ID   RAL_BPPH3               Reviewed;          76 AA.
AC   P07235;
DT   01-APR-1988, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1996, sequence version 2.
DT   03-AUG-2022, entry version 47.
DE   RecName: Full=Restriction inhibitor protein ral;
DE   AltName: Full=Antirestriction protein;
GN   Name=ral;
OS   Enterobacteria phage phi21 (Bacteriophage phi-21).
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Caudovirales; Siphoviridae.
OX   NCBI_TaxID=10737;
OH   NCBI_TaxID=1423; Bacillus subtilis.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=3157001; DOI=10.1016/0022-2836(85)90325-0;
RA   Franklin N.C.;
RT   "Conservation of genome form but not sequence in the transcription
RT   antitermination determinants of bacteriophages lambda, phi 21 and P22.";
RL   J. Mol. Biol. 181:75-84(1985).
CC   -!- FUNCTION: Ral interferes with the cleavage of DNA by E.coli EcoK
CC       restriction-modification system, by modifying the activity of the host
CC       methylase. This modulation allows incoming, unmodified phages to escape
CC       the host's restriction system. {ECO:0000250|UniProtKB:P03703}.
CC   -!- SIMILARITY: Belongs to the lambda phage ral family. {ECO:0000305}.
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DR   EMBL; K03422; AAD15034.1; -; Genomic_DNA.
DR   PRIDE; P07235; -.
DR   GO; GO:0099018; P:evasion by virus of host restriction-modification system; IEA:UniProtKB-KW.
DR   InterPro; IPR022759; Antirestriction_protein_Ral.
DR   Pfam; PF11058; Ral; 1.
PE   3: Inferred from homology;
KW   Host-virus interaction; Restriction-modification system evasion by virus.
FT   CHAIN           1..76
FT                   /note="Restriction inhibitor protein ral"
FT                   /id="PRO_0000077698"
SQ   SEQUENCE   76 AA;  8741 MW;  3224550CA1ABAE86 CRC64;
     MTTTIDKNQW CGQFKRCNGC KLQSECMVKP EEMFPVMEDG KYVDKWAIRT TAMIARELGK
     QLDEDARLCS LSVFDA