RADB_METMP
ID RADB_METMP Reviewed; 216 AA.
AC P0CW61; O50248;
DT 03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 03-MAY-2011, sequence version 1.
DT 03-AUG-2022, entry version 51.
DE RecName: Full=DNA repair and recombination protein RadB;
GN Name=radB; OrderedLocusNames=MMP0617;
OS Methanococcus maripaludis (strain S2 / LL).
OC Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC Methanococcaceae; Methanococcus.
OX NCBI_TaxID=267377;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S2 / LL;
RX PubMed=15466049; DOI=10.1128/jb.186.20.6956-6969.2004;
RA Hendrickson E.L., Kaul R., Zhou Y., Bovee D., Chapman P., Chung J.,
RA Conway de Macario E., Dodsworth J.A., Gillett W., Graham D.E., Hackett M.,
RA Haydock A.K., Kang A., Land M.L., Levy R., Lie T.J., Major T.A.,
RA Moore B.C., Porat I., Palmeiri A., Rouse G., Saenphimmachak C., Soell D.,
RA Van Dien S., Wang T., Whitman W.B., Xia Q., Zhang Y., Larimer F.W.,
RA Olson M.V., Leigh J.A.;
RT "Complete genome sequence of the genetically tractable hydrogenotrophic
RT methanogen Methanococcus maripaludis.";
RL J. Bacteriol. 186:6956-6969(2004).
CC -!- FUNCTION: Involved in DNA repair and in homologous recombination. May
CC regulate the cleavage reactions of the branch-structured DNA. Has a
CC very weak ATPase activity that is not stimulated by DNA. Binds DNA but
CC does not promote DNA strands exchange (By similarity). {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the eukaryotic RecA-like protein family. RadB
CC subfamily. {ECO:0000305}.
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DR EMBL; BX950229; CAF30173.1; -; Genomic_DNA.
DR RefSeq; WP_011170561.1; NC_005791.1.
DR AlphaFoldDB; P0CW61; -.
DR SMR; P0CW61; -.
DR STRING; 267377.MMP0617; -.
DR EnsemblBacteria; CAF30173; CAF30173; MMP0617.
DR GeneID; 41279084; -.
DR KEGG; mmp:MMP0617; -.
DR PATRIC; fig|267377.15.peg.632; -.
DR eggNOG; arCOG00417; Archaea.
DR HOGENOM; CLU_041732_2_0_2; -.
DR OMA; GNTLEHW; -.
DR OrthoDB; 93716at2157; -.
DR BioCyc; MMAR267377:MMP_RS03245-MON; -.
DR Proteomes; UP000000590; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0003684; F:damaged DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-UniRule.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.50.300; -; 1.
DR HAMAP; MF_00350; RadB; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013632; DNA_recomb/repair_Rad51_C.
DR InterPro; IPR011939; DNA_repair_and_recomb_RadB.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020588; RecA_ATP-bd.
DR Pfam; PF08423; Rad51; 1.
DR PIRSF; PIRSF003336; RadB; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR TIGRFAMs; TIGR02237; recomb_radB; 1.
DR PROSITE; PS50162; RECA_2; 1.
PE 3: Inferred from homology;
KW ATP-binding; DNA damage; DNA recombination; DNA-binding;
KW Nucleotide-binding; Reference proteome.
FT CHAIN 1..216
FT /note="DNA repair and recombination protein RadB"
FT /id="PRO_0000408225"
FT BINDING 20..27
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255"
SQ SEQUENCE 216 AA; 24455 MW; 5DF0B8AFE3C70649 CRC64;
MLEELLNGNI EKKTITQIYG PPGVGKTNIC IISMLKAIEN GKNVVYIDTE GSLSIERIKQ
LSGKDCDELL KNIIIYEPSS FEEQSEALEK IFLLENVGLI IIDGIVSLYR LELCDKINEN
TKLNRMLGKQ ISNLLKVSRQ KNSGILITNQ VKDSINGIEP AGGRLLEYWS KSIIKIEKSE
SIRKLTLEKH RHAKEGENLR FKILQNGLEI INKSYQ