSQSSPRAI PQFAIERCSE IILGIVCVIL ADLVFSPRSV KQDVDRAIDD
LLLGQYQLLQ RCVGRAATDD VDSCWHGLLR KTQAIGGMRN ILLMESSHWQ PAWRRMKTLL
SQSWMMMTLA GEIGLMRRDG DCVVKGGLLM LLEQPVTTPG DLRRQLRQLR HLAASHSSRL
PAPLVGWLAA SSRYQLLAAG IRTNARISQR ETEILEAETP VRASSAETHH ALINGLRTGV
ATAVGCLFWL LTGWTSGSVC MVMLGVVTAL VMRLPNPLMA AKDFLIGTLI ALPLGAVMFM
LVLPATQQSL LLLGLCIGVM TFVIGIEIQK RRLGSLGALA STINILVLDN PMTFNLSQFL
DNAIGQIIGC VLALAVIMLI RDNSRARTGR TLLNRLVHGA IDGLSTRPAR CRENHLPALY
QHLFLLINLF PGDMAKYRLA LSLIIVHQRL RQLDIPLSDT LAECHRQMRA TAARVAGAAG
DTQRSRYFSQ LLTQMEEYRQ HLGEHQVADD IVAAVARLTA LLQRHQHALC D