RAB7_PRUAR
ID RAB7_PRUAR Reviewed; 207 AA.
AC O24461;
DT 15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 03-AUG-2022, entry version 99.
DE RecName: Full=Ras-related protein Rab7;
OS Prunus armeniaca (Apricot) (Armeniaca vulgaris).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Rosaceae; Amygdaloideae; Amygdaleae; Prunus.
OX NCBI_TaxID=36596;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Bergeron; TISSUE=Fruit;
RA Mbeguie-A-Mbeguie D., Gomez R.-M., Fils-Lycaon B.R.;
RT "Molecular cloning and nucleotide sequence of a Rab7 small GTP-binding
RT protein from apricot fruit. Gene expression during fruit ripening.";
RL (er) Plant Gene Register PGR97-117(1997).
CC -!- FUNCTION: Protein transport. Probably involved in vesicular traffic (By
CC similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor
CC {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the small GTPase superfamily. Rab family.
CC {ECO:0000305}.
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DR EMBL; U82219; AAB71504.1; -; mRNA.
DR AlphaFoldDB; O24461; -.
DR SMR; O24461; -.
DR PRIDE; O24461; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR001806; Small_GTPase.
DR Pfam; PF00071; Ras; 1.
DR SMART; SM00174; RHO; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR TIGRFAMs; TIGR00231; small_GTP; 1.
DR PROSITE; PS51419; RAB; 1.
PE 2: Evidence at transcript level;
KW Cell membrane; GTP-binding; Lipoprotein; Membrane; Methylation;
KW Nucleotide-binding; Prenylation; Protein transport; Transport.
FT CHAIN 1..207
FT /note="Ras-related protein Rab7"
FT /id="PRO_0000121285"
FT BINDING 15..22
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000250"
FT BINDING 63..67
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000250"
FT BINDING 125..128
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000250"
FT MOD_RES 207
FT /note="Cysteine methyl ester"
FT /evidence="ECO:0000250"
FT LIPID 205
FT /note="S-geranylgeranyl cysteine"
FT /evidence="ECO:0000250"
FT LIPID 207
FT /note="S-geranylgeranyl cysteine"
FT /evidence="ECO:0000250"
SQ SEQUENCE 207 AA; 23227 MW; 6B37AEDC67946ECF CRC64;
MASRRRMLLK VIILGDSGVG KTSLMNQYVN RKFSNQYKAT IGADFLTKEV QFEDRLFTLQ
IWDTAGQERF QSLGVAFYRG ADCCVLVYDV NVMKSFENLN NWREEFLIQA TPSDPENFPF
VVLGNKIDVD GGNSRVVSEK KAKAWCASKG NIPYFETSAK EGFNVDDAFQ CIAKNALNNE
PEEEIYLPDT IDVAGGGRQQ RSSGCEC