ID   RAA2B_ARATH             Reviewed;         214 AA.
AC   Q9LNW1;
DT   03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   03-MAY-2011, sequence version 2.
DT   03-AUG-2022, entry version 134.
DE   RecName: Full=Ras-related protein RABA2b;
DE            Short=AtRABA2b;
GN   Name=RABA2B; OrderedLocusNames=At1g07410; ORFNames=F22G5.24;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130712; DOI=10.1038/35048500;
RA   Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA   Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA   Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA   Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA   Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA   Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA   Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA   Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA   Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA   Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA   Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA   Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA   Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA   Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA   Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT   "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL   Nature 408:816-820(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=12644670; DOI=10.1104/pp.013052;
RA   Vernoud V., Horton A.C., Yang Z., Nielsen E.;
RT   "Analysis of the small GTPase gene superfamily of Arabidopsis.";
RL   Plant Physiol. 131:1191-1208(2003).
RN   [4]
RP   SUBCELLULAR LOCATION, AND TISSUE SPECIFICITY.
RX   PubMed=18239134; DOI=10.1105/tpc.107.052001;
RA   Chow C.M., Neto H., Foucart C., Moore I.;
RT   "Rab-A2 and Rab-A3 GTPases define a trans-Golgi endosomal membrane domain
RT   in Arabidopsis that contributes substantially to the cell plate.";
RL   Plant Cell 20:101-123(2008).
CC   -!- FUNCTION: Intracellular vesicle trafficking and protein transport.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Endosome membrane {ECO:0000269|PubMed:18239134}.
CC       Golgi apparatus, trans-Golgi network membrane
CC       {ECO:0000305|PubMed:18239134}; Lipid-anchor
CC       {ECO:0000305|PubMed:18239134}. Note=During cytokinesis located to the
CC       growing margins of the cell plate.
CC   -!- TISSUE SPECIFICITY: Expressed in root tips.
CC       {ECO:0000269|PubMed:18239134}.
CC   -!- SIMILARITY: Belongs to the small GTPase superfamily. Rab family.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAF79570.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AC022464; AAF79570.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002684; AEE28121.1; -; Genomic_DNA.
DR   PIR; A86209; A86209.
DR   RefSeq; NP_172221.1; NM_100615.3.
DR   AlphaFoldDB; Q9LNW1; -.
DR   SMR; Q9LNW1; -.
DR   STRING; 3702.AT1G07410.1; -.
DR   iPTMnet; Q9LNW1; -.
DR   PaxDb; Q9LNW1; -.
DR   PRIDE; Q9LNW1; -.
DR   ProteomicsDB; 236557; -.
DR   EnsemblPlants; AT1G07410.1; AT1G07410.1; AT1G07410.
DR   GeneID; 837253; -.
DR   Gramene; AT1G07410.1; AT1G07410.1; AT1G07410.
DR   KEGG; ath:AT1G07410; -.
DR   Araport; AT1G07410; -.
DR   TAIR; locus:2024992; AT1G07410.
DR   eggNOG; KOG0087; Eukaryota.
DR   HOGENOM; CLU_041217_23_0_1; -.
DR   InParanoid; Q9LNW1; -.
DR   OMA; NNKRPCC; -.
DR   OrthoDB; 1133775at2759; -.
DR   PRO; PR:Q9LNW1; -.
DR   Proteomes; UP000006548; Chromosome 1.
DR   ExpressionAtlas; Q9LNW1; baseline and differential.
DR   Genevisible; Q9LNW1; AT.
DR   GO; GO:0009504; C:cell plate; IDA:TAIR.
DR   GO; GO:0005768; C:endosome; IDA:TAIR.
DR   GO; GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central.
DR   GO; GO:0005886; C:plasma membrane; HDA:TAIR.
DR   GO; GO:0005525; F:GTP binding; IBA:GO_Central.
DR   GO; GO:0003924; F:GTPase activity; IBA:GO_Central.
DR   GO; GO:0042546; P:cell wall biogenesis; IMP:TAIR.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005225; Small_GTP-bd_dom.
DR   InterPro; IPR001806; Small_GTPase.
DR   Pfam; PF00071; Ras; 1.
DR   SMART; SM00174; RHO; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00231; small_GTP; 1.
DR   PROSITE; PS51419; RAB; 1.
PE   2: Evidence at transcript level;
KW   Endosome; Golgi apparatus; GTP-binding; Lipoprotein; Membrane;
KW   Nucleotide-binding; Prenylation; Protein transport; Reference proteome;
KW   Transport.
FT   CHAIN           1..214
FT                   /note="Ras-related protein RABA2b"
FT                   /id="PRO_0000407341"
FT   MOTIF           41..49
FT                   /note="Effector region"
FT                   /evidence="ECO:0000250"
FT   BINDING         19..26
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250"
FT   BINDING         67..71
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250"
FT   BINDING         125..128
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250"
FT   BINDING         155..156
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250"
FT   LIPID           211
FT                   /note="S-geranylgeranyl cysteine"
FT                   /evidence="ECO:0000250"
FT   LIPID           212
FT                   /note="S-geranylgeranyl cysteine"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   214 AA;  23689 MW;  4CC8ED2E3160D920 CRC64;
     MANRIDHEYD YLFKIVLIGD SGVGKSNILS RFTRNEFCLE SKSTIGVEFA TRTLQVEGKT
     VKAQIWDTAG QERYRAITSA YYRGAVGALL VYDITKRQTF ENVLRWLREL RDHADSNIVI
     MMAGNKSDLN HLRSVADEDG RSLAEKEGLS FLETSALEAT NIEKAFQTIL SEIYHIISKK
     ALAAQEAAGN LPGQGTAINI SDSSATNRKG CCST