ID   RACA_BACLD              Reviewed;         186 AA.
AC   Q65DU9; Q62PC1;
DT   21-FEB-2006, integrated into UniProtKB/Swiss-Prot.
DT   25-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 102.
DE   RecName: Full=Chromosome-anchoring protein RacA {ECO:0000255|HAMAP-Rule:MF_01170};
GN   Name=racA {ECO:0000255|HAMAP-Rule:MF_01170};
GN   OrderedLocusNames=BLi03951, BL04032;
OS   Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 /
OS   NBRC 12200 / NCIMB 9375 / NCTC 10341 / NRRL NRS-1264 / Gibson 46).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=279010;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 / NBRC 12200 / NCIMB 9375
RC   / NCTC 10341 / NRRL NRS-1264 / Gibson 46;
RX   PubMed=15383718; DOI=10.1159/000079829;
RA   Veith B., Herzberg C., Steckel S., Feesche J., Maurer K.H., Ehrenreich P.,
RA   Baeumer S., Henne A., Liesegang H., Merkl R., Ehrenreich A., Gottschalk G.;
RT   "The complete genome sequence of Bacillus licheniformis DSM13, an organism
RT   with great industrial potential.";
RL   J. Mol. Microbiol. Biotechnol. 7:204-211(2004).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 / NBRC 12200 / NCIMB 9375
RC   / NCTC 10341 / NRRL NRS-1264 / Gibson 46;
RX   PubMed=15461803; DOI=10.1186/gb-2004-5-10-r77;
RA   Rey M.W., Ramaiya P., Nelson B.A., Brody-Karpin S.D., Zaretsky E.J.,
RA   Tang M., Lopez de Leon A., Xiang H., Gusti V., Clausen I.G., Olsen P.B.,
RA   Rasmussen M.D., Andersen J.T., Joergensen P.L., Larsen T.S., Sorokin A.,
RA   Bolotin A., Lapidus A., Galleron N., Ehrlich S.D., Berka R.M.;
RT   "Complete genome sequence of the industrial bacterium Bacillus
RT   licheniformis and comparisons with closely related Bacillus species.";
RL   Genome Biol. 5:R77.1-R77.12(2004).
CC   -!- FUNCTION: Required for the formation of axial filaments and for
CC       anchoring the origin regions at the cell poles in sporulating cells,
CC       thus ensuring proper chromosome segregation in the prespore. Binds in a
CC       dispersed manner throughout the chromosome but preferentially to sites
CC       clustered in the origin portion of the chromosome, causing condensation
CC       of the chromosome and its remodeling into an elongated, anchored
CC       structure. {ECO:0000255|HAMAP-Rule:MF_01170}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01170}.
CC       Note=Localizes to cell poles and nucleoid. {ECO:0000255|HAMAP-
CC       Rule:MF_01170}.
CC   -!- SIMILARITY: Belongs to the RacA family. {ECO:0000255|HAMAP-
CC       Rule:MF_01170}.
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DR   EMBL; CP000002; AAU25390.1; -; Genomic_DNA.
DR   EMBL; AE017333; AAU42765.1; -; Genomic_DNA.
DR   RefSeq; WP_011198392.1; NC_006322.1.
DR   AlphaFoldDB; Q65DU9; -.
DR   SMR; Q65DU9; -.
DR   STRING; 279010.BL04032; -.
DR   EnsemblBacteria; AAU25390; AAU25390; BL04032.
DR   KEGG; bld:BLi03951; -.
DR   KEGG; bli:BL04032; -.
DR   PATRIC; fig|279010.13.peg.4020; -.
DR   eggNOG; COG0789; Bacteria.
DR   HOGENOM; CLU_111022_0_0_9; -.
DR   OMA; WVKQLNL; -.
DR   OrthoDB; 1287443at2; -.
DR   BioCyc; BLIC279010:BLI_RS19420-MON; -.
DR   Proteomes; UP000000606; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003690; F:double-stranded DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0008356; P:asymmetric cell division; IEA:UniProtKB-UniRule.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-UniRule.
DR   GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01170; RacA; 1.
DR   InterPro; IPR023522; Chrosome_anchoring_RacA.
DR   InterPro; IPR009061; DNA-bd_dom_put_sf.
DR   InterPro; IPR000551; MerR-type_HTH_dom.
DR   Pfam; PF13411; MerR_1; 1.
DR   SUPFAM; SSF46955; SSF46955; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Chromosome partition; Coiled coil; Cytoplasm;
KW   DNA-binding; Reference proteome; Sporulation.
FT   CHAIN           1..186
FT                   /note="Chromosome-anchoring protein RacA"
FT                   /id="PRO_0000224156"
FT   DNA_BIND        3..23
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01170"
FT   REGION          158..186
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          90..170
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01170"
FT   COMPBIAS        158..180
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   186 AA;  22260 MW;  ACC8B9212F2F12D8 CRC64;
     MNTADAANEL GVSTKTVQRW VKQLQLPASR NELGHYFFTE DDIAILKEVK EQLKNGTPMQ
     DVTVKRPKKT FFIKKNEMIQ TKEPALQLNE RLEERLQRFL EHEQLERELL QKKIAELERK
     LEQKADEVVS YQLLQQRREL EEERQQIKHL EQKISQLESM NRREKDTAVR REEKKPKSKL
     KSIFSF