R212B_MOUSE
ID R212B_MOUSE Reviewed; 297 AA.
AC D3Z423; D3Z2T6;
DT 15-JUN-2010, integrated into UniProtKB/Swiss-Prot.
DT 20-APR-2010, sequence version 1.
DT 03-AUG-2022, entry version 60.
DE RecName: Full=RING finger protein 212B;
GN Name=Rnf212b; Synonyms=Gm10332;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AC116591; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR CCDS; CCDS88665.1; -.
DR RefSeq; XP_006519928.1; XM_006519865.2.
DR RefSeq; XP_011243591.1; XM_011245289.2.
DR AlphaFoldDB; D3Z423; -.
DR SMR; D3Z423; -.
DR PhosphoSitePlus; D3Z423; -.
DR PRIDE; D3Z423; -.
DR ProteomicsDB; 255061; -.
DR Antibodypedia; 64489; 5 antibodies from 5 providers.
DR Ensembl; ENSMUST00000218311; ENSMUSP00000151344; ENSMUSG00000112858.
DR GeneID; 102632837; -.
DR CTD; 100507650; -.
DR MGI; MGI:3642276; Gm10332.
DR VEuPathDB; HostDB:ENSMUSG00000112858; -.
DR GeneTree; ENSGT00740000115581; -.
DR InParanoid; D3Z423; -.
DR OMA; MQEAQQT; -.
DR OrthoDB; 1325661at2759; -.
DR PhylomeDB; D3Z423; -.
DR ChiTaRS; Rnf212b; mouse.
DR PRO; PR:D3Z423; -.
DR Proteomes; UP000000589; Chromosome 14.
DR RNAct; D3Z423; protein.
DR Bgee; ENSMUSG00000112858; Expressed in spermatid and 17 other tissues.
DR ExpressionAtlas; D3Z423; baseline and differential.
DR GO; GO:0000795; C:synaptonemal complex; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0019789; F:SUMO transferase activity; IBA:GO_Central.
DR GO; GO:0007129; P:homologous chromosome pairing at meiosis; IBA:GO_Central.
DR GO; GO:0016925; P:protein sumoylation; IBA:GO_Central.
DR GO; GO:0007131; P:reciprocal meiotic recombination; IEA:InterPro.
DR InterPro; IPR042123; Zip3/RNF212-like.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR22663; PTHR22663; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
PE 4: Predicted;
KW Coiled coil; Metal-binding; Reference proteome; Zinc; Zinc-finger.
FT CHAIN 1..297
FT /note="RING finger protein 212B"
FT /id="PRO_0000395110"
FT ZN_FING 6..40
FT /note="RING-type"
FT REGION 152..179
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 198..269
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 87..136
FT /evidence="ECO:0000255"
FT COMPBIAS 202..238
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 247..269
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 297 AA; 32990 MW; 7042DCBEF7B6514A CRC64;
MDWFHCNQCF RKDGAHFFVT SCGHIFCKKC MTLEKCAVCG NLCKHLALSD NLKPQEKKFF
KSPVETALQC FSHISQVWCF QKKQTDLLIA FYKDRITKLE AAVKEAQEMA ASQNKELSAL
RKENGELKKI LDILKGSPSC YYGSRLTTPR PVGITSPSQS VAPRPSSHHS SQVVSRSSSM
ESIPYTVAGM GHVEQGSRGL HVRSTPGDSY TETPSPASTH SLSYRPSSAS SGQGVSFRPF
FSGDSGHTRV LTPNNSGRRE SRTTPESLPG FQLPVLQTFY QQRQMGLARK DGWNISR
