RAA6B_ARATH
ID RAA6B_ARATH Reviewed; 229 AA.
AC Q0WQN4; Q9LM28; Q9LMR7;
DT 03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 03-MAY-2011, sequence version 2.
DT 03-AUG-2022, entry version 99.
DE RecName: Full=Ras-related protein RABA6b;
DE Short=AtRABA6b;
GN Name=RABA6B; OrderedLocusNames=At1g18200; ORFNames=T10F20.21;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=12644670; DOI=10.1104/pp.013052;
RA Vernoud V., Horton A.C., Yang Z., Nielsen E.;
RT "Analysis of the small GTPase gene superfamily of Arabidopsis.";
RL Plant Physiol. 131:1191-1208(2003).
CC -!- FUNCTION: Intracellular vesicle trafficking and protein transport.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor
CC {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the small GTPase superfamily. Rab family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF78385.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=AAF97836.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC034107; AAF97836.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AC069551; AAF78385.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE29686.1; -; Genomic_DNA.
DR EMBL; AK228658; BAF00565.1; -; mRNA.
DR RefSeq; NP_173258.2; NM_101680.3.
DR AlphaFoldDB; Q0WQN4; -.
DR SMR; Q0WQN4; -.
DR BioGRID; 23638; 1.
DR STRING; 3702.AT1G18200.1; -.
DR iPTMnet; Q0WQN4; -.
DR PaxDb; Q0WQN4; -.
DR PRIDE; Q0WQN4; -.
DR ProteomicsDB; 236485; -.
DR EnsemblPlants; AT1G18200.1; AT1G18200.1; AT1G18200.
DR GeneID; 838399; -.
DR Gramene; AT1G18200.1; AT1G18200.1; AT1G18200.
DR KEGG; ath:AT1G18200; -.
DR Araport; AT1G18200; -.
DR TAIR; locus:2194095; AT1G18200.
DR eggNOG; KOG0087; Eukaryota.
DR HOGENOM; CLU_041217_23_2_1; -.
DR InParanoid; Q0WQN4; -.
DR OMA; LEIINMM; -.
DR OrthoDB; 1133775at2759; -.
DR PRO; PR:Q0WQN4; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q0WQN4; baseline and differential.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IBA:GO_Central.
DR GO; GO:0006886; P:intracellular protein transport; IBA:GO_Central.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR001806; Small_GTPase.
DR Pfam; PF00071; Ras; 1.
DR SMART; SM00174; RHO; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR TIGRFAMs; TIGR00231; small_GTP; 1.
DR PROSITE; PS51419; RAB; 1.
PE 2: Evidence at transcript level;
KW Cell membrane; GTP-binding; Lipoprotein; Membrane; Nucleotide-binding;
KW Prenylation; Protein transport; Reference proteome; Transport.
FT CHAIN 1..229
FT /note="Ras-related protein RABA6b"
FT /id="PRO_0000407353"
FT MOTIF 42..50
FT /note="Effector region"
FT /evidence="ECO:0000250"
FT BINDING 20..27
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000250"
FT BINDING 68..72
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000250"
FT BINDING 126..129
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000250"
FT BINDING 156..157
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000250"
FT LIPID 226
FT /note="S-geranylgeranyl cysteine"
FT /evidence="ECO:0000250"
FT LIPID 227
FT /note="S-geranylgeranyl cysteine"
FT /evidence="ECO:0000250"
FT CONFLICT 220
FT /note="S -> G (in Ref. 3; BAF00565)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 229 AA; 25617 MW; D7206E26072907B4 CRC64;
MAEESYDEEC DYLFKAVLIG DSAVGKSNLL SRFSRDEFRL DSKPTIGVDF AYRNVRVGDK
TIKAQIWDTA GQERFRAITS SYYRGALGAL LIYDITRRIT FKNIEKWLSE LRGFSSPETV
VVLVGNKSDL GQSREVEEEE GKTLAESEGL YFLETSALEN QNVEEAFLSM IGRIHEVLTQ
KIVLDNRLNG DGNNESNGAV VPPGKEIVNI HEVTATRPLS TSLSNCCYK
