ID   RAII_RHIET              Reviewed;         212 AA.
AC   O54451;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1998, sequence version 1.
DT   25-MAY-2022, entry version 72.
DE   RecName: Full=Acyl-homoserine-lactone synthase;
DE            EC=2.3.1.184;
DE   AltName: Full=Autoinducer synthesis protein RaiI;
GN   Name=raiI;
OS   Rhizobium etli.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Rhizobium/Agrobacterium group; Rhizobium.
OX   NCBI_TaxID=29449;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=CNPAF512;
RX   PubMed=9473034; DOI=10.1128/jb.180.4.815-821.1998;
RA   Rosemeyer V., Michiels J., Verreth C., Vanderleyden J.;
RT   "luxI- and luxR-homologous genes of Rhizobium etli CNPAF512 contribute to
RT   synthesis of autoinducer molecules and nodulation of Phaseolus vulgaris.";
RL   J. Bacteriol. 180:815-821(1998).
CC   -!- FUNCTION: Required for the synthesis of autoinducer molecules which
CC       bind to RaiR and that are involved in the restriction of nodule number.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a fatty acyl-[ACP] + S-adenosyl-L-methionine = an N-acyl-L-
CC         homoserine lactone + H(+) + holo-[ACP] + S-methyl-5'-thioadenosine;
CC         Xref=Rhea:RHEA:10096, Rhea:RHEA-COMP:9685, Rhea:RHEA-COMP:14125,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:17509, ChEBI:CHEBI:55474,
CC         ChEBI:CHEBI:59789, ChEBI:CHEBI:64479, ChEBI:CHEBI:138651;
CC         EC=2.3.1.184;
CC   -!- SIMILARITY: Belongs to the autoinducer synthase family.
CC       {ECO:0000255|PROSITE-ProRule:PRU00533}.
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DR   EMBL; AY708656; AAC38172.1; -; Genomic_DNA.
DR   AlphaFoldDB; O54451; -.
DR   SMR; O54451; -.
DR   STRING; 491916.RHECIAT_PC0000663; -.
DR   GO; GO:0061579; F:N-acyl homoserine lactone synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009372; P:quorum sensing; IEA:UniProtKB-KW.
DR   InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR   InterPro; IPR018311; Autoind_synth_CS.
DR   InterPro; IPR001690; Autoind_synthase.
DR   PANTHER; PTHR39322; PTHR39322; 1.
DR   Pfam; PF00765; Autoind_synth; 1.
DR   PRINTS; PR01549; AUTOINDCRSYN.
DR   SUPFAM; SSF55729; SSF55729; 1.
DR   PROSITE; PS00949; AUTOINDUCER_SYNTH_1; 1.
DR   PROSITE; PS51187; AUTOINDUCER_SYNTH_2; 1.
PE   3: Inferred from homology;
KW   Autoinducer synthesis; Nodulation; Quorum sensing; S-adenosyl-L-methionine;
KW   Transferase.
FT   CHAIN           1..212
FT                   /note="Acyl-homoserine-lactone synthase"
FT                   /id="PRO_0000210893"
SQ   SEQUENCE   212 AA;  24209 MW;  5107B26FE034E86B CRC64;
     MLRILTKDML ETDRRAFDEM FRARAAVFRD RLGWQVDVRD QWERDRYDEA EDPVYLVTQQ
     PSGTLTGSLR LLPTTGATML KSEFRHFFDQ PIDVDSPTTW ECTRFCLHPH AGDMKQSRAV
     ATELLSGLCD LALDTGIENI VGVYDVAMVA VYRRIGWRPT PLARSRPEIG KLYVGLWDVT
     ADNCRTLRAN LSRLLEQASP YPARVLVDGG MR