RA1L3_HUMAN
ID RA1L3_HUMAN Reviewed; 275 AA.
AC A0A2R8Y4L2;
DT 23-FEB-2022, integrated into UniProtKB/Swiss-Prot.
DT 20-JUN-2018, sequence version 1.
DT 03-AUG-2022, entry version 20.
DE RecName: Full=Heterogeneous nuclear ribonucleoprotein A1-like 3 {ECO:0000305};
DE AltName: Full=Heterogeneous nuclear ribonucleoprotein A1 pseudogene 48 {ECO:0000312|HGNC:HGNC:48778};
GN Name=HNRNPA1L3 {ECO:0000312|HGNC:HGNC:48778};
GN Synonyms=HNRNPA1P48 {ECO:0000312|HGNC:HGNC:48778};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15616553; DOI=10.1038/nature03187;
RA Martin J., Han C., Gordon L.A., Terry A., Prabhakar S., She X., Xie G.,
RA Hellsten U., Chan Y.M., Altherr M., Couronne O., Aerts A., Bajorek E.,
RA Black S., Blumer H., Branscomb E., Brown N.C., Bruno W.J., Buckingham J.M.,
RA Callen D.F., Campbell C.S., Campbell M.L., Campbell E.W., Caoile C.,
RA Challacombe J.F., Chasteen L.A., Chertkov O., Chi H.C., Christensen M.,
RA Clark L.M., Cohn J.D., Denys M., Detter J.C., Dickson M.,
RA Dimitrijevic-Bussod M., Escobar J., Fawcett J.J., Flowers D., Fotopulos D.,
RA Glavina T., Gomez M., Gonzales E., Goodstein D., Goodwin L.A., Grady D.L.,
RA Grigoriev I., Groza M., Hammon N., Hawkins T., Haydu L., Hildebrand C.E.,
RA Huang W., Israni S., Jett J., Jewett P.B., Kadner K., Kimball H.,
RA Kobayashi A., Krawczyk M.-C., Leyba T., Longmire J.L., Lopez F., Lou Y.,
RA Lowry S., Ludeman T., Manohar C.F., Mark G.A., McMurray K.L., Meincke L.J.,
RA Morgan J., Moyzis R.K., Mundt M.O., Munk A.C., Nandkeshwar R.D.,
RA Pitluck S., Pollard M., Predki P., Parson-Quintana B., Ramirez L., Rash S.,
RA Retterer J., Ricke D.O., Robinson D.L., Rodriguez A., Salamov A.,
RA Saunders E.H., Scott D., Shough T., Stallings R.L., Stalvey M.,
RA Sutherland R.D., Tapia R., Tesmer J.G., Thayer N., Thompson L.S., Tice H.,
RA Torney D.C., Tran-Gyamfi M., Tsai M., Ulanovsky L.E., Ustaszewska A.,
RA Vo N., White P.S., Williams A.L., Wills P.L., Wu J.-R., Wu K., Yang J.,
RA DeJong P., Bruce D., Doggett N.A., Deaven L., Schmutz J., Grimwood J.,
RA Richardson P., Rokhsar D.S., Eichler E.E., Gilna P., Lucas S.M.,
RA Myers R.M., Rubin E.M., Pennacchio L.A.;
RT "The sequence and analysis of duplication-rich human chromosome 16.";
RL Nature 432:988-994(2004).
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DR EMBL; AC084058; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2R8Y4L2; -.
DR SMR; A0A2R8Y4L2; -.
DR Ensembl; ENST00000565308.2; ENSP00000493805.1; ENSG00000224578.5.
DR GeneCards; HNRNPA1P48; -.
DR HGNC; HGNC:48778; HNRNPA1L3.
DR VEuPathDB; HostDB:ENSG00000224578; -.
DR GeneTree; ENSGT00950000183123; -.
DR OMA; SAFTKHF; -.
DR ChiTaRS; HNRNPA1P48; human.
DR Proteomes; UP000005640; Chromosome 16.
DR Bgee; ENSG00000224578; Expressed in ganglionic eminence and 105 other tissues.
DR GO; GO:0005654; C:nucleoplasm; IDA:HPA.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR CDD; cd12580; RRM2_hnRNPA1; 1.
DR Gene3D; 3.30.70.330; -; 2.
DR InterPro; IPR021662; HnRNPA1_C.
DR InterPro; IPR034803; hnRNPA1_RRM2.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR Pfam; PF11627; HnRNPA1; 1.
DR Pfam; PF00076; RRM_1; 2.
DR SMART; SM00360; RRM; 1.
DR SUPFAM; SSF54928; SSF54928; 2.
DR PROSITE; PS50102; RRM; 2.
PE 4: Predicted;
KW Reference proteome; Repeat; RNA-binding.
FT CHAIN 1..275
FT /note="Heterogeneous nuclear ribonucleoprotein A1-like 3"
FT /id="PRO_0000454745"
FT DOMAIN 1..52
FT /note="RRM 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT DOMAIN 60..139
FT /note="RRM 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT REGION 137..173
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 221..275
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 139..154
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 258..275
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 275 AA; 29174 MW; FDCC03BACE93A134 CRC64;
MRDPNTKRSR GFGFVTYATV EEVDAAMNAR PHKVDGRVVE PKRAVSREDS QRPDAHLTVK
KIFVGGIKED TEEHHLRDYF EQYGKIEVIE IMTDRGSGKK RGFAFVTFDD HDSVDKIVIQ
KYHTVNGHNC EVRKALSKQE MASASSSQRG RSGSGNFGGG RGGGFGGNDN FGRGGNFSGR
GGFGGSRGGG GYGGSGDGYN GFGNDGSNFG GGGSYNDFGN YNNQSSNFGP MKGGNFEGRS
SGPHGGGGQY FAKPRNQGGY GGSSSSSSYG SGRRF
