ID   RAD59_CANGA             Reviewed;         212 AA.
AC   Q6FWE1;
DT   27-SEP-2004, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 86.
DE   RecName: Full=DNA repair protein RAD59;
GN   Name=RAD59; OrderedLocusNames=CAGL0D00902g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Involved in the repair of double-strand breaks in DNA during
CC       vegetative growth via recombination and single-strand annealing.
CC       Anneals complementary single-stranded DNA (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with RAD51 and RAD52. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RAD52 family. {ECO:0000305}.
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DR   EMBL; CR380950; CAG58364.1; -; Genomic_DNA.
DR   RefSeq; XP_445453.1; XM_445453.1.
DR   AlphaFoldDB; Q6FWE1; -.
DR   SMR; Q6FWE1; -.
DR   STRING; 5478.XP_445453.1; -.
DR   EnsemblFungi; CAG58364; CAG58364; CAGL0D00902g.
DR   GeneID; 2887211; -.
DR   KEGG; cgr:CAGL0D00902g; -.
DR   CGD; CAL0128311; CAGL0D00902g.
DR   VEuPathDB; FungiDB:CAGL0D00902g; -.
DR   eggNOG; KOG4141; Eukaryota.
DR   HOGENOM; CLU_091426_0_0_1; -.
DR   InParanoid; Q6FWE1; -.
DR   OMA; WSVQRIG; -.
DR   Proteomes; UP000002428; Chromosome D.
DR   GO; GO:0005759; C:mitochondrial matrix; IEA:EnsemblFungi.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006277; P:DNA amplification; IEA:EnsemblFungi.
DR   GO; GO:0045002; P:double-strand break repair via single-strand annealing; IEA:EnsemblFungi.
DR   GO; GO:0043504; P:mitochondrial DNA repair; IEA:EnsemblFungi.
DR   GO; GO:2000278; P:regulation of DNA biosynthetic process; IEA:EnsemblFungi.
DR   GO; GO:0000722; P:telomere maintenance via recombination; IEA:EnsemblFungi.
DR   Gene3D; 3.30.390.80; -; 1.
DR   InterPro; IPR041247; Rad52_fam.
DR   InterPro; IPR007232; Rad52_Rad59_Rad22.
DR   InterPro; IPR042525; Rad52_Rad59_Rad22_sf.
DR   InterPro; IPR016810; Rad59.
DR   PANTHER; PTHR12132; PTHR12132; 1.
DR   PANTHER; PTHR12132:SF2; PTHR12132:SF2; 1.
DR   Pfam; PF04098; Rad52_Rad22; 1.
DR   PIRSF; PIRSF022936; RAD59_fungi; 1.
PE   3: Inferred from homology;
KW   DNA damage; DNA recombination; DNA repair; Nucleus; Reference proteome.
FT   CHAIN           1..212
FT                   /note="DNA repair protein RAD59"
FT                   /id="PRO_0000173895"
SQ   SEQUENCE   212 AA;  23318 MW;  D8A1914A95FF8B45 CRC64;
     MDGKVTYEGA VYSSGPGVEV GDIVFVEDWD GRPASEWSVQ RIGVLQSKIE RYTYQIYHSN
     RYGKHNLSKL IPRHVLVGFA NEVFGFDGWK TDIEFVETKD GFPGSTSSIS IADKISADSG
     GGTGALADRY TVIAEASVKV TLKDGTNTRM TGFSRATTPS KIESFNKAKK EAVNDALKKA
     LLSFEKIILE HELKTKNDFY VDGLYGSKAQ KI