R9BP_XENTR
ID R9BP_XENTR Reviewed; 265 AA.
AC Q5M8K0;
DT 15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-2005, sequence version 1.
DT 03-AUG-2022, entry version 72.
DE RecName: Full=Regulator of G-protein signaling 9-binding protein;
DE AltName: Full=RGS9-anchoring protein;
GN Name=rgs9bp;
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Regulator of G protein-coupled receptor (GPCR) signaling.
CC Probably acts by regulating the activity of some 'R7' family protein
CC (RGS6, RGS7, RGS9 and/or RGS11).
CC -!- SIMILARITY: Belongs to the RGS7BP/RGS9BP family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BC087990; AAH87990.1; -; mRNA.
DR RefSeq; NP_001011277.1; NM_001011277.1.
DR AlphaFoldDB; Q5M8K0; -.
DR SMR; Q5M8K0; -.
DR PaxDb; Q5M8K0; -.
DR DNASU; 496730; -.
DR Ensembl; ENSXETT00000032548; ENSXETP00000032548; ENSXETG00000014880.
DR GeneID; 496730; -.
DR KEGG; xtr:496730; -.
DR CTD; 496730; -.
DR Xenbase; XB-GENE-5936529; rgs9bpl.
DR eggNOG; ENOG502RXQ0; Eukaryota.
DR HOGENOM; CLU_093021_0_0_1; -.
DR InParanoid; Q5M8K0; -.
DR OMA; CFQQLVA; -.
DR OrthoDB; 1602757at2759; -.
DR PhylomeDB; Q5M8K0; -.
DR TreeFam; TF331562; -.
DR Proteomes; UP000008143; Chromosome 10.
DR Proteomes; UP000790000; Unplaced.
DR Bgee; ENSXETG00000014880; Expressed in brain and 13 other tissues.
DR GO; GO:0043005; C:neuron projection; IBA:GO_Central.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IBA:GO_Central.
DR GO; GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.
DR InterPro; IPR026512; RGS7BP/RGS9BP.
DR InterPro; IPR026513; RGS9BP.
DR PANTHER; PTHR21029; PTHR21029; 1.
DR PANTHER; PTHR21029:SF5; PTHR21029:SF5; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; Reference proteome; Signal transduction inhibitor.
FT CHAIN 1..265
FT /note="Regulator of G-protein signaling 9-binding protein"
FT /id="PRO_0000287593"
FT REGION 1..37
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 168..187
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 70..92
FT /evidence="ECO:0000255"
SQ SEQUENCE 265 AA; 29518 MW; 5DA3AD23DDB24F04 CRC64;
MAAPEVSSAG PNMLHPNSRT LTLRGKRGHA AEDSSQGAVS DCKKMHSSLN KVTACYRQLV
LCVGGTSDCT RLREELEESR KKAFDLSTDL SNTLMVLLMN EGVSQEDRVE LERIWVLFLS
TLEFFQQDLC KAHHLCQLFP LHGRRKRLVN TGVIGKTSEV AYRARNIKSP SSSRMHENQQ
RTERPCSPDL AGQIEHMERM LHDMQMKVSI PIWTVEATEE AWAEVASTCD LDECSDNEIL
AGEDITSRGC CAHGQSLPGP LCMVS