R3HD2_BOVIN
ID R3HD2_BOVIN Reviewed; 989 AA.
AC A0JNC2;
DT 12-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT 12-DEC-2006, sequence version 1.
DT 03-AUG-2022, entry version 68.
DE RecName: Full=R3H domain-containing protein 2;
GN Name=R3HDM2;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Hereford; TISSUE=Thalamus;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
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DR EMBL; BC126608; AAI26609.1; -; mRNA.
DR RefSeq; NP_001071502.1; NM_001078034.1.
DR AlphaFoldDB; A0JNC2; -.
DR BMRB; A0JNC2; -.
DR SMR; A0JNC2; -.
DR STRING; 9913.ENSBTAP00000024431; -.
DR iPTMnet; A0JNC2; -.
DR PaxDb; A0JNC2; -.
DR PRIDE; A0JNC2; -.
DR Ensembl; ENSBTAT00000024431; ENSBTAP00000024431; ENSBTAG00000018361.
DR GeneID; 613499; -.
DR KEGG; bta:613499; -.
DR CTD; 22864; -.
DR VEuPathDB; HostDB:ENSBTAG00000018361; -.
DR VGNC; VGNC:106430; R3HDM2.
DR eggNOG; KOG2953; Eukaryota.
DR GeneTree; ENSGT00940000155609; -.
DR InParanoid; A0JNC2; -.
DR OMA; KRRQIFX; -.
DR OrthoDB; 137913at2759; -.
DR Proteomes; UP000009136; Chromosome 5.
DR Bgee; ENSBTAG00000018361; Expressed in granulosa cell and 105 other tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR Gene3D; 3.30.1370.50; -; 1.
DR InterPro; IPR001374; R3H_dom.
DR InterPro; IPR036867; R3H_dom_sf.
DR InterPro; IPR024771; SUZ.
DR Pfam; PF01424; R3H; 1.
DR Pfam; PF12752; SUZ; 1.
DR SMART; SM00393; R3H; 1.
DR SUPFAM; SSF82708; SSF82708; 1.
DR PROSITE; PS51061; R3H; 1.
DR PROSITE; PS51673; SUZ; 1.
PE 2: Evidence at transcript level;
KW Nucleus; Phosphoprotein; Reference proteome.
FT CHAIN 1..989
FT /note="R3H domain-containing protein 2"
FT /id="PRO_0000290032"
FT DOMAIN 169..232
FT /note="R3H"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00382"
FT DOMAIN 233..303
FT /note="SUZ"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01009"
FT REGION 23..71
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 106..147
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 267..288
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 306..390
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 416..479
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 493..524
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 674..738
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 751..793
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 848..867
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 23..59
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 106..142
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 316..382
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 416..430
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 439..479
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 674..694
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 757..793
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 37
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q9Y2K5"
FT MOD_RES 143
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q80TM6"
FT MOD_RES 344
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q9Y2K5"
FT MOD_RES 347
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q80TM6"
FT MOD_RES 363
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q9Y2K5"
FT MOD_RES 866
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q9Y2K5"
FT MOD_RES 868
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q9Y2K5"
FT MOD_RES 869
FT /note="Phosphothreonine"
FT /evidence="ECO:0000250|UniProtKB:Q80TM6"
FT MOD_RES 873
FT /note="Phosphothreonine"
FT /evidence="ECO:0000250|UniProtKB:Q80TM6"
SQ SEQUENCE 989 AA; 108712 MW; E253887F3CD4E5D2 CRC64;
MSNSNTTQET LEIMKESEKK LVEESVNKNK FISKTPSKEE IEKESEDTSL RQETQRRTSN
HGHARKRAKS NSKLKLVRSL AVCEESSAPF VDGPLETQDI IQLHISCPSD KEEEKSTKDV
SEKEDKDKNK EKVPRRMLSR DSSQEYTDST GIDLHEFLVN TLKKNPRDRM MLLKLEQEIL
DFINDNNNQF KKFPQMTSYH RMLLHRVAAY FGMDHNVDQT GKAVIINKTS NTRIPEQRFS
EHIKDEKNTE FQQRFILKRD DASMDRDDNQ IRVPLQDGRR SKSIEEREEE YQRVRERIFA
RETGQNGYLN DIRGNREGLS RTSSSRQSST DSELKSLEPR PWSSTDSDGS VRSMRPPVTK
ASSFSGISIL TRGDSIGSSK GGSAGRISRP GMALGAPEVC NQVTSSQSVR GLLPCTAQQQ
QQQQQQLPAL PPTPQQQPPL NNHMISQADD LSNPFGQMSL SRQGSTEAAD PSSALFQPPL
ISQHPQQTSF IMASTGQPLP TSNYSTSSHA PPTQQVLPPQ GYMQPPQQIQ VSYYSPGQYP
NSNQQYRPLS HPVAYSPQRG QQLPQPSQQP GLQPMMPNQQ QAAYQGMIGV QQPQNQGLLS
NQRSGMGGQM QGLVVQYTPL PSYQVPVGND SQNVVQPPFQ QPMLVPASQS VQGALPAGGV
PVYYSMIPPA QQNGTSPSVG FLQPPGSEQY QMPQSPSPCS PPQMPQQYSG VSPSGPGVVV
MQLNVPNGPQ PPQNPSMVQW SHCKYYSMDQ RGQKPGDLYS PESSPQANTQ MSSSPVTSPT
QSPAPSPVTS LSNVCTGLSP LPVLTQFPRP GGPAQGDGRY SLLGQPLQYN LSICPPLLHG
QSAYSVHQGQ SGLKHGNRSK RQALKSASTD LGTTDVVLGR VLEVTDLPEG ITRTEADKLF
TQLAMSGAKI QWLKDAQGLP GGGGGDNGGT AENGRHSDLA ALYTIVAVFP SPLAAQNASL
RLNNSVSRFK LRVAKKNYDL RILERASSQ
