ID   RADB_METST              Reviewed;         232 AA.
AC   Q2NHD1;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   07-FEB-2006, sequence version 1.
DT   03-AUG-2022, entry version 90.
DE   RecName: Full=DNA repair and recombination protein RadB {ECO:0000255|HAMAP-Rule:MF_00350};
GN   Name=radB {ECO:0000255|HAMAP-Rule:MF_00350}; OrderedLocusNames=Msp_0369;
OS   Methanosphaera stadtmanae (strain ATCC 43021 / DSM 3091 / JCM 11832 /
OS   MCB-3).
OC   Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC   Methanobacteriales; Methanobacteriaceae; Methanosphaera.
OX   NCBI_TaxID=339860;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43021 / DSM 3091 / JCM 11832 / MCB-3;
RX   PubMed=16385054; DOI=10.1128/jb.188.2.642-658.2006;
RA   Fricke W.F., Seedorf H., Henne A., Kruer M., Liesegang H., Hedderich R.,
RA   Gottschalk G., Thauer R.K.;
RT   "The genome sequence of Methanosphaera stadtmanae reveals why this human
RT   intestinal archaeon is restricted to methanol and H2 for methane formation
RT   and ATP synthesis.";
RL   J. Bacteriol. 188:642-658(2006).
CC   -!- FUNCTION: Involved in DNA repair and in homologous recombination. May
CC       regulate the cleavage reactions of the branch-structured DNA. Has a
CC       very weak ATPase activity that is not stimulated by DNA. Binds DNA but
CC       does not promote DNA strands exchange. {ECO:0000255|HAMAP-
CC       Rule:MF_00350}.
CC   -!- SIMILARITY: Belongs to the eukaryotic RecA-like protein family. RadB
CC       subfamily. {ECO:0000255|HAMAP-Rule:MF_00350}.
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DR   EMBL; CP000102; ABC56772.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q2NHD1; -.
DR   SMR; Q2NHD1; -.
DR   STRING; 339860.Msp_0369; -.
DR   EnsemblBacteria; ABC56772; ABC56772; Msp_0369.
DR   KEGG; mst:Msp_0369; -.
DR   eggNOG; arCOG00417; Archaea.
DR   HOGENOM; CLU_041732_2_0_2; -.
DR   OMA; GNTLEHW; -.
DR   Proteomes; UP000001931; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR   GO; GO:0003684; F:damaged DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003697; F:single-stranded DNA binding; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-UniRule.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.40.50.300; -; 1.
DR   HAMAP; MF_00350; RadB; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR013632; DNA_recomb/repair_Rad51_C.
DR   InterPro; IPR013765; DNA_recomb/repair_RecA.
DR   InterPro; IPR011939; DNA_repair_and_recomb_RadB.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR020588; RecA_ATP-bd.
DR   Pfam; PF08423; Rad51; 1.
DR   PIRSF; PIRSF003336; RadB; 1.
DR   PRINTS; PR00142; RECA.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR02237; recomb_radB; 1.
DR   PROSITE; PS50162; RECA_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding; DNA damage; DNA recombination; DNA-binding;
KW   Nucleotide-binding; Reference proteome.
FT   CHAIN           1..232
FT                   /note="DNA repair and recombination protein RadB"
FT                   /id="PRO_1000006936"
SQ   SEQUENCE   232 AA;  25795 MW;  F2D34732E73F5C50 CRC64;
     MKTLSDISES VLIPTNSSLD KLLGGGIEKG CITQFYGPPG SGKTNIALKI LYEATKNGSK
     AIYMDTEGGL SLERIQQIAG TDFGSISKNI YILEPKSFDE QILDIQNIED ILKKDKSIDM
     LIIDSIVALY RVEDGDPSEI NKRLGRLMAK LLRLSREYNV AIVITNQIYS PFDSDDLIIE
     PIGGTVLKYW SKIIIEIEKS VDSLKRTATL QRHKTKAPGQ SIKFEIIDRG II