ID   RANT_BPP22              Reviewed;         300 AA.
AC   P03037; Q7PCJ2;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=Antirepressor protein ant;
GN   Name=ant;
OS   Salmonella phage P22 (Bacteriophage P22).
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Caudovirales; Podoviridae; Lederbergvirus.
OX   NCBI_TaxID=10754;
OH   NCBI_TaxID=90371; Salmonella typhimurium.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PROTEIN SEQUENCE OF 1-18.
RX   PubMed=6350606; DOI=10.1016/s0022-2836(83)80070-9;
RA   Sauer R.T., Krovatin W., Deanda J., Youderian P., Susskind M.M.;
RT   "Primary structure of the immI immunity region of bacteriophage P22.";
RL   J. Mol. Biol. 168:699-713(1983).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=11053393; DOI=10.1128/jb.182.22.6472-6481.2000;
RA   Vander Byl C.S., Kropinski A.M.B.;
RT   "Sequence of the genome of Salmonella bacteriophage P22.";
RL   J. Bacteriol. 182:6472-6481(2000).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12562822; DOI=10.1128/jb.185.4.1475-1477.2003;
RA   Pedulla M.L., Ford M.E., Karthikeyan T., Houtz J.M., Hendrix R.W.,
RA   Hatfull G.F., Poteete A.R., Gilcrease E.B., Winn-Stapley D.A.,
RA   Casjens S.R.;
RT   "Corrected sequence of the bacteriophage P22 genome.";
RL   J. Bacteriol. 185:1475-1477(2003).
CC   -!- FUNCTION: This protein prevents the prophage P22 c2 repressor protein
CC       from binding to its operators and also inhibits the action of other
CC       prophage repressor proteins, including those of phages lambda and 434.
CC       The synthesis of antirepressor is negatively regulated by the protein
CC       products of the two other immI genes, mnt and arc.
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DR   EMBL; X01916; CAA25991.1; -; Genomic_DNA.
DR   EMBL; AF217253; AAF75059.1; -; Genomic_DNA.
DR   EMBL; BK000583; DAA00980.1; -; Genomic_DNA.
DR   PIR; A03573; OUBP22.
DR   RefSeq; NP_059643.1; NC_002371.2.
DR   GeneID; 1262786; -.
DR   KEGG; vg:1262786; -.
DR   Proteomes; UP000001795; Genome.
DR   Proteomes; UP000007960; Genome.
DR   InterPro; IPR018875; Antirepressor_Ant_N.
DR   InterPro; IPR018876; Phage_P22_antirepressor_C.
DR   Pfam; PF10548; P22_AR_C; 1.
DR   Pfam; PF10547; P22_AR_N; 1.
DR   PRINTS; PR01994; ANTIREPRESSR.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..300
FT                   /note="Antirepressor protein ant"
FT                   /id="PRO_0000077734"
SQ   SEQUENCE   300 AA;  34649 MW;  C43A038A0F045B12 CRC64;
     MNSIAILEAV NTSYVPFNGQ HVLTAMVAGV AYVAMKPVVD NIGLSWSSQV QKLLKMKDKF
     NYVDIDMVAG DMKKRLMGCI PLKKLNGWLF SINPEKVRAD IRDKLIKYQE ECFTVLYDYW
     TKGKAENPRK KTSVDERTPL RDAVNMLVSK KHLMYPEAYA MIHQRFNVES IEELEASQIP
     LAVEYIHRVV LEGEFIGKQE KKTNDLSAKE ANSLVWLWDY ANRSQALFRE LYPAMRQIQS
     NYSGKCYDYG HEFSYIIGIA RDVLINHTRD VDINEPDGPT NLSAWMRLKD KELPPSLHRY