RAD14_CANAL
ID RAD14_CANAL Reviewed; 396 AA.
AC P53709; A0A1D8PR04; Q3MPE1; Q5AH21;
DT 01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT 05-MAY-2009, sequence version 2.
DT 25-MAY-2022, entry version 112.
DE RecName: Full=DNA repair protein RAD14;
GN Name=RAD14; OrderedLocusNames=CAALFM_C702020WA;
GN ORFNames=CaJ7.0232, CaO19.13870, CaO19.6517;
OS Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=237561;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC5314 / ATCC MYA-2876;
RX PubMed=15937140; DOI=10.1534/genetics.104.034652;
RA Chibana H., Oka N., Nakayama H., Aoyama T., Magee B.B., Magee P.T.,
RA Mikami Y.;
RT "Sequence finishing and gene mapping for Candida albicans chromosome 7 and
RT syntenic analysis against the Saccharomyces cerevisiae genome.";
RL Genetics 170:1525-1537(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC5314 / ATCC MYA-2876;
RX PubMed=15123810; DOI=10.1073/pnas.0401648101;
RA Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B.,
RA Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W.,
RA Scherer S.;
RT "The diploid genome sequence of Candida albicans.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=SC5314 / ATCC MYA-2876;
RX PubMed=17419877; DOI=10.1186/gb-2007-8-4-r52;
RA van het Hoog M., Rast T.J., Martchenko M., Grindle S., Dignard D.,
RA Hogues H., Cuomo C., Berriman M., Scherer S., Magee B.B., Whiteway M.,
RA Chibana H., Nantel A., Magee P.T.;
RT "Assembly of the Candida albicans genome into sixteen supercontigs aligned
RT on the eight chromosomes.";
RL Genome Biol. 8:RESEARCH52.1-RESEARCH52.12(2007).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC STRAIN=SC5314 / ATCC MYA-2876;
RX PubMed=24025428; DOI=10.1186/gb-2013-14-9-r97;
RA Muzzey D., Schwartz K., Weissman J.S., Sherlock G.;
RT "Assembly of a phased diploid Candida albicans genome facilitates allele-
RT specific measurements and provides a simple model for repeat and indel
RT structure.";
RL Genome Biol. 14:RESEARCH97.1-RESEARCH97.14(2013).
RN [5]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 276-396.
RC STRAIN=ATCC 10261 / CBS 2718 / NBRC 1061;
RX PubMed=7591093; DOI=10.1128/iai.63.11.4506-4514.1995;
RA Swoboda R.K., Bertram G., Budge S., Gooday G.W., Gow N.A.R., Brown A.J.P.;
RT "Structure and regulation of the HSP90 gene from the pathogenic fungus
RT Candida albicans.";
RL Infect. Immun. 63:4506-4514(1995).
CC -!- FUNCTION: Involved in DNA excision repair. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus.
CC -!- SIMILARITY: Belongs to the XPA family. {ECO:0000305}.
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DR EMBL; AP006852; BAE44719.1; -; Genomic_DNA.
DR EMBL; CP017629; AOW30565.1; -; Genomic_DNA.
DR EMBL; X81025; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_721355.1; XM_716262.1.
DR AlphaFoldDB; P53709; -.
DR SMR; P53709; -.
DR STRING; 237561.P53709; -.
DR GeneID; 3636953; -.
DR KEGG; cal:CAALFM_C702020WA; -.
DR CGD; CAL0000195624; RAD14.
DR VEuPathDB; FungiDB:C7_02020W_A; -.
DR eggNOG; KOG4017; Eukaryota.
DR HOGENOM; CLU_053731_0_1_1; -.
DR InParanoid; P53709; -.
DR OMA; MMLFLRF; -.
DR OrthoDB; 1542306at2759; -.
DR Proteomes; UP000000559; Chromosome 7.
DR GO; GO:0000110; C:nucleotide-excision repair factor 1 complex; IBA:GO_Central.
DR GO; GO:0003684; F:damaged DNA binding; IBA:GO_Central.
DR GO; GO:0008270; F:zinc ion binding; IEA:EnsemblFungi.
DR GO; GO:0006284; P:base-excision repair; IBA:GO_Central.
DR GO; GO:1901255; P:nucleotide-excision repair involved in interstrand cross-link repair; IBA:GO_Central.
DR GO; GO:0000715; P:nucleotide-excision repair, DNA damage recognition; IBA:GO_Central.
DR GO; GO:0033683; P:nucleotide-excision repair, DNA incision; IBA:GO_Central.
DR GO; GO:0070914; P:UV-damage excision repair; IBA:GO_Central.
DR Gene3D; 3.90.530.10; -; 1.
DR InterPro; IPR009061; DNA-bd_dom_put_sf.
DR InterPro; IPR000465; XPA.
DR InterPro; IPR022656; XPA_C.
DR InterPro; IPR037129; XPA_sf.
DR InterPro; IPR022652; Znf_XPA_CS.
DR PANTHER; PTHR10142; PTHR10142; 1.
DR Pfam; PF05181; XPA_C; 1.
DR Pfam; PF01286; XPA_N; 1.
DR SUPFAM; SSF46955; SSF46955; 1.
DR TIGRFAMs; TIGR00598; rad14; 1.
PE 3: Inferred from homology;
KW DNA damage; DNA repair; DNA-binding; Metal-binding; Nucleus;
KW Reference proteome; Zinc; Zinc-finger.
FT CHAIN 1..396
FT /note="DNA repair protein RAD14"
FT /id="PRO_0000208653"
FT ZN_FING 223..247
FT REGION 20..101
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 116..156
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 20..40
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 41..82
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 84..101
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 129..156
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 396 AA; 46540 MW; EF8EB6492C1DB2D9 CRC64;
MASHIRGNLT EEQLKRIEAN RKRALERLQQ KKKKDAGEHV PSSTPKSTST TTTKETGSYS
PTKTLSQIVN SDSVQVSSKF VEIETDGSVK KRRVLTEEQR QKIEQNRLRA IEIQKNLKQR
ENQKDDSTTS SKPVDNIRLN QNRPDSVVSS TKKFQPPPIR KQDYIEFDFA TMKDTKGGFL
QDEKTNTQGA DEQTLQDWKN KQRELQKIRE LPPPIDLQNI PRCRECQSME VDANLMTNFN
VRACRKCIKA LPEKYSLLTK TECKEDYLLT EPELQDTTLL PRIEKPNPHG YSRMQLFVRF
QVEEFAWKKW GGPEELDKEW ERREENKVKR KEKKYHDQLR EMRKRTRAEE YTRKLRDGKS
LGERHVHDWS SPVNIDKHTI KRRCIDCGIE TEEVVI
