ID   RAI2_MOUSE              Reviewed;         529 AA.
AC   Q9QVY8; Q3UPL8;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   27-JUL-2011, sequence version 2.
DT   03-AUG-2022, entry version 103.
DE   RecName: Full=Retinoic acid-induced protein 2;
DE   AltName: Full=3f8;
GN   Name=Rai2;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=8314004; DOI=10.1006/dbio.1994.1056;
RA   Jonk L.J.C., de Jonge M.E., Vervaart J.M., Wissink S., Kruijer W.;
RT   "Isolation and developmental expression of retinoic-acid-induced genes.";
RL   Dev. Biol. 161:604-614(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=C57BL/6J; TISSUE=Olfactory bulb;
RX   PubMed=16141072; DOI=10.1126/science.1112014;
RA   Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA   Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA   Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA   Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA   Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA   Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA   Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA   Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA   Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA   Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA   Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA   Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA   Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA   Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA   Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA   Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA   Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA   Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA   Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA   Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA   Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA   Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA   Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA   Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA   Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA   van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA   Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA   Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA   Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA   Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA   Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA   Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA   Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA   Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT   "The transcriptional landscape of the mammalian genome.";
RL   Science 309:1559-1563(2005).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J;
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA   Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA   Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA   Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA   Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA   Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of the
RT   mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
CC   -!- INDUCTION: By retinoic acid.
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DR   EMBL; X76652; -; NOT_ANNOTATED_CDS; mRNA.
DR   EMBL; AK143442; BAE25377.1; -; mRNA.
DR   EMBL; AL732391; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   CCDS; CCDS30507.1; -.
DR   RefSeq; NP_001096837.1; NM_001103367.1.
DR   RefSeq; NP_940801.2; NM_198409.3.
DR   AlphaFoldDB; Q9QVY8; -.
DR   STRING; 10090.ENSMUSP00000051618; -.
DR   iPTMnet; Q9QVY8; -.
DR   PhosphoSitePlus; Q9QVY8; -.
DR   EPD; Q9QVY8; -.
DR   PaxDb; Q9QVY8; -.
DR   PRIDE; Q9QVY8; -.
DR   ProteomicsDB; 254977; -.
DR   Antibodypedia; 35327; 41 antibodies from 19 providers.
DR   Ensembl; ENSMUST00000061514; ENSMUSP00000051618; ENSMUSG00000043518.
DR   Ensembl; ENSMUST00000112338; ENSMUSP00000107957; ENSMUSG00000043518.
DR   GeneID; 24004; -.
DR   KEGG; mmu:24004; -.
DR   UCSC; uc009uua.2; mouse.
DR   CTD; 10742; -.
DR   MGI; MGI:1344378; Rai2.
DR   VEuPathDB; HostDB:ENSMUSG00000043518; -.
DR   eggNOG; ENOG502RCMZ; Eukaryota.
DR   GeneTree; ENSGT00940000154164; -.
DR   HOGENOM; CLU_044853_0_0_1; -.
DR   InParanoid; Q9QVY8; -.
DR   OMA; EFSRQHK; -.
DR   OrthoDB; 956789at2759; -.
DR   TreeFam; TF331261; -.
DR   BioGRID-ORCS; 24004; 0 hits in 71 CRISPR screens.
DR   ChiTaRS; Rai2; mouse.
DR   PRO; PR:Q9QVY8; -.
DR   Proteomes; UP000000589; Chromosome X.
DR   RNAct; Q9QVY8; protein.
DR   Bgee; ENSMUSG00000043518; Expressed in myocardium of ventricle and 197 other tissues.
DR   Genevisible; Q9QVY8; MM.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0048513; P:animal organ development; IBA:GO_Central.
DR   InterPro; IPR026092; RAI2/SOBP.
DR   PANTHER; PTHR23186; PTHR23186; 1.
DR   Pfam; PF15279; SOBP; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..529
FT                   /note="Retinoic acid-induced protein 2"
FT                   /id="PRO_0000097162"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          400..419
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        55
FT                   /note="A -> G (in Ref. 1; X76652)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        175..176
FT                   /note="SQ -> RK (in Ref. 1; X76652)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   529 AA;  57123 MW;  471A907660BED55D CRC64;
     MDDLQSQNLS MDMTDSPPTL ANNRLENRMA QLITTEAWNI NSTDLVKKAL VTVPAPSILN
     PPAESQSGMA LKVAATVLQP LCLGESPVVM PIHMQVEGSS APELNPNGNA TYVMTTQGPV
     QLPVVLEQHV FQHLNSPLVL PQEAPCSSNA IHNNLFQGAE DSEAQPQLLD LRIPSQPQEP
     ALPFEAVLQN LFPTQGSLGP PPCQPPPGYA PVPPQPFNSP LSPLVPPATL LVPYPVIVPL
     PVPVPIPIPV PVPQSTESKF SPTFPKPPSS FGLHSFKGTQ TTLEKDELKP LDILQSKEYF
     QLSRHTVIKM GSENEALDLS MKSVPWLKAG EASPPVFQED AALDLSLAAH RKAEAPPETL
     YNNSGSADIQ GHTILEKLSS GMEMPFAPAK CSEASAMMES HSSNSNGTEM VSQPSHPGSE
     LKAENNIEIL SESQAAKVIV SVEDAVPAIF CGKIKGLSGV STKNFSFKRE DSVLQGYDIN
     SQGEESLGNA EPLRKPIKNR SIKLKKVNSQ EIHMLPIKKQ RLATFFPRK