ID   AAEB_PECCP              Reviewed;         662 AA.
AC   C6DIM3;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-SEP-2009, sequence version 1.
DT   03-AUG-2022, entry version 66.
DE   RecName: Full=p-hydroxybenzoic acid efflux pump subunit AaeB {ECO:0000255|HAMAP-Rule:MF_01545};
DE            Short=pHBA efflux pump protein B {ECO:0000255|HAMAP-Rule:MF_01545};
GN   Name=aaeB {ECO:0000255|HAMAP-Rule:MF_01545}; OrderedLocusNames=PC1_0264;
OS   Pectobacterium carotovorum subsp. carotovorum (strain PC1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Pectobacteriaceae; Pectobacterium.
OX   NCBI_TaxID=561230;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PC1;
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D.,
RA   Goodwin L., Pitluck S., Munk A.C., Brettin T., Detter J.C., Han C.,
RA   Tapia R., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N.,
RA   Balakrishnan V., Glasner J., Perna N.T.;
RT   "Complete sequence of Pectobacterium carotovorum subsp. carotovorum PC1.";
RL   Submitted (JUL-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Forms an efflux pump with AaeA. Could function as a metabolic
CC       relief valve, allowing to eliminate certain compounds when they
CC       accumulate to high levels in the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01545}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01545}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01545}.
CC   -!- SIMILARITY: Belongs to the aromatic acid exporter ArAE (TC 2.A.85)
CC       family. {ECO:0000255|HAMAP-Rule:MF_01545}.
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DR   EMBL; CP001657; ACT11323.1; -; Genomic_DNA.
DR   RefSeq; WP_012772987.1; NC_012917.1.
DR   AlphaFoldDB; C6DIM3; -.
DR   SMR; C6DIM3; -.
DR   STRING; 561230.PC1_0264; -.
DR   EnsemblBacteria; ACT11323; ACT11323; PC1_0264.
DR   KEGG; pct:PC1_0264; -.
DR   eggNOG; COG1289; Bacteria.
DR   HOGENOM; CLU_027647_0_0_6; -.
DR   OMA; MITQACE; -.
DR   OrthoDB; 1320135at2; -.
DR   Proteomes; UP000002736; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0046942; P:carboxylic acid transport; IEA:InterPro.
DR   HAMAP; MF_01545; AaeB; 1.
DR   InterPro; IPR006726; PHBA_efflux_AaeB/fusaric-R.
DR   InterPro; IPR023706; PHBA_efflux_pump_AaeB.
DR   PANTHER; PTHR30509:SF10; PTHR30509:SF10; 1.
DR   Pfam; PF04632; FUSC; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..662
FT                   /note="p-hydroxybenzoic acid efflux pump subunit AaeB"
FT                   /id="PRO_1000215443"
FT   TRANSMEM        22..42
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        52..72
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        76..96
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        102..122
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        129..149
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        161..181
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        378..398
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        415..435
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        439..459
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        467..487
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        491..511
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
SQ   SEQUENCE   662 AA;  73058 MW;  2834B9B100309363 CRC64;
     MKTPSLTGPV FFTTPKFARL RFAFKLSFAI VLSLFLGFHL QLETPRWSVL TAAIVAAGPA
     FAAGGEPFSG AIRHRGMLRV VGTFIGCIGA LIIIIATVRA PVVMLMLCCI WAGLCTWVSS
     LVKVENAYVF GLAGYTTLII IVSTQGTPLL TPQFAVERCS EIVLGIVCAI LADLLFSPRS
     IKQDVDRSMG ELLVDQYRLL QLSMSGAEKE TIDAAWHALV RKTTALSGMR SSLMLESSRW
     QNSNRRLTSL HTQSLTMITQ ACETYLVLQD APTPVKSSLK LVLDQPVESF RDVHCRVKAL
     RHLIAADSRD VPPTLVSWVG AATRYLLLAK GVQTNGRITT IEADVLNSEV EIKAPSAETH
     HAMINGLRTG VATALGCLFW LSTGWTSGSV CMVMIAVVTS LAMRLPNPQM MAKDFLFGTI
     YALPLGALMF MFIMPSTQQS MLLLCLSLGA MAFFLGLEVQ KRRLGSLGAL ASTINILVLD
     NPMTFHISQF LDSAIGQIIG CFLALMVILL IRDNTKAHTG RTLLNRFVYG AVSALTTNTT
     RRKENHLPAL YQQLFLLLNR FPDDIAKYRL ALWLIIMHQR LRTLDIPQNA ALSAFHRQIR
     ATAEQVILAR RDTTRSRYFT QLLGELERYQ QMLTEQQLPA SVTAPVGRLT GILRDYQHAL
     SN