RADL2_ARATH
ID RADL2_ARATH Reviewed; 101 AA.
AC Q9SIJ5;
DT 03-OCT-2012, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 144.
DE RecName: Full=Protein RADIALIS-like 2;
DE Short=AtRL2;
DE Short=Protein RAD-like 2;
DE AltName: Full=Protein MATERNAL EFFECT EMBRYO ARREST 3;
DE AltName: Full=Protein RADIALIS-LIKE SANT/MYB 1;
DE Short=Protein RSM1;
GN Name=RL2; Synonyms=MEE3, RMS1; OrderedLocusNames=At2g21650;
GN ORFNames=F2G1.8;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Qu L.-J., Gu H.;
RT "The MYB transcription factor family in Arabidopsis: a genome-wide cloning
RT and expression pattern analysis.";
RL Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP FUNCTION, AND DISRUPTION PHENOTYPE.
RX PubMed=15634699; DOI=10.1242/dev.01595;
RA Pagnussat G.C., Yu H.-J., Ngo Q.A., Rajani S., Mayalagu S., Johnson C.S.,
RA Capron A., Xie L.-F., Ye D., Sundaresan V.;
RT "Genetic and molecular identification of genes required for female
RT gametophyte development and function in Arabidopsis.";
RL Development 132:603-614(2005).
RN [7]
RP GENE FAMILY.
RX PubMed=16463103; DOI=10.1007/s11103-005-2910-y;
RA Chen Y., Yang X., He K., Liu M., Li J., Gao Z., Lin Z., Zhang Y., Wang X.,
RA Qiu X., Shen Y., Zhang L., Deng X., Luo J., Deng X.-W., Chen Z., Gu H.,
RA Qu L.-J.;
RT "The MYB transcription factor superfamily of Arabidopsis: expression
RT analysis and phylogenetic comparison with the rice MYB family.";
RL Plant Mol. Biol. 60:107-124(2006).
RN [8]
RP GENE FAMILY, AND TISSUE SPECIFICITY.
RX PubMed=17672842; DOI=10.1111/j.1365-313x.2007.03222.x;
RA Baxter C.E.L., Costa M.M.R., Coen E.S.;
RT "Diversification and co-option of RAD-like genes in the evolution of floral
RT asymmetry.";
RL Plant J. 52:105-113(2007).
RN [9]
RP GENE FAMILY.
RX PubMed=18838801; DOI=10.1271/bbb.80348;
RA Hamaguchi A., Yamashino T., Koizumi N., Kiba T., Kojima M., Sakakibara H.,
RA Mizuno T.;
RT "A small subfamily of Arabidopsis RADIALIS-LIKE SANT/MYB genes: a link to
RT HOOKLESS1-mediated signal transduction during early morphogenesis.";
RL Biosci. Biotechnol. Biochem. 72:2687-2696(2008).
CC -!- FUNCTION: Probable transcription factor. Required for female
CC gametophyte development. {ECO:0000269|PubMed:15634699}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- TISSUE SPECIFICITY: Expressed in the funiculus of ovules and in
CC embryos. In young ovules, expression is observed in the adaxial side of
CC the funiculus (the stalk connecting the embryo sac to the placenta).
CC Also expressed in heart-stage embryos, in the cortex and endodermis of
CC the hypocotyl region but not in the cotyledons, shoot and root apical
CC meristems, provasculature or epidermis. Not detected in young
CC seedlings, mature roots or in young floral primordia.
CC {ECO:0000269|PubMed:17672842}.
CC -!- DISRUPTION PHENOTYPE: Endosperm development arrested.
CC {ECO:0000269|PubMed:15634699}.
CC -!- MISCELLANEOUS: Assigned as a member of the MYB-related gene family, I-
CC box-binding-like subfamily. {ECO:0000305|PubMed:16463103}.
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DR EMBL; AY519526; AAS09996.1; -; mRNA.
DR EMBL; AC007119; AAD23640.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC07207.1; -; Genomic_DNA.
DR EMBL; BT008554; AAP40381.1; -; mRNA.
DR EMBL; BT008698; AAP40504.1; -; mRNA.
DR EMBL; AK229516; BAF01371.1; -; mRNA.
DR PIR; G84603; G84603.
DR RefSeq; NP_179759.1; NM_127736.4.
DR AlphaFoldDB; Q9SIJ5; -.
DR SMR; Q9SIJ5; -.
DR BioGRID; 2056; 8.
DR IntAct; Q9SIJ5; 5.
DR STRING; 3702.AT2G21650.1; -.
DR PaxDb; Q9SIJ5; -.
DR PRIDE; Q9SIJ5; -.
DR ProteomicsDB; 236563; -.
DR EnsemblPlants; AT2G21650.1; AT2G21650.1; AT2G21650.
DR GeneID; 816703; -.
DR Gramene; AT2G21650.1; AT2G21650.1; AT2G21650.
DR KEGG; ath:AT2G21650; -.
DR Araport; AT2G21650; -.
DR TAIR; locus:2049374; AT2G21650.
DR eggNOG; KOG0724; Eukaryota.
DR HOGENOM; CLU_137624_1_2_1; -.
DR InParanoid; Q9SIJ5; -.
DR OMA; VKIHYEK; -.
DR OrthoDB; 1583899at2759; -.
DR PhylomeDB; Q9SIJ5; -.
DR PRO; PR:Q9SIJ5; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9SIJ5; baseline and differential.
DR Genevisible; Q9SIJ5; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0009793; P:embryo development ending in seed dormancy; IMP:TAIR.
DR GO; GO:0009630; P:gravitropism; IMP:TAIR.
DR GO; GO:0010114; P:response to red light; IMP:TAIR.
DR CDD; cd00167; SANT; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR044636; RADIALIS-like.
DR InterPro; IPR001005; SANT/Myb.
DR PANTHER; PTHR43952; PTHR43952; 1.
DR SMART; SM00717; SANT; 1.
DR SUPFAM; SSF46689; SSF46689; 1.
PE 2: Evidence at transcript level;
KW Nucleus; Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..101
FT /note="Protein RADIALIS-like 2"
FT /id="PRO_0000419442"
FT DOMAIN 9..64
FT /note="SANT"
FT REGION 69..101
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 84..101
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 101 AA; 11508 MW; 83FCE4637D687C32 CRC64;
MASGSMSSYG SGSWTVKQNK AFERALAVYD QDTPDRWHNV ARAVGGKTPE EAKRQYDLLV
RDIESIENGH VPFPDYKTTT GNSNRGRLRD EEKRMRSMKL Q
