RADB_HALSA
ID RADB_HALSA Reviewed; 236 AA.
AC Q9HPF2;
DT 27-APR-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 111.
DE RecName: Full=DNA repair and recombination protein RadB;
GN Name=radB; Synonyms=radA2; OrderedLocusNames=VNG_1665G;
OS Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)
OS (Halobacterium halobium).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Halobacteriaceae; Halobacterium.
OX NCBI_TaxID=64091;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700922 / JCM 11081 / NRC-1;
RX PubMed=11016950; DOI=10.1073/pnas.190337797;
RA Ng W.V., Kennedy S.P., Mahairas G.G., Berquist B., Pan M., Shukla H.D.,
RA Lasky S.R., Baliga N.S., Thorsson V., Sbrogna J., Swartzell S., Weir D.,
RA Hall J., Dahl T.A., Welti R., Goo Y.A., Leithauser B., Keller K., Cruz R.,
RA Danson M.J., Hough D.W., Maddocks D.G., Jablonski P.E., Krebs M.P.,
RA Angevine C.M., Dale H., Isenbarger T.A., Peck R.F., Pohlschroder M.,
RA Spudich J.L., Jung K.-H., Alam M., Freitas T., Hou S., Daniels C.J.,
RA Dennis P.P., Omer A.D., Ebhardt H., Lowe T.M., Liang P., Riley M., Hood L.,
RA DasSarma S.;
RT "Genome sequence of Halobacterium species NRC-1.";
RL Proc. Natl. Acad. Sci. U.S.A. 97:12176-12181(2000).
CC -!- FUNCTION: Involved in DNA repair and in homologous recombination. May
CC regulate the cleavage reactions of the branch-structured DNA. Has a
CC very weak ATPase activity that is not stimulated by DNA. Binds DNA but
CC does not promote DNA strands exchange (By similarity). {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the eukaryotic RecA-like protein family. RadB
CC subfamily. {ECO:0000305}.
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DR EMBL; AE004437; AAG19917.1; -; Genomic_DNA.
DR PIR; A84319; A84319.
DR RefSeq; WP_010903214.1; NC_002607.1.
DR AlphaFoldDB; Q9HPF2; -.
DR SMR; Q9HPF2; -.
DR STRING; 64091.VNG_1665G; -.
DR PaxDb; Q9HPF2; -.
DR EnsemblBacteria; AAG19917; AAG19917; VNG_1665G.
DR GeneID; 5953068; -.
DR GeneID; 62887065; -.
DR KEGG; hal:VNG_1665G; -.
DR PATRIC; fig|64091.14.peg.1268; -.
DR HOGENOM; CLU_041732_2_0_2; -.
DR InParanoid; Q9HPF2; -.
DR OMA; GNTLEHW; -.
DR OrthoDB; 93716at2157; -.
DR PhylomeDB; Q9HPF2; -.
DR Proteomes; UP000000554; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0003684; F:damaged DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-UniRule.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.50.300; -; 1.
DR HAMAP; MF_00350; RadB; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013632; DNA_recomb/repair_Rad51_C.
DR InterPro; IPR011939; DNA_repair_and_recomb_RadB.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020588; RecA_ATP-bd.
DR Pfam; PF08423; Rad51; 1.
DR PIRSF; PIRSF003336; RadB; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR TIGRFAMs; TIGR02237; recomb_radB; 1.
DR PROSITE; PS50162; RECA_2; 1.
PE 3: Inferred from homology;
KW ATP-binding; DNA damage; DNA recombination; DNA-binding;
KW Nucleotide-binding; Reference proteome.
FT CHAIN 1..236
FT /note="DNA repair and recombination protein RadB"
FT /id="PRO_0000150112"
FT BINDING 33..40
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255"
SQ SEQUENCE 236 AA; 25065 MW; A3897850D4323B06 CRC64;
MREDDTHLPT GCGALDELLG GGVERGTVTQ LYGPPAAGKT NVALTTAVTT AAAGGLAVYV
DTEGLSLARF QQLLEARATD PEAASANVIV SDAHDFDEQA QAVRDTADFA DRADLIVVDS
VTGFYRLARG GDDTTGDALR QVADQITHLL SLARKHDLAV VVTNQVFTDV DNDSDRARPL
GGHTLAHWTG TVLRLDRFRG GTRRATLEKH RAKPDGEHAQ FQITDGGIDA ASADDY
