RAP26_ARATH
ID RAP26_ARATH Reviewed; 192 AA.
AC Q7G1L2; O23108;
DT 21-AUG-2007, integrated into UniProtKB/Swiss-Prot.
DT 21-AUG-2007, sequence version 2.
DT 03-AUG-2022, entry version 111.
DE RecName: Full=Ethylene-responsive transcription factor RAP2-6;
DE AltName: Full=Protein RELATED TO APETALA2 6;
GN Name=RAP2-6; Synonyms=ERF108; OrderedLocusNames=At1g43160;
GN ORFNames=F1I21.18;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 29-192.
RX PubMed=9192694; DOI=10.1073/pnas.94.13.7076;
RA Okamuro J.K., Caster B., Villarroel R., Van Montagu M., Jofuku K.D.;
RT "The AP2 domain of APETALA2 defines a large new family of DNA binding
RT proteins in Arabidopsis.";
RL Proc. Natl. Acad. Sci. U.S.A. 94:7076-7081(1997).
RN [5]
RP INDUCTION.
RX PubMed=14756769; DOI=10.1111/j.1365-313x.2003.01986.x;
RA He P., Chintamanani S., Chen Z., Zhu L., Kunkel B.N., Alfano J.R., Tang X.,
RA Zhou J.-M.;
RT "Activation of a COI1-dependent pathway in Arabidopsis by Pseudomonas
RT syringae type III effectors and coronatine.";
RL Plant J. 37:589-602(2004).
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=16407444; DOI=10.1104/pp.105.073783;
RA Nakano T., Suzuki K., Fujimura T., Shinshi H.;
RT "Genome-wide analysis of the ERF gene family in Arabidopsis and rice.";
RL Plant Physiol. 140:411-432(2006).
RN [7]
RP INDUCTION.
RX PubMed=17786451; DOI=10.1007/s00299-007-0410-z;
RA Wang Z., Cao G., Wang X., Miao J., Liu X., Chen Z., Qu L.-J., Gu H.;
RT "Identification and characterization of COI1-dependent transcription factor
RT genes involved in JA-mediated response to wounding in Arabidopsis plants.";
RL Plant Cell Rep. 27:125-135(2008).
RN [8]
RP FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, AND INDUCTION.
RX PubMed=20193749; DOI=10.1016/j.gene.2010.02.011;
RA Zhu Q., Zhang J., Gao X., Tong J., Xiao L., Li W., Zhang H.;
RT "The Arabidopsis AP2/ERF transcription factor RAP2.6 participates in ABA,
RT salt and osmotic stress responses.";
RL Gene 457:1-12(2010).
RN [9]
RP FUNCTION, TISSUE SPECIFICITY, AND INDUCTION.
RX PubMed=21069430; DOI=10.1007/s11103-010-9711-7;
RA Krishnaswamy S., Verma S., Rahman M.H., Kav N.N.;
RT "Functional characterization of four APETALA2-family genes (RAP2.6,
RT RAP2.6L, DREB19 and DREB26) in Arabidopsis.";
RL Plant Mol. Biol. 75:107-127(2011).
RN [10]
RP FUNCTION, TISSUE SPECIFICITY, AND INDUCTION.
RX PubMed=23510309; DOI=10.1186/1471-2229-13-47;
RA Ali M.A., Abbas A., Kreil D.P., Bohlmann H.;
RT "Overexpression of the transcription factor RAP2.6 leads to enhanced
RT callose deposition in syncytia and enhanced resistance against the beet
RT cyst nematode Heterodera schachtii in Arabidopsis roots.";
RL BMC Plant Biol. 13:47-47(2013).
CC -!- FUNCTION: Transcriptional activator involved in the regulation of plant
CC development and tolerance to abiotic stresses (PubMed:21069430). Binds
CC to the GCC-box pathogenesis-related promoter element and the cis-
CC element CE1 (coupling element 1). Involved in the regulation of gene
CC expression in response to abiotic stresses, possibly through the
CC abscisic acid (ABA) signaling pathway (PubMed:20193749). Involved in
CC resistance to the beet cyst nematode Heterodera schachtii in roots. May
CC promote callose deposition at syncytia which may interfere with
CC nutrient import into syncytia and inhibit the development of nematodes
CC (PubMed:23510309). {ECO:0000269|PubMed:20193749,
CC ECO:0000269|PubMed:21069430, ECO:0000269|PubMed:23510309}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00366,
CC ECO:0000269|PubMed:20193749}.
CC -!- TISSUE SPECIFICITY: Expressed in petals, carpels and valves of immature
CC siliques (PubMed:21069430). Expressed at high levels in stems.
CC Expressed in roots, rosette leaves, flowers and siliques
CC (PubMed:20193749, PubMed:23510309). {ECO:0000269|PubMed:20193749,
CC ECO:0000269|PubMed:21069430, ECO:0000269|PubMed:23510309}.
CC -!- INDUCTION: Induced by salt, heat and drought stresses
CC (PubMed:21069430). Induced by osmotic stress (PubMed:20193749). Induced
CC by jasmonate (JA) (PubMed:21069430, PubMed:14756769, PubMed:17786451).
CC Induced by salicylic acid (SA) (PubMed:14756769, PubMed:21069430).
