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RABEK_DANRE
ID   RABEK_DANRE             Reviewed;         351 AA.
AC   Q6GQN7;
DT   20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 104.
DE   RecName: Full=Rab9 effector protein with kelch motifs;
GN   Name=rabepk; ORFNames=zgc:91813;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Rab9 effector required for endosome to trans-Golgi network
CC       (TGN) transport. {ECO:0000250}.
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DR   EMBL; BC072705; AAH72705.1; -; mRNA.
DR   RefSeq; NP_001002209.1; NM_001002209.1.
DR   RefSeq; XP_005171783.1; XM_005171726.3.
DR   AlphaFoldDB; Q6GQN7; -.
DR   SMR; Q6GQN7; -.
DR   STRING; 7955.ENSDARP00000058270; -.
DR   PaxDb; Q6GQN7; -.
DR   PRIDE; Q6GQN7; -.
DR   Ensembl; ENSDART00000183882; ENSDARP00000148548; ENSDARG00000112165.
DR   GeneID; 431756; -.
DR   KEGG; dre:431756; -.
DR   CTD; 10244; -.
DR   ZFIN; ZDB-GENE-040704-52; rabepk.
DR   eggNOG; KOG0379; Eukaryota.
DR   GeneTree; ENSGT00940000158763; -.
DR   HOGENOM; CLU_045313_0_0_1; -.
DR   InParanoid; Q6GQN7; -.
DR   OMA; HEWDIPE; -.
DR   OrthoDB; 933937at2759; -.
DR   PhylomeDB; Q6GQN7; -.
DR   TreeFam; TF329153; -.
DR   Reactome; R-DRE-6811440; Retrograde transport at the Trans-Golgi-Network.
DR   PRO; PR:Q6GQN7; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 5.
DR   Bgee; ENSDARG00000112165; Expressed in testis and 23 other tissues.
DR   ExpressionAtlas; Q6GQN7; baseline.
DR   Gene3D; 2.120.10.80; -; 2.
DR   InterPro; IPR011043; Gal_Oxase/kelch_b-propeller.
DR   InterPro; IPR015915; Kelch-typ_b-propeller.
DR   InterPro; IPR011498; Kelch_2.
DR   Pfam; PF07646; Kelch_2; 1.
DR   SUPFAM; SSF50965; SSF50965; 1.
PE   2: Evidence at transcript level;
KW   Kelch repeat; Reference proteome; Repeat.
FT   CHAIN           1..351
FT                   /note="Rab9 effector protein with kelch motifs"
FT                   /id="PRO_0000280620"
FT   REPEAT          54..102
FT                   /note="Kelch 1"
FT   REPEAT          105..156
FT                   /note="Kelch 2"
FT   REPEAT          162..210
FT                   /note="Kelch 3"
FT   REPEAT          214..263
FT                   /note="Kelch 4"
FT   REPEAT          264..313
FT                   /note="Kelch 5"
FT   REPEAT          328..351
FT                   /note="Kelch 6"
SQ   SEQUENCE   351 AA;  38347 MW;  732D5A761C868228 CRC64;
     MELIPVLEPE QKPQNRHWYV LEPTGAAPGV SVGHTCSFLP AAHHHDEDGG GKGKIVIVGG
     ANPSGSFADS YIINLDTHQW DLPDWEGLQA RYEHCSFTPE SEPQSLWVFG GAEKSTNRNC
     VQALRFSDGG EGRRFWQSVQ VTGVPPSGRT YHTNSACVGN RLFVFSGGEA GSSAVTDAQL
     HVFDAVSVTW TQPDTTGTPP AQRHGHVITA VGSDIYIHGG MSGEKFHSDM FTLNTESLKW
     QKVKAKGDLP PGVAAHSSVT FNKNIFIFGG MTADGATNSM FKFQCDKQRW TLLKFEGDLP
     PGRLDHSMCL LPWRVKMEDS EHADVQHLCF VFGGMDTQGV IFNDCLVTVL T
 
 
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