RAD23_ORYSJ
ID RAD23_ORYSJ Reviewed; 392 AA.
AC Q40742; Q0J1W7; Q69MY0;
DT 23-NOV-2004, integrated into UniProtKB/Swiss-Prot.
DT 23-NOV-2004, sequence version 2.
DT 03-AUG-2022, entry version 132.
DE RecName: Full=Probable ubiquitin receptor RAD23;
DE Short=OsRAD23;
DE AltName: Full=Probable DNA repair protein RAD23;
GN Name=RAD23; OrderedLocusNames=Os09g0407200, LOC_Os09g24200;
GN ORFNames=OJ1261_A08.49, OsJ_29306 {ECO:0000312|EMBL:EAZ44680.1},
GN P0465E03.1;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], INTERACTION WITH VP1, AND TISSUE SPECIFICITY.
RC STRAIN=cv. Nipponbare;
RX PubMed=9225866; DOI=10.1023/a:1005870227632;
RA Schultz T.F., Quatrano R.S.;
RT "Characterization and expression of a rice RAD23 gene.";
RL Plant Mol. Biol. 34:557-562(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
CC -!- FUNCTION: May be involved in nucleotide excision repair (By
CC similarity). Binds and presumably selects ubiquitin-conjugates for
CC destruction. Prefers multiubiquitin chains rather than single
CC ubiquitins, with a binding affinity for 'Lys-48'-linked ubiquitin
CC chains. Acts as a ubiquitin receptor that associates with the 26S
CC proteasomal docking subunit RPN10 for the indirect recognition of
CC ubiquitinated substrates of ubiquitin/26S proteasome-mediated
CC proteolysis (UPP) (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Interacts with 'Lys-48'-linked polyubiquitin chains (By
CC similarity). Interacts with RPN10 (By similarity). Interacts with VP1.
CC {ECO:0000250, ECO:0000269|PubMed:9225866}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Mostly expressed in vegetative tissues.
CC {ECO:0000269|PubMed:9225866}.
CC -!- SIMILARITY: Belongs to the RAD23 family. {ECO:0000305}.
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DR EMBL; U63530; AAB65841.1; -; mRNA.
DR EMBL; AP005707; BAD36240.1; -; Genomic_DNA.
DR EMBL; AP005722; BAD36295.1; -; Genomic_DNA.
DR EMBL; AP008215; BAF25048.1; -; Genomic_DNA.
DR EMBL; AP014965; BAT08015.1; -; Genomic_DNA.
DR EMBL; CM000146; EAZ44680.1; -; Genomic_DNA.
DR PIR; T04150; T04150.
DR RefSeq; XP_015611791.1; XM_015756305.1.
DR AlphaFoldDB; Q40742; -.
DR SMR; Q40742; -.
DR STRING; 4530.OS09T0407200-01; -.
DR PaxDb; Q40742; -.
DR PRIDE; Q40742; -.
DR EnsemblPlants; Os09t0407200-01; Os09t0407200-01; Os09g0407200.
DR GeneID; 4347014; -.
DR Gramene; Os09t0407200-01; Os09t0407200-01; Os09g0407200.
DR KEGG; osa:4347014; -.
DR eggNOG; KOG0011; Eukaryota.
DR HOGENOM; CLU_040364_1_0_1; -.
DR InParanoid; Q40742; -.
DR OMA; MGERNEM; -.
DR OrthoDB; 1260050at2759; -.
DR Proteomes; UP000000763; Chromosome 9.
DR Proteomes; UP000007752; Chromosome 9.
DR Proteomes; UP000059680; Chromosome 9.
DR ExpressionAtlas; Q40742; baseline and differential.
DR Genevisible; Q40742; OS.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0005654; C:nucleoplasm; IBA:GO_Central.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0031593; F:polyubiquitin modification-dependent protein binding; IBA:GO_Central.
DR GO; GO:0070628; F:proteasome binding; IBA:GO_Central.
DR GO; GO:0043130; F:ubiquitin binding; IBA:GO_Central.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IBA:GO_Central.
DR Gene3D; 1.10.10.540; -; 1.
DR InterPro; IPR004806; Rad23.
DR InterPro; IPR006636; STI1_HS-bd.
DR InterPro; IPR015940; UBA.
DR InterPro; IPR009060; UBA-like_sf.
DR InterPro; IPR000626; Ubiquitin-like_dom.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR InterPro; IPR015360; XPC-bd.
DR InterPro; IPR036353; XPC-bd_sf.
DR Pfam; PF00627; UBA; 2.
DR Pfam; PF00240; ubiquitin; 1.
DR Pfam; PF09280; XPC-binding; 1.
DR PRINTS; PR01839; RAD23PROTEIN.
DR SMART; SM00727; STI1; 1.
DR SMART; SM00165; UBA; 2.
DR SMART; SM00213; UBQ; 1.
DR SUPFAM; SSF101238; SSF101238; 1.
DR SUPFAM; SSF46934; SSF46934; 2.
DR SUPFAM; SSF54236; SSF54236; 1.
DR TIGRFAMs; TIGR00601; rad23; 1.
DR PROSITE; PS50030; UBA; 2.
DR PROSITE; PS50053; UBIQUITIN_2; 1.
PE 1: Evidence at protein level;
KW DNA damage; DNA repair; Nucleus; Reference proteome; Repeat.
FT CHAIN 1..392
FT /note="Probable ubiquitin receptor RAD23"
FT /id="PRO_0000114912"
FT DOMAIN 1..79
FT /note="Ubiquitin-like"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00214"
FT DOMAIN 156..199
FT /note="UBA 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00212"
FT DOMAIN 260..303
FT /note="STI1"
FT DOMAIN 342..382
FT /note="UBA 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00212"
FT REGION 80..109
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 209..237
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 80..105
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 217..237
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 345
FT /note="N -> D (in Ref. 1; AAB65841)"
FT /evidence="ECO:0000305"
FT CONFLICT 353
FT /note="A -> P (in Ref. 1; AAB65841)"
FT /evidence="ECO:0000305"
FT CONFLICT 387
FT /note="D -> A (in Ref. 1; AAB65841)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 392 AA; 41771 MW; 9317F6374CC0BAD8 CRC64;
MKISVKTLKG STFQIEVDSA QKVADVKRII ETTQGQHIYP AEQQMLIHQG KVLKDDTTLD
ENKVLENSFL VIMLRQGKGS SSSAPATSKA PSNQAPPTQT VPAAPASQAP VAPATTVPVT
VSAPTPTATA SPAPAVAVSS EADNYGQATS NLVAGSNLEA TIQSILEMGG GIWDRDIVLH
ALSAAFNNPE RAVEYLYSGV PEQMDIPVPP PSIQPANPTQ ASQATQPAAP SILSSGPNAS
PLDLFPQALP NASTDAAGLG NLDALRNNAQ FRTLLSLVQA NPQILQPLLQ ELGKQNPQIL
QLIQENQAEF LHLINEPAEG DDEENLLDQF PEAMPQTIAV TPEENEAILR LEAMGFDRAL
VLDVFFACNK DEQLAANYLL DHMNEFDDEG PP
