ID   RAD52_CHICK             Reviewed;         422 AA.
AC   P39022;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   03-AUG-2022, entry version 95.
DE   RecName: Full=DNA repair protein RAD52 homolog;
GN   Name=RAD52;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Testis;
RX   PubMed=8290357; DOI=10.1093/nar/21.25.5945;
RA   Bezzubova O.Y., Schmidt H., Ostermann K., Heyer W.-D., Buerstedde J.-M.;
RT   "Identification of a chicken RAD52 homologue suggests conservation of the
RT   RAD52 recombination pathway throughout the evolution of higher
RT   eukaryotes.";
RL   Nucleic Acids Res. 21:5945-5949(1993).
CC   -!- FUNCTION: Involved in double-stranded break repair. Plays a central
CC       role in genetic recombination and DNA repair by promoting the annealing
CC       of complementary single-stranded DNA and by stimulation of the RAD51
CC       recombinase (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: The full-length protein forms heptameric rings. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the RAD52 family. {ECO:0000305}.
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DR   EMBL; U01047; -; NOT_ANNOTATED_CDS; mRNA.
DR   PIR; S41514; S41514.
DR   AlphaFoldDB; P39022; -.
DR   SMR; P39022; -.
DR   STRING; 9031.ENSGALP00000021180; -.
DR   PaxDb; P39022; -.
DR   VEuPathDB; HostDB:geneid_418152; -.
DR   eggNOG; KOG4141; Eukaryota.
DR   InParanoid; P39022; -.
DR   PhylomeDB; P39022; -.
DR   Proteomes; UP000000539; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000730; P:DNA recombinase assembly; IEA:InterPro.
DR   GO; GO:0045002; P:double-strand break repair via single-strand annealing; IEA:InterPro.
DR   Gene3D; 3.30.390.80; -; 1.
DR   InterPro; IPR004585; DNA_recomb/repair_Rad52.
DR   InterPro; IPR041247; Rad52_fam.
DR   InterPro; IPR007232; Rad52_Rad59_Rad22.
DR   InterPro; IPR042525; Rad52_Rad59_Rad22_sf.
DR   PANTHER; PTHR12132; PTHR12132; 1.
DR   Pfam; PF04098; Rad52_Rad22; 1.
DR   TIGRFAMs; TIGR00607; rad52; 1.
PE   2: Evidence at transcript level;
KW   DNA damage; DNA recombination; DNA repair; DNA-binding; Nucleus;
KW   Reference proteome.
FT   CHAIN           1..422
FT                   /note="DNA repair protein RAD52 homolog"
FT                   /id="PRO_0000173883"
FT   DNA_BIND        153..157
FT                   /evidence="ECO:0000250"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          228..255
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          281..306
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          343..422
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        239..255
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        288..304
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        385..408
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   422 AA;  47722 MW;  CA718D652D7E7A5C CRC64;
     MPERQGKDSE SHVSSSCTST SNSVACFGQY QYTANEYQAI QHALRQKLGP EYISSRQAGG
     GQKVCYIEGH KVISLANEMF GFNGWAHSVT QQNVDFVDLN NGRFYVGVCA FVKVQLKDGS
     YHEDVGYGVS EGLKSKALSL EKARKEAVTD GLKRALKCFG NALGNCILDK DYLQAVNKLP
     RQMPPELDLV KTKRQDYEPE IEKARYDGCL ERQNPGWRQQ CEMAPTCKPT HTEASRVTED
     QKQPSSSGNT DSPAVECDAT YQRKLRQKQL QQQFWEQMEK RRQVKEVTPS SKQATANPPV
     KHSTPAAVQQ ELAIEEEFFA DDLELWDISL ETTDLNKLMC HKAAGSPAAQ QPPETPHRRH
     QMTTRNRTPQ RMHYHKPPVR FAQLQPSAAL TSNSHGANQR TPAEHSPYRR SQSWKKRRLE
     PT