ID   RACB_ENTHI              Reviewed;         163 AA.
AC   Q24815;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   03-AUG-2022, entry version 94.
DE   RecName: Full=Rho-related protein racB;
DE   Flags: Fragment;
GN   Name=RACB;
OS   Entamoeba histolytica.
OC   Eukaryota; Amoebozoa; Evosea; Archamoebae; Mastigamoebida; Entamoebidae;
OC   Entamoeba.
OX   NCBI_TaxID=5759;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 30459 / HM-1:IMSS;
RX   PubMed=8964500; DOI=10.1016/0378-1119(96)00232-6;
RA   Lohia A., Samuelson J.;
RT   "Heterogeneity of Entamoeba histolytica rac genes encoding p21rac
RT   homologues.";
RL   Gene 173:205-208(1996).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor
CC       {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the small GTPase superfamily. Rho family.
CC       {ECO:0000305}.
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DR   EMBL; U29721; AAC47297.1; -; Genomic_DNA.
DR   PIR; PC4200; PC4200.
DR   AlphaFoldDB; Q24815; -.
DR   SMR; Q24815; -.
DR   STRING; 5759.rna_EHI_140190-1; -.
DR   VEuPathDB; AmoebaDB:EHI5A_045250; -.
DR   VEuPathDB; AmoebaDB:EHI7A_023430; -.
DR   VEuPathDB; AmoebaDB:EHI8A_021070; -.
DR   VEuPathDB; AmoebaDB:EHI_140190; -.
DR   VEuPathDB; AmoebaDB:KM1_052920; -.
DR   eggNOG; KOG0393; Eukaryota.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005225; Small_GTP-bd_dom.
DR   InterPro; IPR001806; Small_GTPase.
DR   InterPro; IPR003578; Small_GTPase_Rho.
DR   PANTHER; PTHR24072; PTHR24072; 1.
DR   Pfam; PF00071; Ras; 1.
DR   SMART; SM00174; RHO; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00231; small_GTP; 1.
DR   PROSITE; PS51420; RHO; 1.
PE   3: Inferred from homology;
KW   Cell membrane; GTP-binding; Lipoprotein; Membrane; Nucleotide-binding;
KW   Prenylation.
FT   CHAIN           <1..>163
FT                   /note="Rho-related protein racB"
FT                   /id="PRO_0000198911"
FT   MOTIF           23..31
FT                   /note="Effector region"
FT                   /evidence="ECO:0000255"
FT   BINDING         1..8
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250"
FT   BINDING         48..52
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250"
FT   BINDING         106..109
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250"
FT   NON_TER         1
FT   NON_TER         163
SQ   SEQUENCE   163 AA;  18121 MW;  F4647E520FF8E8FD CRC64;
     GAGGVGKTCL LVSYTTNAFP TEYVPTVFDN YSATVMVDSR PINLGLWDTA GQEDYDRIRP
     LSYPQTDVFL LCFSVVSPPS FENISSKWKP EVSHHCPNAP CLLIGTKIDI RDEQTQTNKT
     CDKKIEPITS EQGEAKCKDI GALKYIECSA LTQKNLRYVF DEA