ID   RARA_HAEIN              Reviewed;         446 AA.
AC   P45262;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   03-AUG-2022, entry version 118.
DE   RecName: Full=Replication-associated recombination protein A;
GN   Name=rarA; OrderedLocusNames=HI_1590;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
CC   -!- FUNCTION: DNA-dependent ATPase that plays important roles in cellular
CC       responses to stalled DNA replication processes.
CC       {ECO:0000250|UniProtKB:P0AAZ4}.
CC   -!- SIMILARITY: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1
CC       subfamily. {ECO:0000305}.
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DR   EMBL; L42023; AAC23238.1; -; Genomic_DNA.
DR   PIR; F64172; F64172.
DR   RefSeq; NP_439735.1; NC_000907.1.
DR   RefSeq; WP_010869253.1; NC_000907.1.
DR   AlphaFoldDB; P45262; -.
DR   SMR; P45262; -.
DR   STRING; 71421.HI_1590; -.
DR   DNASU; 950837; -.
DR   EnsemblBacteria; AAC23238; AAC23238; HI_1590.
DR   KEGG; hin:HI_1590; -.
DR   PATRIC; fig|71421.8.peg.1664; -.
DR   eggNOG; COG2256; Bacteria.
DR   HOGENOM; CLU_017985_1_1_6; -.
DR   OMA; RIILSQC; -.
DR   PhylomeDB; P45262; -.
DR   BioCyc; HINF71421:G1GJ1-1606-MON; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0008047; F:enzyme activator activity; IBA:GO_Central.
DR   GO; GO:0017116; F:single-stranded DNA helicase activity; IBA:GO_Central.
DR   GO; GO:0006261; P:DNA-templated DNA replication; IBA:GO_Central.
DR   GO; GO:0006282; P:regulation of DNA repair; IBA:GO_Central.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR032423; AAA_assoc_2.
DR   InterPro; IPR003959; ATPase_AAA_core.
DR   InterPro; IPR008921; DNA_pol3_clamp-load_cplx_C.
DR   InterPro; IPR021886; MgsA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00004; AAA; 1.
DR   Pfam; PF16193; AAA_assoc_2; 1.
DR   Pfam; PF12002; MgsA_C; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF48019; SSF48019; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   3: Inferred from homology;
KW   ATP-binding; DNA replication; Nucleotide-binding; Reference proteome.
FT   CHAIN           1..446
FT                   /note="Replication-associated recombination protein A"
FT                   /id="PRO_0000168758"
FT   BINDING         57..64
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000250|UniProtKB:P0AAZ4"
SQ   SEQUENCE   446 AA;  50217 MW;  0F943B7A3736A4F7 CRC64;
     MSNFNFDFAE NDFGPLAAKM RPTSLEQYFG QSHLIGEGKP LRKAIQAGHI YSMIFWGPPG
     TGKTTLAEII AQRINAEVER ISAVTSGIKE IREAIDRAKQ NRLADRKTIL FVDEVHRFNK
     SQQDAFLPHI EDGTVIFIGA TTENPSFELN NALLSRARVY VLKSLTTAEI EQVLQQAVED
     PKRGLGKERL ILEENLLQVL AEYVNGDARL ALNCLELMVD MADETENGKK IDRTLLKEVL
     GERQARFDKQ GDRFYDLISA LHKSVRGSAP DAALYWYARI LTAGGDPLYV ARRLLAIASE
     DVGNADPRAM QVALAAWDCF SRVGAYEGER AIAQAIIYLS VAPKSNAVYT AFNTAKQQAK
     DLPDYDVPPH LRNAPTNLMK ELGYGTEYRY AHDEPNAYAA GENYFPPELK DTQYYFPTNR
     GMEIQIKEKL ERLREQDKSA VKKRYK