ID   RAD52_MAGO7             Reviewed;         555 AA.
AC   Q8NK72; A4QYI8; G4N668;
DT   27-SEP-2004, integrated into UniProtKB/Swiss-Prot.
DT   25-JAN-2012, sequence version 2.
DT   25-MAY-2022, entry version 88.
DE   RecName: Full=DNA repair and recombination protein rhm52;
DE   AltName: Full=RAD52 homolog;
GN   Name=RHM52; ORFNames=MGG_08585;
OS   Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) (Rice blast
OS   fungus) (Pyricularia oryzae).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Magnaporthales; Pyriculariaceae; Pyricularia.
OX   NCBI_TaxID=242507;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA], INDUCTION, AND FUNCTION.
RC   STRAIN=Ina168;
RX   DOI=10.1007/s10327-005-0238-8;
RA   Elegado E.B., Iwasaki A., Sales M.A., Ishii C., Tomita F., Sone T.;
RT   "Oxidative stress induces high transcription of Rmh52 and Rhm54, novel
RT   genes identified as being involved in recombinational repair in Magnaporthe
RT   grisea.";
RL   J. Gen. Plant Pathol. 72:16-19(2006).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=70-15 / ATCC MYA-4617 / FGSC 8958;
RX   PubMed=15846337; DOI=10.1038/nature03449;
RA   Dean R.A., Talbot N.J., Ebbole D.J., Farman M.L., Mitchell T.K.,
RA   Orbach M.J., Thon M.R., Kulkarni R., Xu J.-R., Pan H., Read N.D.,
RA   Lee Y.-H., Carbone I., Brown D., Oh Y.Y., Donofrio N., Jeong J.S.,
RA   Soanes D.M., Djonovic S., Kolomiets E., Rehmeyer C., Li W., Harding M.,
RA   Kim S., Lebrun M.-H., Bohnert H., Coughlan S., Butler J., Calvo S.E.,
RA   Ma L.-J., Nicol R., Purcell S., Nusbaum C., Galagan J.E., Birren B.W.;
RT   "The genome sequence of the rice blast fungus Magnaporthe grisea.";
RL   Nature 434:980-986(2005).
CC   -!- FUNCTION: Involved in DNA double-strand break (DSB) repair and
CC       recombination. Promotes the annealing of complementary single-stranded
CC       DNA and by stimulation of the RAD51 recombinase (By similarity).
CC       {ECO:0000250, ECO:0000269|Ref.1}.
CC   -!- SUBUNIT: Part of a complex that includes RAD51, RAD52 and RAD59.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- INDUCTION: In response to MMS and UV treatment, and in response to heat
CC       shock and oxidative stress. {ECO:0000269|Ref.1}.
CC   -!- SIMILARITY: Belongs to the RAD52 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AB091332; BAC11860.1; -; Genomic_DNA.
DR   EMBL; CM001234; EHA49792.1; -; Genomic_DNA.
DR   RefSeq; XP_003716111.1; XM_003716063.1.
DR   AlphaFoldDB; Q8NK72; -.
DR   SMR; Q8NK72; -.
DR   STRING; 318829.MGG_08585T0; -.
DR   EnsemblFungi; MGG_08585T0; MGG_08585T0; MGG_08585.
DR   GeneID; 2678699; -.
DR   KEGG; mgr:MGG_08585; -.
DR   VEuPathDB; FungiDB:MGG_08585; -.
DR   eggNOG; KOG4141; Eukaryota.
DR   HOGENOM; CLU_011431_4_0_1; -.
DR   InParanoid; Q8NK72; -.
DR   OMA; QFDPHAE; -.
DR   OrthoDB; 1572665at2759; -.
DR   Proteomes; UP000009058; Chromosome 4.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000730; P:DNA recombinase assembly; IEA:InterPro.
DR   GO; GO:0045002; P:double-strand break repair via single-strand annealing; IEA:InterPro.
DR   Gene3D; 3.30.390.80; -; 1.
DR   InterPro; IPR004585; DNA_recomb/repair_Rad52.
DR   InterPro; IPR041247; Rad52_fam.
DR   InterPro; IPR007232; Rad52_Rad59_Rad22.
DR   InterPro; IPR042525; Rad52_Rad59_Rad22_sf.
DR   PANTHER; PTHR12132; PTHR12132; 1.
DR   Pfam; PF04098; Rad52_Rad22; 1.
DR   TIGRFAMs; TIGR00607; rad52; 1.
PE   2: Evidence at transcript level;
KW   DNA damage; DNA recombination; DNA repair; DNA-binding; Nucleus;
KW   Reference proteome; Stress response.
FT   CHAIN           1..555
FT                   /note="DNA repair and recombination protein rhm52"
FT                   /id="PRO_0000173889"
FT   DNA_BIND        148..152
FT                   /evidence="ECO:0000250"
FT   REGION          197..232
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          251..555
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        260..339
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        356..384
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        436..450
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        465..500
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   555 AA;  59151 MW;  6AF0ED4EA6A66852 CRC64;
     MPAPGDQHSR ISNPFEDVKP RVSEYTAQEI ATLQTRLERQ LGPEYLSARA GPSGQKVHYV
     AAEKVIGLAN EVFGFNGWSS SIQNIQVDFV DEHPQTLKIS LGLHVVVRVT LRDGTFHEDI
     GYGHIENCKG KAMAFEKAKK EGTTDALKRA LRNFGNVLGN CVYDKAYLAK VTKLKVEPTK
     FDELNLHRHA DFAKKDVVAE PRLPPVKPEP SNTASAAPHP PLPPLPEADS FDDLLGEFDE
     ADFCVVDADG HPDEVVLPEN SHASGSSGNT GASTTNRGPG APSGNQSNQQ RPMQPSSRMN
     LNGPAGRPQP QTPNHQINRS GPQNGSINNQ QNNHGMRPSP HMANQGRPPP PPQNNNNTSN
     GTGPHQRPLG NGPQQNTPPP NNGAATAPSG AEPVAFFSAR AVARVPDDAS LPPPPGTATP
     TALFNPKAES PSIRKTPGID HSSSRPVSRT GQHVPAKPVQ DGGGLANDNP SNNAGNGVQN
     QPQKPQPSQQ RGSILNPQFD QSRRIGAPGG AASPLSNRNQ YRPPTMMKRP PLADVPNGTS
     NGNGTPGDSK RMKLN