ID   AAEB_PANAM              Reviewed;         650 AA.
AC   D4GCB2;
DT   16-NOV-2011, integrated into UniProtKB/Swiss-Prot.
DT   18-MAY-2010, sequence version 1.
DT   03-AUG-2022, entry version 55.
DE   RecName: Full=p-hydroxybenzoic acid efflux pump subunit AaeB {ECO:0000255|HAMAP-Rule:MF_01545};
DE            Short=pHBA efflux pump protein B {ECO:0000255|HAMAP-Rule:MF_01545};
GN   Name=aaeB {ECO:0000255|HAMAP-Rule:MF_01545}; OrderedLocusNames=PANA_3556;
OS   Pantoea ananatis (strain LMG 20103).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Erwiniaceae; Pantoea.
OX   NCBI_TaxID=706191;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LMG 20103;
RX   PubMed=20348253; DOI=10.1128/jb.00060-10;
RA   De Maayer P., Chan W.Y., Venter S.N., Toth I.K., Birch P.R., Joubert F.,
RA   Coutinho T.A.;
RT   "Genome sequence of Pantoea ananatis LMG20103, the causative agent of
RT   Eucalyptus blight and dieback.";
RL   J. Bacteriol. 192:2936-2937(2010).
CC   -!- FUNCTION: Forms an efflux pump with AaeA. Could function as a metabolic
CC       relief valve, allowing to eliminate certain compounds when they
CC       accumulate to high levels in the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01545}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01545}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01545}.
CC   -!- SIMILARITY: Belongs to the aromatic acid exporter ArAE (TC 2.A.85)
CC       family. {ECO:0000255|HAMAP-Rule:MF_01545}.
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DR   EMBL; CP001875; ADD78723.1; -; Genomic_DNA.
DR   RefSeq; WP_013027423.1; NC_013956.2.
DR   AlphaFoldDB; D4GCB2; -.
DR   STRING; 706191.PANA_3556; -.
DR   PRIDE; D4GCB2; -.
DR   EnsemblBacteria; ADD78723; ADD78723; PANA_3556.
DR   KEGG; pam:PANA_3556; -.
DR   eggNOG; COG1289; Bacteria.
DR   HOGENOM; CLU_027647_0_0_6; -.
DR   OMA; MITQACE; -.
DR   OrthoDB; 1320135at2; -.
DR   BioCyc; PANA706191:PANA_RS18040-MON; -.
DR   Proteomes; UP000001702; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0046942; P:carboxylic acid transport; IEA:InterPro.
DR   HAMAP; MF_01545; AaeB; 1.
DR   InterPro; IPR006726; PHBA_efflux_AaeB/fusaric-R.
DR   InterPro; IPR023706; PHBA_efflux_pump_AaeB.
DR   PANTHER; PTHR30509:SF10; PTHR30509:SF10; 1.
DR   Pfam; PF04632; FUSC; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..650
FT                   /note="p-hydroxybenzoic acid efflux pump subunit AaeB"
FT                   /id="PRO_0000414004"
FT   TRANSMEM        7..27
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        32..52
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        61..81
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        87..107
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        115..135
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        148..168
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        365..385
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        402..422
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        426..446
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        450..470
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        478..498
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
SQ   SEQUENCE   650 AA;  72449 MW;  FC44A7099D214CC1 CRC64;
     MTEFLRFPIK LTFALVAALM IGFHLNLETP RWAVMTAGIV AGGTAFAAGG DPYSGALRYR
     GILRIIGTFI GCVAALVIMI ATVRAPVVML LLCCIWAGFC VWLSSLIKVE NSYALGLAGY
     TALIIVVTAN ASGGLTLVPQ YAVERCSEII LGILCAILAD MIFSPRSIKK VIDAEVDSLL
     VAHYRLLQLC VAHEDKEEVD KAWGALVRRT TALSSMRSQL MMESSRWQNT SRRLQMLNTL
     SLTMITQAAE TFLIQNSRPD YIATQYRVLM EKEAATAEDV HKRMKALRRL IAVSSKTVPE
     TLESWVEAAT EYQLLTHGIK SNGRITALEE GILQREVVIQ ARSAENHHAM INGVRTFVAT
     ALGSLFWLYT GWTSGSGCMV MLGVITALAM RMPNPLMMAK DFVYGMTVAV PLGALYFMYI
     LPNTQQSAVL LCIAIGLLGF ISGILIQRRQ IGTLGAMVGT INVLVLDNPM QFNFTQFIDN
     ALGQWIGSFV ALMVILLIRD KSKARTGRKL LNRFMYAAVS AMTTNQARRR ENHLPALYQQ
     LFLLLNLFPG DIDKYRIALT LIIGHQRLRA ADVPVNADLS AYHRQLRHTA DRIISVRSDE
     KRRYYFERLL KELDVYQHKL AHYDAPTSVT EPVTRLAEML KKYQNTLVQI