ID   RAPF_BACSU              Reviewed;         381 AA.
AC   P71002;
DT   16-APR-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1997, sequence version 2.
DT   03-AUG-2022, entry version 132.
DE   RecName: Full=Response regulator aspartate phosphatase F;
DE            EC=3.1.-.-;
GN   Name=rapF; Synonyms=ywhJ; OrderedLocusNames=BSU37460;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9353933; DOI=10.1099/00221287-143-10-3313;
RA   Presecan E., Moszer I., Boursier L., Cruz Ramos H., De La Fuente V.,
RA   Hullo M.-F., Lelong C., Schleich S., Sekowska A., Song B.H., Villani G.,
RA   Kunst F., Danchin A., Glaser P.;
RT   "The Bacillus subtilis genome from gerBC (311 degrees) to licR (334
RT   degrees).";
RL   Microbiology 143:3313-3328(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
CC   -!- INTERACTION:
CC       P71002; P14204: comA; NbExp=5; IntAct=EBI-15961797, EBI-6418022;
CC       P71002; P71001: phrF; NbExp=2; IntAct=EBI-15961797, EBI-15961814;
CC   -!- SIMILARITY: Belongs to the RAP family. {ECO:0000305}.
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DR   EMBL; Z80360; CAB02500.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB15773.1; -; Genomic_DNA.
DR   PIR; A69689; A69689.
DR   RefSeq; NP_391626.1; NC_000964.3.
DR   RefSeq; WP_003227549.1; NZ_JNCM01000034.1.
DR   PDB; 3ULQ; X-ray; 2.30 A; A=2-381.
DR   PDB; 4I9C; X-ray; 3.10 A; A=1-381.
DR   PDB; 4I9E; X-ray; 2.40 A; A/B=1-381.
DR   PDBsum; 3ULQ; -.
DR   PDBsum; 4I9C; -.
DR   PDBsum; 4I9E; -.
DR   AlphaFoldDB; P71002; -.
DR   SMR; P71002; -.
DR   DIP; DIP-59429N; -.
DR   IntAct; P71002; 2.
DR   STRING; 224308.BSU37460; -.
DR   PaxDb; P71002; -.
DR   EnsemblBacteria; CAB15773; CAB15773; BSU_37460.
DR   GeneID; 936725; -.
DR   KEGG; bsu:BSU37460; -.
DR   PATRIC; fig|224308.179.peg.4057; -.
DR   eggNOG; COG0457; Bacteria.
DR   InParanoid; P71002; -.
DR   OMA; GEKINEW; -.
DR   PhylomeDB; P71002; -.
DR   BioCyc; BSUB:BSU37460-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.40.10; -; 1.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   SMART; SM00028; TPR; 4.
DR   SUPFAM; SSF48452; SSF48452; 1.
DR   PROSITE; PS50005; TPR; 4.
DR   PROSITE; PS50293; TPR_REGION; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Hydrolase; Protein phosphatase; Reference proteome; Repeat;
KW   TPR repeat.
FT   CHAIN           1..381
FT                   /note="Response regulator aspartate phosphatase F"
FT                   /id="PRO_0000106440"
FT   REPEAT          101..137
FT                   /note="TPR 1"
FT   REPEAT          148..181
FT                   /note="TPR 2"
FT   REPEAT          182..215
FT                   /note="TPR 3"
FT   REPEAT          222..255
FT                   /note="TPR 4"
FT   REPEAT          262..295
FT                   /note="TPR 5"
FT   REPEAT          337..370
FT                   /note="TPR 6"
FT   HELIX           7..22
FT                   /evidence="ECO:0007829|PDB:3ULQ"
FT   HELIX           26..41
FT                   /evidence="ECO:0007829|PDB:3ULQ"
FT   HELIX           47..67
FT                   /evidence="ECO:0007829|PDB:3ULQ"
FT   HELIX           68..72
FT                   /evidence="ECO:0007829|PDB:3ULQ"
FT   HELIX           75..77
FT                   /evidence="ECO:0007829|PDB:3ULQ"
FT   HELIX           81..91
FT                   /evidence="ECO:0007829|PDB:3ULQ"
FT   HELIX           93..113
FT                   /evidence="ECO:0007829|PDB:3ULQ"
FT   HELIX           117..128
FT                   /evidence="ECO:0007829|PDB:3ULQ"
FT   HELIX           129..133
FT                   /evidence="ECO:0007829|PDB:3ULQ"
FT   HELIX           137..153
FT                   /evidence="ECO:0007829|PDB:3ULQ"
FT   HELIX           157..172
FT                   /evidence="ECO:0007829|PDB:3ULQ"
FT   STRAND          174..176
FT                   /evidence="ECO:0007829|PDB:4I9E"
FT   HELIX           178..194
FT                   /evidence="ECO:0007829|PDB:3ULQ"
FT   HELIX           198..214
FT                   /evidence="ECO:0007829|PDB:3ULQ"
FT   HELIX           218..234
FT                   /evidence="ECO:0007829|PDB:3ULQ"
FT   HELIX           238..254
FT                   /evidence="ECO:0007829|PDB:3ULQ"
FT   HELIX           258..260
FT                   /evidence="ECO:0007829|PDB:3ULQ"
FT   HELIX           261..274
FT                   /evidence="ECO:0007829|PDB:3ULQ"
FT   HELIX           278..295
FT                   /evidence="ECO:0007829|PDB:3ULQ"
FT   HELIX           298..311
FT                   /evidence="ECO:0007829|PDB:3ULQ"
FT   HELIX           317..329
FT                   /evidence="ECO:0007829|PDB:3ULQ"
FT   HELIX           333..349
FT                   /evidence="ECO:0007829|PDB:3ULQ"
FT   HELIX           353..367
FT                   /evidence="ECO:0007829|PDB:3ULQ"
SQ   SEQUENCE   381 AA;  45609 MW;  6F1C0BF6232E739F CRC64;
     MTGVISSSSI GEKINEWYMY IRRFSIPDAE YLRREIKQEL DQMEEDQDLH LYYSLMEFRH
     NLMLEYLEPL EKMRIEEQPR LSDLLLEIDK KQARLTGLLE YYFNFFRGMY ELDQREYLSA
     IKFFKKAESK LIFVKDRIEK AEFFFKMSES YYYMKQTYFS MDYARQAYEI YKEHEAYNIR
     LLQCHSLFAT NFLDLKQYED AISHFQKAYS MAEAEKQPQL MGRTLYNIGL CKNSQSQYED
     AIPYFKRAIA VFEESNILPS LPQAYFLITQ IHYKLGKIDK AHEYHSKGMA YSQKAGDVIY
     LSEFEFLKSL YLSGPDEEAI QGFFDFLESK MLYADLEDFA IDVAKYYHER KNFQKASAYF
     LKVEQVRQLI QGGVSLYEIE V