ID   RANG_DICDI              Reviewed;         194 AA.
AC   Q54KD9;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 101.
DE   RecName: Full=Ran-specific GTPase-activating protein homolog;
DE   AltName: Full=Ran-binding protein 1;
DE            Short=RanBP1;
GN   Name=ranbp1; ORFNames=DDB_G0287391;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   STRAIN=AX2;
RX   PubMed=16926386; DOI=10.1074/mcp.m600113-mcp200;
RA   Gotthardt D., Blancheteau V., Bosserhoff A., Ruppert T., Delorenzi M.,
RA   Soldati T.;
RT   "Proteomics fingerprinting of phagosome maturation and evidence for the
RT   role of a Galpha during uptake.";
RL   Mol. Cell. Proteomics 5:2228-2243(2006).
CC   -!- SIMILARITY: Belongs to the RANBP1 family. {ECO:0000305}.
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DR   EMBL; AAFI02000100; EAL63763.1; -; Genomic_DNA.
DR   RefSeq; XP_637284.1; XM_632192.1.
DR   AlphaFoldDB; Q54KD9; -.
DR   SMR; Q54KD9; -.
DR   STRING; 44689.DDB0237919; -.
DR   PaxDb; Q54KD9; -.
DR   EnsemblProtists; EAL63763; EAL63763; DDB_G0287391.
DR   GeneID; 8626115; -.
DR   KEGG; ddi:DDB_G0287391; -.
DR   dictyBase; DDB_G0287391; ranbp1.
DR   eggNOG; KOG0864; Eukaryota.
DR   HOGENOM; CLU_067861_0_1_1; -.
DR   InParanoid; Q54KD9; -.
DR   OMA; HLEQTGN; -.
DR   PhylomeDB; Q54KD9; -.
DR   PRO; PR:Q54KD9; -.
DR   Proteomes; UP000002195; Chromosome 5.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005643; C:nuclear pore; IBA:GO_Central.
DR   GO; GO:0140220; C:pathogen-containing vacuole; IDA:dictyBase.
DR   GO; GO:0045335; C:phagocytic vesicle; HDA:dictyBase.
DR   GO; GO:0031267; F:small GTPase binding; ISS:dictyBase.
DR   GO; GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.
DR   GO; GO:0050790; P:regulation of catalytic activity; IEA:GOC.
DR   CDD; cd13179; RanBD_RanBP1; 1.
DR   Gene3D; 2.30.29.30; -; 1.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR000156; Ran_bind_dom.
DR   InterPro; IPR045255; RanBP1-like.
DR   InterPro; IPR045256; RanBP1_RanBD.
DR   InterPro; IPR000697; WH1/EVH1_dom.
DR   PANTHER; PTHR23138; PTHR23138; 1.
DR   Pfam; PF00638; Ran_BP1; 1.
DR   SMART; SM00160; RanBD; 1.
DR   PROSITE; PS50196; RANBD1; 1.
DR   PROSITE; PS50229; WH1; 1.
PE   1: Evidence at protein level;
KW   Reference proteome.
FT   CHAIN           1..194
FT                   /note="Ran-specific GTPase-activating protein homolog"
FT                   /id="PRO_0000330896"
FT   DOMAIN          42..188
FT                   /note="RanBD1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00164"
FT   REGION          1..36
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..31
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   194 AA;  22421 MW;  4BF051C78E457289 CRC64;
     MSEVEKKEEE TTTTTTVEKT EEKKEETSSF APAAEIKEYA ADVEPNVEYE ATLKRDVVEV
     KTNEENEDTL FEIRAKLYRF DTDPSPQWKE RGTGNVRFLE DKDSKRIRVV MRRDKTLKVC
     LNHHISPALS LGEMTGSDKS WVWKCPKDFS DEEKPEGVEE LFAIRFATPE NAGLFKTEFQ
     KCQAKNEAIE KKTE