R9BPA_XENLA
ID R9BPA_XENLA Reviewed; 237 AA.
AC Q5XHI3;
DT 15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 23-NOV-2004, sequence version 1.
DT 03-AUG-2022, entry version 42.
DE RecName: Full=Regulator of G-protein signaling 9-binding protein A;
DE AltName: Full=RGS9-anchoring protein A;
GN Name=rgs9bp-a;
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Embryo;
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Regulator of G protein-coupled receptor (GPCR) signaling.
CC Probably acts by regulating the activity of some 'R7' family protein
CC (RGS6, RGS7, RGS9 and/or RGS11).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Single-pass type IV
CC membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the RGS7BP/RGS9BP family. {ECO:0000305}.
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DR EMBL; BC084074; AAH84074.1; -; mRNA.
DR RefSeq; NP_001088166.1; NM_001094697.1.
DR AlphaFoldDB; Q5XHI3; -.
DR SMR; Q5XHI3; -.
DR DNASU; 494990; -.
DR GeneID; 494990; -.
DR KEGG; xla:494990; -.
DR CTD; 494990; -.
DR Xenbase; XB-GENE-1011616; rgs9bp.S.
DR OrthoDB; 1602757at2759; -.
DR Proteomes; UP000186698; Chromosome 4S.
DR Bgee; 494990; Expressed in camera-type eye and 15 other tissues.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.
DR InterPro; IPR026512; RGS7BP/RGS9BP.
DR InterPro; IPR026513; RGS9BP.
DR PANTHER; PTHR21029; PTHR21029; 1.
DR PANTHER; PTHR21029:SF1; PTHR21029:SF1; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; Membrane; Reference proteome; Signal transduction inhibitor;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..237
FT /note="Regulator of G-protein signaling 9-binding protein
FT A"
FT /id="PRO_0000287590"
FT TOPO_DOM 1..212
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 213..233
FT /note="Helical; Anchor for type IV membrane protein"
FT /evidence="ECO:0000255"
FT TOPO_DOM 234..237
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT COILED 29..58
FT /evidence="ECO:0000255"
SQ SEQUENCE 237 AA; 26197 MW; 7D4563E66ADC9377 CRC64;
MLKEECKALL DALNKVTGCY RHLVLTIGGT SDSQNLREEL KKTRQKAQEL AVANRNTLTS
TLKDHRLTKE DKAEFERLWV IFSTCMDILE TDMRRALVLG QEFPLNIPKK HLIQTGMSGG
TSGVAARAMS AQNMRYEAEH NIDVMDLKDL ENEINLMGEM MYEMEMKVSV PQWTVEAKQD
PGAELKSIMS AGASSPGIIS LDAHKSICDL SKILAGVVFS AVLIIAIVLA VCVVKLS