ID   AAEB_RAHSY              Reviewed;         652 AA.
AC   E8XWL7;
DT   16-NOV-2011, integrated into UniProtKB/Swiss-Prot.
DT   05-APR-2011, sequence version 1.
DT   03-AUG-2022, entry version 52.
DE   RecName: Full=p-hydroxybenzoic acid efflux pump subunit AaeB {ECO:0000255|HAMAP-Rule:MF_01545};
DE            Short=pHBA efflux pump protein B {ECO:0000255|HAMAP-Rule:MF_01545};
GN   Name=aaeB {ECO:0000255|HAMAP-Rule:MF_01545}; OrderedLocusNames=Rahaq_4004;
OS   Rahnella sp. (strain Y9602).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Rahnella.
OX   NCBI_TaxID=2703885;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Y9602;
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA   Lu M., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N.,
RA   Ivanova N., Ovchinnikova G., Pagani I., Sobecky P.A., Martinez R.J.,
RA   Woyke T.;
RT   "Complete sequence of chromosome of Rahnella sp. Y9602.";
RL   Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Forms an efflux pump with AaeA. Could function as a metabolic
CC       relief valve, allowing to eliminate certain compounds when they
CC       accumulate to high levels in the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01545}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01545}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01545}.
CC   -!- SIMILARITY: Belongs to the aromatic acid exporter ArAE (TC 2.A.85)
CC       family. {ECO:0000255|HAMAP-Rule:MF_01545}.
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DR   EMBL; CP002505; ADW75592.1; -; Genomic_DNA.
DR   RefSeq; WP_013577281.1; NC_015061.1.
DR   AlphaFoldDB; E8XWL7; -.
DR   SMR; E8XWL7; -.
DR   STRING; 741091.Rahaq_4004; -.
DR   PRIDE; E8XWL7; -.
DR   EnsemblBacteria; ADW75592; ADW75592; Rahaq_4004.
DR   KEGG; rah:Rahaq_4004; -.
DR   eggNOG; COG1289; Bacteria.
DR   HOGENOM; CLU_027647_0_0_6; -.
DR   OMA; MITQACE; -.
DR   OrthoDB; 1320135at2; -.
DR   Proteomes; UP000007257; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0046942; P:carboxylic acid transport; IEA:InterPro.
DR   HAMAP; MF_01545; AaeB; 1.
DR   InterPro; IPR006726; PHBA_efflux_AaeB/fusaric-R.
DR   InterPro; IPR023706; PHBA_efflux_pump_AaeB.
DR   PANTHER; PTHR30509:SF10; PTHR30509:SF10; 1.
DR   Pfam; PF04632; FUSC; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..652
FT                   /note="p-hydroxybenzoic acid efflux pump subunit AaeB"
FT                   /id="PRO_0000414006"
FT   TRANSMEM        11..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        41..61
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        65..85
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        91..111
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        118..138
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        368..388
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        405..425
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        430..450
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        455..475
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
FT   TRANSMEM        480..500
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01545"
SQ   SEQUENCE   652 AA;  71930 MW;  6B4E5DAB73E9B0C7 CRC64;
     MNSVLIPRVR FACKLTFAIL GALVLGFYLQ LETPRWSAMT AAIVTSGPAL AAGGEPFAGA
     IRHRGFLRVI GTFIGCIAAL VIVIATARAP VVMLLLCCIW AGVCTWWSSL VRIENSYALG
     LAGYTALIIV VTSASSPLQT PQFAVERCSE IVIGICCAIV ADLLFSPRSI KKDIDRAVSQ
     LMLDQFALMR ICVNSGTKEE IDKSWNNLVK STTALNGMRG SLMMESSRWQ RCNRRLKALH
     STSLSMITQA CETYLIMQSS PERVSPELKA LFAEPAENVA DVHRRLKQLR QMITGMHSDN
     VLMTVSAWTG AGTRALLLMK GIQTNSSISA IESGVLDGEV VVRPVSAERH HALVNGLRTF
     TATTIGCLMW LWTGWTSASG CVIIIAVVTS LAMRTPNPKG MAMDFIIGML LAIPVGSMMF
     MLIMPATQQS LFLLCLMLGI FTFFIGIEVT KRRLGMLGLL AGTINILVLS NPMVFNVTSF
     LDNAMGQAIG TVIAMAVLLI VRDKSREKTG RTLLNRFMSS AVSALTTKAY RRRENHLPAL
     YHQLNQLLVM FPNDIGKYRL ALMLIIAHQR MKLAEVPVND ELSAFHKKIR NTADHVVSAS
     GEGKRTYYYQ RLLKELGEYQ EKLVEYDAPL KVTEPVRRLT DMLQRYQHAF LA