ID   RAD9B_RAT               Reviewed;         398 AA.
AC   Q499V3;
DT   07-MAR-2006, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2005, sequence version 1.
DT   03-AUG-2022, entry version 86.
DE   RecName: Full=Cell cycle checkpoint control protein RAD9B;
DE   AltName: Full=DNA repair exonuclease rad9 homolog B;
GN   Name=Rad9b;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Prostate;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SUBUNIT: Interacts with HUS1, HUS1B, RAD1, RAD9A and RAD17.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the rad9 family. {ECO:0000305}.
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DR   EMBL; BC099750; AAH99750.1; -; mRNA.
DR   RefSeq; NP_001025213.1; NM_001030042.1.
DR   AlphaFoldDB; Q499V3; -.
DR   SMR; Q499V3; -.
DR   STRING; 10116.ENSRNOP00000042520; -.
DR   PhosphoSitePlus; Q499V3; -.
DR   PaxDb; Q499V3; -.
DR   GeneID; 363924; -.
DR   KEGG; rno:363924; -.
DR   UCSC; RGD:1308223; rat.
DR   CTD; 144715; -.
DR   RGD; 1308223; Rad9b.
DR   VEuPathDB; HostDB:ENSRNOG00000021480; -.
DR   eggNOG; KOG2810; Eukaryota.
DR   HOGENOM; CLU_049242_2_0_1; -.
DR   InParanoid; Q499V3; -.
DR   OMA; HTKIWSE; -.
DR   OrthoDB; 1176140at2759; -.
DR   PhylomeDB; Q499V3; -.
DR   TreeFam; TF101212; -.
DR   Reactome; R-RNO-176187; Activation of ATR in response to replication stress.
DR   Reactome; R-RNO-5685938; HDR through Single Strand Annealing (SSA).
DR   Reactome; R-RNO-5693607; Processing of DNA double-strand break ends.
DR   Reactome; R-RNO-6804756; Regulation of TP53 Activity through Phosphorylation.
DR   Reactome; R-RNO-69473; G2/M DNA damage checkpoint.
DR   PRO; PR:Q499V3; -.
DR   Proteomes; UP000002494; Chromosome 12.
DR   Bgee; ENSRNOG00000021480; Expressed in testis and 19 other tissues.
DR   Genevisible; Q499V3; RN.
DR   GO; GO:0030896; C:checkpoint clamp complex; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; ISO:RGD.
DR   GO; GO:0071479; P:cellular response to ionizing radiation; IBA:GO_Central.
DR   GO; GO:0006281; P:DNA repair; IBA:GO_Central.
DR   GO; GO:0000076; P:DNA replication checkpoint signaling; IBA:GO_Central.
DR   GO; GO:0031573; P:mitotic intra-S DNA damage checkpoint signaling; IBA:GO_Central.
DR   InterPro; IPR026584; Rad9.
DR   InterPro; IPR007268; Rad9/Ddc1.
DR   PANTHER; PTHR15237; PTHR15237; 1.
DR   Pfam; PF04139; Rad9; 1.
DR   PIRSF; PIRSF009303; Cell_cycle_RAD9; 1.
PE   2: Evidence at transcript level;
KW   Phosphoprotein; Reference proteome.
FT   CHAIN           1..398
FT                   /note="Cell cycle checkpoint control protein RAD9B"
FT                   /id="PRO_0000226701"
FT   REGION          272..359
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        272..309
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        327..343
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         349
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q6WBX7"
FT   MOD_RES         358
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q6WBX7"
SQ   SEQUENCE   398 AA;  44075 MW;  84371DB8C63FCE2C CRC64;
     MTGGQVKVFG KAIQTLSRVS DELWLDPSEK GLALRSVNSC HSTYGYVLFS SVFFQHYQWS
     PSATITDSDI PLNLNCKLAI KSILPIFRCL NYLERSIEKC TMVARSDRCR VVIQFFGRHG
     IKRTHNVYFQ DCQPLKILFE KSLCANILMI KPRLLAEAIA LLTSNQEEVT FSVTPENFCL
     KSSSGESLDL TSSVYSEMSF GPEEFDFFQV GLDTEITFCF KELKGILTFS EVMHAPIAIY
     FDFPGKPVVL SVEDMLLEAS FILATLLDYP SRTSSPQSLR LSQARRSDPT LSGAQEGKSR
     VSQTPESISR AAPKRLFPKD PPDSSSAAET RRASASQDDI SEVPESVVSD MEEGQSPSPL
     RKFSCMFFGA VSCEQQEHAN HPLGSLAVAS DSEQDASG