ID   RAB19_XENLA             Reviewed;         213 AA.
AC   Q32NQ0;
DT   24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT   06-DEC-2005, sequence version 1.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=Ras-related protein Rab-19;
GN   Name=rab19;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor
CC       {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the small GTPase superfamily. Rab family.
CC       {ECO:0000305}.
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DR   EMBL; BC108532; AAI08533.1; -; mRNA.
DR   RefSeq; NP_001090134.1; NM_001096665.1.
DR   RefSeq; XP_018106767.1; XM_018251278.1.
DR   RefSeq; XP_018106768.1; XM_018251279.1.
DR   RefSeq; XP_018106769.1; XM_018251280.1.
DR   AlphaFoldDB; Q32NQ0; -.
DR   SMR; Q32NQ0; -.
DR   DNASU; 735212; -.
DR   GeneID; 735212; -.
DR   KEGG; xla:735212; -.
DR   CTD; 735212; -.
DR   Xenbase; XB-GENE-6254087; rab19.L.
DR   OMA; CVVQHFR; -.
DR   OrthoDB; 1149105at2759; -.
DR   Proteomes; UP000186698; Chromosome 3L.
DR   Bgee; 735212; Expressed in internal ear and 14 other tissues.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005225; Small_GTP-bd_dom.
DR   InterPro; IPR001806; Small_GTPase.
DR   Pfam; PF00071; Ras; 1.
DR   SMART; SM00174; RHO; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00231; small_GTP; 1.
DR   PROSITE; PS51419; RAB; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane; GTP-binding; Lipoprotein; Membrane; Methylation;
KW   Nucleotide-binding; Prenylation; Reference proteome.
FT   CHAIN           1..213
FT                   /note="Ras-related protein Rab-19"
FT                   /id="PRO_0000366947"
FT   MOTIF           44..52
FT                   /note="Effector region"
FT                   /evidence="ECO:0000250"
FT   BINDING         22..29
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250"
FT   BINDING         70..74
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250"
FT   BINDING         128..131
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250"
FT   MOD_RES         213
FT                   /note="Cysteine methyl ester"
FT                   /evidence="ECO:0000250"
FT   LIPID           211
FT                   /note="S-geranylgeranyl cysteine"
FT                   /evidence="ECO:0000250"
FT   LIPID           213
FT                   /note="S-geranylgeranyl cysteine"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   213 AA;  24074 MW;  AD167AE1A2077FDD CRC64;
     MPGRGSLEDD PFDFLFKIIL IGDSNVGKTC VVHRFQSGIF MDNQQNTIGV DFTVRSLNIN
     GKKVKVQVWD TAGQERFRTI TQSYYRSAHG AIIAYDITRR QSFESVPHWI YEAGKYGAAN
     LMLMLMGNKS DLAEKRQILF EEACTLAEKH GLLAVLETSA KESHNVDEVF LLMAKELIAR
     NTFHYHNESP RNSFILDSKP VLAPPEPDKS CLC