ID   RARA_COXBU              Reviewed;         440 AA.
AC   P39918;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   09-MAY-2003, sequence version 3.
DT   03-AUG-2022, entry version 118.
DE   RecName: Full=Replication-associated recombination protein A;
GN   Name=rarA; OrderedLocusNames=CBU_1189;
OS   Coxiella burnetii (strain RSA 493 / Nine Mile phase I).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Legionellales; Coxiellaceae;
OC   Coxiella.
OX   NCBI_TaxID=227377;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Oswald W.;
RL   Thesis (1994), Justus Liebig University / Frankfurt, Germany.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RSA 493 / Nine Mile phase I;
RX   PubMed=12704232; DOI=10.1073/pnas.0931379100;
RA   Seshadri R., Paulsen I.T., Eisen J.A., Read T.D., Nelson K.E., Nelson W.C.,
RA   Ward N.L., Tettelin H., Davidsen T.M., Beanan M.J., DeBoy R.T.,
RA   Daugherty S.C., Brinkac L.M., Madupu R., Dodson R.J., Khouri H.M.,
RA   Lee K.H., Carty H.A., Scanlan D., Heinzen R.A., Thompson H.A., Samuel J.E.,
RA   Fraser C.M., Heidelberg J.F.;
RT   "Complete genome sequence of the Q-fever pathogen, Coxiella burnetii.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:5455-5460(2003).
CC   -!- FUNCTION: DNA-dependent ATPase that plays important roles in cellular
CC       responses to stalled DNA replication processes.
CC       {ECO:0000250|UniProtKB:P0AAZ4}.
CC   -!- SIMILARITY: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1
CC       subfamily. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAO90698.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC       Sequence=CAA53291.1; Type=Frameshift; Evidence={ECO:0000305};
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DR   EMBL; X75627; CAA53291.1; ALT_FRAME; Genomic_DNA.
DR   EMBL; AE016828; AAO90698.1; ALT_INIT; Genomic_DNA.
DR   PIR; S43134; S43134.
DR   RefSeq; NP_820184.4; NC_002971.3.
DR   RefSeq; WP_010958061.1; NC_002971.4.
DR   AlphaFoldDB; P39918; -.
DR   SMR; P39918; -.
DR   STRING; 227377.CBU_1189; -.
DR   EnsemblBacteria; AAO90698; AAO90698; CBU_1189.
DR   GeneID; 1209093; -.
DR   KEGG; cbu:CBU_1189; -.
DR   PATRIC; fig|227377.7.peg.1187; -.
DR   eggNOG; COG2256; Bacteria.
DR   HOGENOM; CLU_017985_0_3_6; -.
DR   OMA; RIILSQC; -.
DR   Proteomes; UP000002671; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0008047; F:enzyme activator activity; IBA:GO_Central.
DR   GO; GO:0017116; F:single-stranded DNA helicase activity; IBA:GO_Central.
DR   GO; GO:0006261; P:DNA-templated DNA replication; IBA:GO_Central.
DR   GO; GO:0006282; P:regulation of DNA repair; IBA:GO_Central.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR032423; AAA_assoc_2.
DR   InterPro; IPR003959; ATPase_AAA_core.
DR   InterPro; IPR008921; DNA_pol3_clamp-load_cplx_C.
DR   InterPro; IPR021886; MgsA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00004; AAA; 1.
DR   Pfam; PF16193; AAA_assoc_2; 1.
DR   Pfam; PF12002; MgsA_C; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF48019; SSF48019; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   3: Inferred from homology;
KW   ATP-binding; DNA replication; Nucleotide-binding; Reference proteome.
FT   CHAIN           1..440
FT                   /note="Replication-associated recombination protein A"
FT                   /id="PRO_0000168759"
FT   BINDING         51..58
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000250|UniProtKB:P0AAZ4"
FT   CONFLICT        94
FT                   /note="R -> RVERAER (in Ref. 1)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   440 AA;  49135 MW;  1C2A364169E28DF8 CRC64;
     MLSNNDFIPL ATRMRPGCLE EFVGQSHLLG KDKPLFRAIE KGKLHSMILW GPPGSGKTTL
     AEIIAQKAGA RVESISAVLA GVKDIRDVVE RAERHKGQAT ILFVDEVHGF NKSQQDAFLP
     HVEKGTITLI GATTENPSFQ LNNALLSRTR VYVLKQLTEA DLLSILENAL ANEERGLGKK
     ALEIPEPLRR RIVQFADGDA RQCLNLLEII ADFALEENGR FVVDDGLIDK VLTEGLRRFD
     KRGEAFYDQI SALHKSVRGS DPDASLYWLS RLLDGGCDPF YVARRVVRMA SEDIGNADPR
     ALQLALDAWE TFERLGTPEG ELAIAQAVVY CACAAKSNAV YKAFNAASRE VKSTGSLEVP
     LYLRNAPTRL MKSLDYGKDY RYAHDESDGF AAGVDYLPES LIGRRYYFPI NRGLEIKIKE
     KLEYYRKLNE QHKTTEDSKN