R23A1_CAEEL
ID R23A1_CAEEL Reviewed; 147 AA.
AC P48162;
DT 01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1996, sequence version 1.
DT 03-AUG-2022, entry version 139.
DE RecName: Full=60S ribosomal protein L23a 1;
GN Name=rpl-25.1; ORFNames=F55D10.2;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- FUNCTION: This protein binds to a specific region on the 26S rRNA.
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL23 family.
CC {ECO:0000305}.
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DR EMBL; FO080828; CCD67088.1; -; Genomic_DNA.
DR PIR; T16456; T16456.
DR RefSeq; NP_508808.1; NM_076407.5.
DR AlphaFoldDB; P48162; -.
DR SMR; P48162; -.
DR BioGRID; 45683; 102.
DR DIP; DIP-24598N; -.
DR IntAct; P48162; 1.
DR STRING; 6239.F55D10.2; -.
DR EPD; P48162; -.
DR PaxDb; P48162; -.
DR PeptideAtlas; P48162; -.
DR EnsemblMetazoa; F55D10.2.1; F55D10.2.1; WBGene00004438.
DR GeneID; 180748; -.
DR KEGG; cel:CELE_F55D10.2; -.
DR UCSC; F55D10.2.1; c. elegans.
DR CTD; 180748; -.
DR WormBase; F55D10.2; CE02777; WBGene00004438; rpl-25.1.
DR eggNOG; KOG1751; Eukaryota.
DR GeneTree; ENSGT00970000196251; -.
DR HOGENOM; CLU_037562_0_2_1; -.
DR InParanoid; P48162; -.
DR OMA; VHFRRPV; -.
DR OrthoDB; 1436090at2759; -.
DR PhylomeDB; P48162; -.
DR Reactome; R-CEL-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR Reactome; R-CEL-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR Reactome; R-CEL-6791226; Major pathway of rRNA processing in the nucleolus and cytosol.
DR Reactome; R-CEL-72689; Formation of a pool of free 40S subunits.
DR Reactome; R-CEL-72706; GTP hydrolysis and joining of the 60S ribosomal subunit.
DR Reactome; R-CEL-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR Reactome; R-CEL-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR PRO; PR:P48162; -.
DR Proteomes; UP000001940; Chromosome X.
DR Bgee; WBGene00004438; Expressed in larva and 4 other tissues.
DR GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR GO; GO:0000027; P:ribosomal large subunit assembly; IBA:GO_Central.
DR GO; GO:0006412; P:translation; IEA:InterPro.
DR Gene3D; 3.30.70.330; -; 1.
DR HAMAP; MF_01369_A; Ribosomal_L23_A; 1.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR012678; Ribosomal_L23/L15e_core_dom_sf.
DR InterPro; IPR001014; Ribosomal_L23/L25_CS.
DR InterPro; IPR005633; Ribosomal_L23/L25_N.
DR InterPro; IPR013025; Ribosomal_L25/23.
DR PANTHER; PTHR11620; PTHR11620; 1.
DR Pfam; PF00276; Ribosomal_L23; 1.
DR Pfam; PF03939; Ribosomal_L23eN; 1.
DR SUPFAM; SSF54189; SSF54189; 1.
DR PROSITE; PS00050; RIBOSOMAL_L23; 1.
PE 3: Inferred from homology;
KW Reference proteome; Ribonucleoprotein; Ribosomal protein; RNA-binding;
KW rRNA-binding.
FT CHAIN 1..147
FT /note="60S ribosomal protein L23a 1"
FT /id="PRO_0000129470"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 147 AA; 16697 MW; 1F3FF0088C453955 CRC64;
MAPSAPAKTA KALDAKKKVV KGKRTTHRRQ VRTSVHFRRP VTLKTARQAR FPRKSAPKTS
KMDHFRIIQH PLTTESAMKK IEEHNTLVFI VSNDANKYQI KDAVHKLYNV QALKVNTLIT
PLQQKKAYVR LTADYDALDV ANKIGVI
