QWRF6_ARATH
ID QWRF6_ARATH Reviewed; 442 AA.
AC Q5BPM6; Q6DYB8; Q9M1X6;
DT 16-OCT-2013, integrated into UniProtKB/Swiss-Prot.
DT 12-APR-2005, sequence version 1.
DT 03-AUG-2022, entry version 88.
DE RecName: Full=QWRF motif-containing protein 6;
GN Name=QWRF6; OrderedLocusNames=At3g60000; ORFNames=F24G16.270;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC STRAIN=cv. Columbia;
RA Underwood B.A., Xiao Y.-L., Moskal W.A. Jr., Monaghan E.L., Wang W.,
RA Redman J.C., Wu H.C., Utterback T., Town C.D.;
RL Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=20978221; DOI=10.1105/tpc.110.074781;
RA Albrecht V., Simkova K., Carrie C., Delannoy E., Giraud E., Whelan J.,
RA Small I.D., Apel K., Badger M.R., Pogson B.J.;
RT "The cytoskeleton and the peroxisomal-targeted snowy cotyledon3 protein are
RT required for chloroplast development in Arabidopsis.";
RL Plant Cell 22:3423-3438(2010).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q5BPM6-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q5BPM6-2; Sequence=VSP_053221;
CC -!- SIMILARITY: Belongs to the QWRF family. {ECO:0000305}.
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DR EMBL; AL138647; CAB75819.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE80000.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE80001.1; -; Genomic_DNA.
DR EMBL; AY630787; AAT67586.1; -; mRNA.
DR EMBL; AY924802; AAX23877.1; -; mRNA.
DR PIR; T47824; T47824.
DR RefSeq; NP_001118860.1; NM_001125388.1. [Q5BPM6-2]
DR RefSeq; NP_191559.2; NM_115863.4. [Q5BPM6-1]
DR AlphaFoldDB; Q5BPM6; -.
DR PaxDb; Q5BPM6; -.
DR PRIDE; Q5BPM6; -.
DR EnsemblPlants; AT3G60000.1; AT3G60000.1; AT3G60000. [Q5BPM6-1]
DR EnsemblPlants; AT3G60000.2; AT3G60000.2; AT3G60000. [Q5BPM6-2]
DR GeneID; 825170; -.
DR Gramene; AT3G60000.1; AT3G60000.1; AT3G60000. [Q5BPM6-1]
DR Gramene; AT3G60000.2; AT3G60000.2; AT3G60000. [Q5BPM6-2]
DR KEGG; ath:AT3G60000; -.
DR Araport; AT3G60000; -.
DR TAIR; locus:2080522; AT3G60000.
DR eggNOG; ENOG502R98H; Eukaryota.
DR OMA; IEECSMR; -.
DR PhylomeDB; Q5BPM6; -.
DR PRO; PR:Q5BPM6; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q5BPM6; baseline and differential.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005880; C:nuclear microtubule; IBA:GO_Central.
DR GO; GO:0008017; F:microtubule binding; IBA:GO_Central.
DR GO; GO:0051225; P:spindle assembly; IBA:GO_Central.
DR InterPro; IPR007573; QWRF.
DR Pfam; PF04484; QWRF; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Reference proteome.
FT CHAIN 1..442
FT /note="QWRF motif-containing protein 6"
FT /id="PRO_0000423627"
FT REGION 1..144
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 221..240
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 264..267
FT /note="QWRF motif"
FT COMPBIAS 33..74
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 78..92
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 93..112
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 430..442
FT /note="VLNLSLHKLKNVL -> IEECSMRSQLIQQTTKEESSSK (in isoform
FT 2)"
FT /evidence="ECO:0000305"
FT /id="VSP_053221"
FT CONFLICT 134..135
FT /note="PP -> LS (in Ref. 3; AAT67586)"
FT /evidence="ECO:0000305"
FT CONFLICT 148
FT /note="T -> I (in Ref. 3; AAT67586)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 442 AA; 49075 MW; 91BF7E43C6C18B7D CRC64;
MEAKTSGPKQ IQPSTPAPPP STRRPRVREV SSRFMSPVTS SSSSAGDLHS LTCNSPKQHH
LQHHQIQRSV SAQRLRRQLK MADGDENRSS ETAARSLDSP FTLSQSRKSS KPSHLKPLNE
NSHRLETPTP MVPPPPSRSR LSQQRLPTAT RLLQLSGISA CYEKEGIINI QEKPKSNGSD
QFPTLSCRTH LKVFNNPVPS SLNRSVSSPS SSCNVRESSS FSRLGLPLPP MAPKVPADTK
KQRKVTEQLE DVHSLKLLHN RYLQWRFANA NAQVKTQTHK TQTETMIHSF GSKISELHDS
VQRKRIELQR LLKTKALLAI TESQTPCLEQ WSAIEEEYST SVSQTIQAFS NASLRLPLDG
DIMVDSKQLG DGLVAASKIV DGITQNVGNY MPKAKEMESL LSELTRVARS ERSLTENCVV
ALLKTQASQV LNLSLHKLKN VL