CC Induced by abscisic acid (ABA) (PubMed:20193749, PubMed:21069430).
CC Induced by ethylene (PubMed:14756769). Induced by infection with the
CC bacterial pathogen Pseudomonas syringae pv. tomato DC3000
CC (PubMed:14756769, PubMed:23510309). Induced by the bacterial pathogen
CC Pseudomonas syringae pv. maculicola ES4326 (PubMed:14756769). Induced
CC by wounding (PubMed:17786451). Down-regulated by infection with the
CC beet cyst nematode Heterodera schachtii (PubMed:23510309).
CC {ECO:0000269|PubMed:14756769, ECO:0000269|PubMed:17786451,
CC ECO:0000269|PubMed:20193749, ECO:0000269|PubMed:21069430,
CC ECO:0000269|PubMed:23510309}.
CC -!- SIMILARITY: Belongs to the AP2/ERF transcription factor family. ERF
CC subfamily. {ECO:0000305}.
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DR EMBL; AC005687; AAC36019.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE31950.1; -; Genomic_DNA.
DR EMBL; AY062847; AAL32925.1; -; mRNA.
DR EMBL; AY114582; AAM47901.1; -; mRNA.
DR EMBL; AF003099; AAC49772.1; -; mRNA.
DR PIR; D96498; D96498.
DR RefSeq; NP_175008.1; NM_103468.4.
DR AlphaFoldDB; Q7G1L2; -.
DR SMR; Q7G1L2; -.
DR BioGRID; 26140; 5.
DR IntAct; Q7G1L2; 5.
DR STRING; 3702.AT1G43160.1; -.
DR PaxDb; Q7G1L2; -.
DR PRIDE; Q7G1L2; -.
DR ProteomicsDB; 236471; -.
DR EnsemblPlants; AT1G43160.1; AT1G43160.1; AT1G43160.
DR GeneID; 840915; -.
DR Gramene; AT1G43160.1; AT1G43160.1; AT1G43160.
DR KEGG; ath:AT1G43160; -.
DR Araport; AT1G43160; -.
DR TAIR; locus:2018635; AT1G43160.
DR eggNOG; ENOG502QV3S; Eukaryota.
DR HOGENOM; CLU_054468_2_0_1; -.
DR InParanoid; Q7G1L2; -.
DR OrthoDB; 1387956at2759; -.
DR PhylomeDB; Q7G1L2; -.
DR PRO; PR:Q7G1L2; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q7G1L2; baseline and differential.
DR Genevisible; Q7G1L2; AT.
DR GO; GO:0005634; C:nucleus; IDA:TAIR.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0034605; P:cellular response to heat; IEP:TAIR.
DR GO; GO:0009658; P:chloroplast organization; IMP:TAIR.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0009873; P:ethylene-activated signaling pathway; IEA:UniProtKB-KW.
DR GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:TAIR.
DR GO; GO:0009737; P:response to abscisic acid; IEP:TAIR.
DR GO; GO:0009409; P:response to cold; IEP:TAIR.
DR GO; GO:0009753; P:response to jasmonic acid; IEP:TAIR.
DR GO; GO:0006970; P:response to osmotic stress; IEP:TAIR.
DR GO; GO:0009751; P:response to salicylic acid; IEP:TAIR.
DR GO; GO:0009651; P:response to salt stress; IMP:TAIR.
DR GO; GO:0009414; P:response to water deprivation; IEP:TAIR.
DR GO; GO:0009611; P:response to wounding; IEP:TAIR.
DR CDD; cd00018; AP2; 1.
DR Gene3D; 3.30.730.10; -; 1.
DR InterPro; IPR001471; AP2/ERF_dom.
DR InterPro; IPR036955; AP2/ERF_dom_sf.
DR InterPro; IPR016177; DNA-bd_dom_sf.
DR InterPro; IPR044808; ERF_plant.
DR PANTHER; PTHR31190; PTHR31190; 1.
DR Pfam; PF00847; AP2; 1.
DR PRINTS; PR00367; ETHRSPELEMNT.
DR SMART; SM00380; AP2; 1.
DR SUPFAM; SSF54171; SSF54171; 1.
DR PROSITE; PS51032; AP2_ERF; 1.
PE 2: Evidence at transcript level;
KW Activator; DNA-binding; Ethylene signaling pathway; Nucleus; Plant defense;
KW Reference proteome; Stress response; Transcription;
KW Transcription regulation.
FT CHAIN 1..192
FT /note="Ethylene-responsive transcription factor RAP2-6"
FT /id="PRO_0000297935"
FT DNA_BIND 60..117
FT /note="AP2/ERF"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00366"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 192 AA; 21963 MW; A7000AE495123B95 CRC64;
MVSMLTNVVS GETEPSASAT WTMGHKRERE EFSLPPQPLI TGSAVTKECE SSMSLERPKK
YRGVRQRPWG KWAAEIRDPH KATRVWLGTF ETAEAAARAY DAAALRFRGS KAKLNFPENV
GTQTIQRNSH FLQNSMQPSL TYIDQCPTLL SYSRCMEQQQ PLVGMLQPTE EENHFFEKPW
TEYDQYNYSS FG
