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RADB_THESM
ID   RADB_THESM              Reviewed;         228 AA.
AC   C6A0N1;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-SEP-2009, sequence version 1.
DT   03-AUG-2022, entry version 70.
DE   RecName: Full=DNA repair and recombination protein RadB {ECO:0000255|HAMAP-Rule:MF_00350};
GN   Name=radB {ECO:0000255|HAMAP-Rule:MF_00350}; OrderedLocusNames=TSIB_0108;
OS   Thermococcus sibiricus (strain DSM 12597 / MM 739).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Thermococcus.
OX   NCBI_TaxID=604354;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 12597 / MM 739;
RX   PubMed=19447963; DOI=10.1128/aem.00718-09;
RA   Mardanov A.V., Ravin N.V., Svetlitchnyi V.A., Beletsky A.V.,
RA   Miroshnichenko M.L., Bonch-Osmolovskaya E.A., Skryabin K.G.;
RT   "Metabolic versatility and indigenous origin of the archaeon Thermococcus
RT   sibiricus, isolated from a siberian oil reservoir, as revealed by genome
RT   analysis.";
RL   Appl. Environ. Microbiol. 75:4580-4588(2009).
CC   -!- FUNCTION: Involved in DNA repair and in homologous recombination. May
CC       regulate the cleavage reactions of the branch-structured DNA. Has a
CC       very weak ATPase activity that is not stimulated by DNA. Binds DNA but
CC       does not promote DNA strands exchange. {ECO:0000255|HAMAP-
CC       Rule:MF_00350}.
CC   -!- SIMILARITY: Belongs to the eukaryotic RecA-like protein family. RadB
CC       subfamily. {ECO:0000255|HAMAP-Rule:MF_00350}.
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DR   EMBL; CP001463; ACS89176.1; -; Genomic_DNA.
DR   RefSeq; WP_012766137.1; NC_012883.1.
DR   AlphaFoldDB; C6A0N1; -.
DR   SMR; C6A0N1; -.
DR   STRING; 604354.TSIB_0108; -.
DR   EnsemblBacteria; ACS89176; ACS89176; TSIB_0108.
DR   GeneID; 8095077; -.
DR   KEGG; tsi:TSIB_0108; -.
DR   eggNOG; arCOG00417; Archaea.
DR   HOGENOM; CLU_041732_2_0_2; -.
DR   OMA; GNTLEHW; -.
DR   OrthoDB; 93716at2157; -.
DR   Proteomes; UP000009079; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR   GO; GO:0003684; F:damaged DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-UniRule.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.40.50.300; -; 1.
DR   HAMAP; MF_00350; RadB; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR013632; DNA_recomb/repair_Rad51_C.
DR   InterPro; IPR011939; DNA_repair_and_recomb_RadB.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR020588; RecA_ATP-bd.
DR   Pfam; PF08423; Rad51; 1.
DR   PIRSF; PIRSF003336; RadB; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR02237; recomb_radB; 1.
DR   PROSITE; PS50162; RECA_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding; DNA damage; DNA recombination; DNA-binding;
KW   Nucleotide-binding; Reference proteome.
FT   CHAIN           1..228
FT                   /note="DNA repair and recombination protein RadB"
FT                   /id="PRO_1000205340"
SQ   SEQUENCE   228 AA;  25659 MW;  1B741020BA3F96E9 CRC64;
     MLTTGSKNLD ALLGGGIDKG ILTQVYGPFA TGKTTLAMQI GLLNEGKVAY IDTEGGFSPE
     RLAKMVESRG MDSNSTLQKF LIFEAFDFKE QKKTISNLKK IVNEKFSMIV VDSITNHYRV
     EEKKSSMTTD LGKQLQVLLW LARKYNLAVI VTNQVYFDSK QNALKPLAEH IMGYKCKDIL
     RLEKLRPGLR IAVLERHRFK PEGGIVHFEI TDKGIEDIEK IKSSQTTL
 
 
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