RAA2D_ARATH
ID RAA2D_ARATH Reviewed; 217 AA.
AC Q9FIF9;
DT 03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 132.
DE RecName: Full=Ras-related protein RABA2d;
DE Short=AtRABA2d;
GN Name=RABA2D; OrderedLocusNames=At5g59150; ORFNames=MNC17.6;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10048488; DOI=10.1093/dnares/5.6.379;
RA Asamizu E., Sato S., Kaneko T., Nakamura Y., Kotani H., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. VIII. Sequence
RT features of the regions of 1,081,958 bp covered by seventeen physically
RT assigned P1 and TAC clones.";
RL DNA Res. 5:379-391(1998).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=12644670; DOI=10.1104/pp.013052;
RA Vernoud V., Horton A.C., Yang Z., Nielsen E.;
RT "Analysis of the small GTPase gene superfamily of Arabidopsis.";
RL Plant Physiol. 131:1191-1208(2003).
RN [5]
RP SUBCELLULAR LOCATION, AND TISSUE SPECIFICITY.
RX PubMed=18239134; DOI=10.1105/tpc.107.052001;
RA Chow C.M., Neto H., Foucart C., Moore I.;
RT "Rab-A2 and Rab-A3 GTPases define a trans-Golgi endosomal membrane domain
RT in Arabidopsis that contributes substantially to the cell plate.";
RL Plant Cell 20:101-123(2008).
CC -!- FUNCTION: Intracellular vesicle trafficking and protein transport.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Endosome membrane {ECO:0000269|PubMed:18239134}.
CC Golgi apparatus, trans-Golgi network membrane
CC {ECO:0000305|PubMed:18239134}; Lipid-anchor
CC {ECO:0000305|PubMed:18239134}. Note=During cytokinesis located to the
CC growing margins of the cell plate.
CC -!- TISSUE SPECIFICITY: Expressed in root tips.
CC {ECO:0000269|PubMed:18239134}.
CC -!- SIMILARITY: Belongs to the small GTPase superfamily. Rab family.
CC {ECO:0000305}.
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DR EMBL; AB016890; BAB09761.1; -; Genomic_DNA.
DR EMBL; CP002688; AED97149.1; -; Genomic_DNA.
DR EMBL; AF370127; AAK43942.1; -; mRNA.
DR EMBL; AY040051; AAK64109.1; -; mRNA.
DR RefSeq; NP_200723.1; NM_125305.5.
DR AlphaFoldDB; Q9FIF9; -.
DR SMR; Q9FIF9; -.
DR STRING; 3702.AT5G59150.1; -.
DR iPTMnet; Q9FIF9; -.
DR PaxDb; Q9FIF9; -.
DR PRIDE; Q9FIF9; -.
DR ProteomicsDB; 236622; -.
DR EnsemblPlants; AT5G59150.1; AT5G59150.1; AT5G59150.
DR GeneID; 836033; -.
DR Gramene; AT5G59150.1; AT5G59150.1; AT5G59150.
DR KEGG; ath:AT5G59150; -.
DR Araport; AT5G59150; -.
DR TAIR; locus:2168469; AT5G59150.
DR eggNOG; KOG0087; Eukaryota.
DR HOGENOM; CLU_041217_23_0_1; -.
DR InParanoid; Q9FIF9; -.
DR OMA; MDHEYDY; -.
DR OrthoDB; 1133775at2759; -.
DR PhylomeDB; Q9FIF9; -.
DR PRO; PR:Q9FIF9; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FIF9; baseline and differential.
DR Genevisible; Q9FIF9; AT.
DR GO; GO:0009504; C:cell plate; IDA:TAIR.
DR GO; GO:0005768; C:endosome; IDA:TAIR.
DR GO; GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central.
DR GO; GO:0009536; C:plastid; HDA:TAIR.
DR GO; GO:0005525; F:GTP binding; IBA:GO_Central.
DR GO; GO:0003924; F:GTPase activity; IBA:GO_Central.
DR GO; GO:0042546; P:cell wall biogenesis; IMP:TAIR.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR001806; Small_GTPase.
DR Pfam; PF00071; Ras; 1.
DR SMART; SM00174; RHO; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR TIGRFAMs; TIGR00231; small_GTP; 1.
DR PROSITE; PS51419; RAB; 1.
PE 2: Evidence at transcript level;
KW Endosome; Golgi apparatus; GTP-binding; Lipoprotein; Membrane;
KW Nucleotide-binding; Prenylation; Protein transport; Reference proteome;
KW Transport.
FT CHAIN 1..217
FT /note="Ras-related protein RABA2d"
FT /id="PRO_0000407342"
FT REGION 196..217
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 41..49
FT /note="Effector region"
FT /evidence="ECO:0000250"
FT BINDING 19..26
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000250"
FT BINDING 67..71
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000250"
FT BINDING 125..128
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000250"
FT BINDING 155..156
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000250"
FT LIPID 214
FT /note="S-geranylgeranyl cysteine"
FT /evidence="ECO:0000250"
FT LIPID 215
FT /note="S-geranylgeranyl cysteine"
FT /evidence="ECO:0000250"
SQ SEQUENCE 217 AA; 23816 MW; 35FDA6DA6609C2FB CRC64;
MAHRVEQDYD YLFKIVLIGD SGVGKTNILS RFTRNEFCLE SKSTIGVEFA TRTLQVEGKT
VKAQIWDTAG QERYRAITSA YYRGAVGALL VYDITKRQTF DNVLRWLREL RDHADSNIVI
MMAGNKADLN HLRSVAEEDG QTLAETEGLS FLETSALEAT NVEKAFQTVL AEIYHIISKK
ALAAQEAAAA NSAIPGQGTT INVEDTSGAG KRGCCST
