RABEK_DANRE
ID RABEK_DANRE Reviewed; 351 AA.
AC Q6GQN7;
DT 20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT 19-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 104.
DE RecName: Full=Rab9 effector protein with kelch motifs;
GN Name=rabepk; ORFNames=zgc:91813;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Rab9 effector required for endosome to trans-Golgi network
CC (TGN) transport. {ECO:0000250}.
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DR EMBL; BC072705; AAH72705.1; -; mRNA.
DR RefSeq; NP_001002209.1; NM_001002209.1.
DR RefSeq; XP_005171783.1; XM_005171726.3.
DR AlphaFoldDB; Q6GQN7; -.
DR SMR; Q6GQN7; -.
DR STRING; 7955.ENSDARP00000058270; -.
DR PaxDb; Q6GQN7; -.
DR PRIDE; Q6GQN7; -.
DR Ensembl; ENSDART00000183882; ENSDARP00000148548; ENSDARG00000112165.
DR GeneID; 431756; -.
DR KEGG; dre:431756; -.
DR CTD; 10244; -.
DR ZFIN; ZDB-GENE-040704-52; rabepk.
DR eggNOG; KOG0379; Eukaryota.
DR GeneTree; ENSGT00940000158763; -.
DR HOGENOM; CLU_045313_0_0_1; -.
DR InParanoid; Q6GQN7; -.
DR OMA; HEWDIPE; -.
DR OrthoDB; 933937at2759; -.
DR PhylomeDB; Q6GQN7; -.
DR TreeFam; TF329153; -.
DR Reactome; R-DRE-6811440; Retrograde transport at the Trans-Golgi-Network.
DR PRO; PR:Q6GQN7; -.
DR Proteomes; UP000000437; Genome assembly.
DR Proteomes; UP000814640; Chromosome 5.
DR Bgee; ENSDARG00000112165; Expressed in testis and 23 other tissues.
DR ExpressionAtlas; Q6GQN7; baseline.
DR Gene3D; 2.120.10.80; -; 2.
DR InterPro; IPR011043; Gal_Oxase/kelch_b-propeller.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR011498; Kelch_2.
DR Pfam; PF07646; Kelch_2; 1.
DR SUPFAM; SSF50965; SSF50965; 1.
PE 2: Evidence at transcript level;
KW Kelch repeat; Reference proteome; Repeat.
FT CHAIN 1..351
FT /note="Rab9 effector protein with kelch motifs"
FT /id="PRO_0000280620"
FT REPEAT 54..102
FT /note="Kelch 1"
FT REPEAT 105..156
FT /note="Kelch 2"
FT REPEAT 162..210
FT /note="Kelch 3"
FT REPEAT 214..263
FT /note="Kelch 4"
FT REPEAT 264..313
FT /note="Kelch 5"
FT REPEAT 328..351
FT /note="Kelch 6"
SQ SEQUENCE 351 AA; 38347 MW; 732D5A761C868228 CRC64;
MELIPVLEPE QKPQNRHWYV LEPTGAAPGV SVGHTCSFLP AAHHHDEDGG GKGKIVIVGG
ANPSGSFADS YIINLDTHQW DLPDWEGLQA RYEHCSFTPE SEPQSLWVFG GAEKSTNRNC
VQALRFSDGG EGRRFWQSVQ VTGVPPSGRT YHTNSACVGN RLFVFSGGEA GSSAVTDAQL
HVFDAVSVTW TQPDTTGTPP AQRHGHVITA VGSDIYIHGG MSGEKFHSDM FTLNTESLKW
QKVKAKGDLP PGVAAHSSVT FNKNIFIFGG MTADGATNSM FKFQCDKQRW TLLKFEGDLP
PGRLDHSMCL LPWRVKMEDS EHADVQHLCF VFGGMDTQGV IFNDCLVTVL T