ID   RAB7_GOSHI              Reviewed;         207 AA.
AC   Q9XER8;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1999, sequence version 1.
DT   03-AUG-2022, entry version 102.
DE   RecName: Full=Ras-related protein Rab7;
GN   Name=RAB7;
OS   Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX   NCBI_TaxID=3635;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=cv. Deltapine 62; TISSUE=Etiolated cotyledon;
RA   Jenkins W.B., Turley R.B., Steele M.;
RT   "A cDNA clone encoding a Rab7 protein from upland cotton (Gossypium
RT   hirsutum L.).";
RL   (er) Plant Gene Register PGR99-064(1999).
CC   -!- FUNCTION: Protein transport. Probably involved in vesicular traffic (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor
CC       {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the small GTPase superfamily. Rab family.
CC       {ECO:0000305}.
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DR   EMBL; AF116243; AAD22451.1; -; mRNA.
DR   RefSeq; NP_001314021.1; NM_001327092.1.
DR   RefSeq; XP_016678040.1; XM_016822551.1.
DR   AlphaFoldDB; Q9XER8; -.
DR   SMR; Q9XER8; -.
DR   PRIDE; Q9XER8; -.
DR   GeneID; 107897195; -.
DR   GeneID; 107913905; -.
DR   KEGG; ghi:107897195; -.
DR   KEGG; ghi:107913905; -.
DR   Proteomes; UP000189702; Chromosome 16.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005774; C:vacuolar membrane; IBA:GO_Central.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005225; Small_GTP-bd_dom.
DR   InterPro; IPR001806; Small_GTPase.
DR   Pfam; PF00071; Ras; 1.
DR   SMART; SM00174; RHO; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00231; small_GTP; 1.
DR   PROSITE; PS51419; RAB; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane; GTP-binding; Lipoprotein; Membrane; Methylation;
KW   Nucleotide-binding; Prenylation; Protein transport; Reference proteome;
KW   Transport.
FT   CHAIN           1..207
FT                   /note="Ras-related protein Rab7"
FT                   /id="PRO_0000121281"
FT   BINDING         15..22
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250"
FT   BINDING         63..67
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250"
FT   BINDING         125..128
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250"
FT   MOD_RES         207
FT                   /note="Cysteine methyl ester"
FT                   /evidence="ECO:0000250"
FT   LIPID           205
FT                   /note="S-geranylgeranyl cysteine"
FT                   /evidence="ECO:0000250"
FT   LIPID           207
FT                   /note="S-geranylgeranyl cysteine"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   207 AA;  23171 MW;  2453D5D3B0DCC617 CRC64;
     MASRRRMLLK VIILGDSGVG KTSLMNQYVN RKFSNQYKAT IGADFLTKEV QFDDRLFTLQ
     IWDTAGQERF QSLGVAFYRG ADCCVLVHDV NVMKSFDNLN NWREEFLIQA SPSDPENFPF
     VVLGNKVDVD GGNSRVVSEK KAKAWCASKG NIPYFETSAK EGFNVDAAFE CIARNALKNE
     PEEEIYLPET IDVASGGRPQ RSTGCEC